Výsledky vyhledávání

Effect of the menstrual cycle on serum diamine oxidase levels in healthy women

Autor: Yasuhiro Hamada, Makoto Usami, Mari Yamamoto, Akiyo Toda, Misa Yoshio, Yurika Shinohara, Miyuki Yano, Kumiko Satake, Midori Hirai

Publikováno v: Clinical Biochemistry. 46:99-102

Objectives Serum diamine oxidase (DAO) level is employed as a useful marker of intestinal mucosal integrity. As reported previously, the range of serum DAO levels in women is wider than that in men. We hypothesized that the menstrual cycle may affect

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d35b389fa352f55748cf1199bfcd83da
https://doi.org/10.1016/j.clinbiochem.2012.10.013

Zobrazit plný text záznamu

Oxidized Low Density Lipoprotein Activates Peroxisome Proliferator-activated Receptor-α (PPARα) and PPARγ through MAPK-dependent COX-2 Expression in Macrophages

Autor: Norio Ishii, Shokei Kim-Mitsuyama, Kayo Taketa, Hiroyuki Motoshima, Takeshi Nishikawa, Takeshi Matsumura, Motohiro Takeya, Yusuke Murata, Eiichi Araki, Takafumi Senokuchi, Hiroyuki Itabe, Kaku Tsuruzoe, Teruo Kawada, Miyuki Yano

Publikováno v: Journal of Biological Chemistry. 283:9852-9862

It has been reported that oxidized low density lipoprotein (Ox-LDL) can activate both peroxisome proliferator-activated receptor-alpha (PPARalpha) and PPARgamma. However, the detailed mechanisms of Ox-LDL-induced PPARalpha and PPARgamma activation ar

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1206faed8fa12f0f286ccaf5b64d2a66
https://doi.org/10.1074/jbc.m703318200

Zobrazit plný text záznamu

Impact of Mitochondrial Reactive Oxygen Species and Apoptosis Signal–Regulating Kinase 1 on Insulin Signaling

Autor: Eiichi Araki, Koujiro Imoto, Takeshi Nishikawa, Takako Matsuhisa, Hidenori Ichijo, Takeshi Matsumura, Kaku Tsuruzoe, Miyuki Yano, Kazuo Fujisawa, Daisuke Kukidome, Hiroyuki Motoshima, Tetsuya Taguchi, Kazuhiro Sonoda

Publikováno v: Diabetes. 55:1197-1204

Tumor necrosis factor (TNF)-alpha inhibits insulin action; however, the precise mechanisms are unknown. It was reported that TNF-alpha could increase mitochondrial reactive oxygen species (ROS) production, and apoptosis signal-regulating kinase 1 (AS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::449f8a9c821ca51f3554e9d50e834d57
https://doi.org/10.2337/db05-1187

Zobrazit plný text záznamu

Activation of AMP-Activated Protein Kinase Reduces Hyperglycemia-Induced Mitochondrial Reactive Oxygen Species Production and Promotes Mitochondrial Biogenesis in Human Umbilical Vein Endothelial Cells

Autor: Miyuki Yano, Takeshi Nishikawa, Tetsuya Taguchi, Daisuke Kukidome, Eiichi Araki, Koujiro Imoto, Takeshi Matsumura, Kazuhiro Sonoda, Hiroyuki Motoshima, Kazuo Fujisawa

Publikováno v: Diabetes. 55:120-127

We previously proposed that the production of hyperglycemia-induced mitochondrial reactive oxygen species (mtROS) is a key event in the development of diabetes complications. The association between the pathogenesis of diabetes and its complications

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::541c268ca23bc62b7e79abf022fa3347
https://doi.org/10.2337/diabetes.55.01.06.db05-0943

Zobrazit plný text záznamu

Adenosine Monophosphate-Activated Protein Kinase Suppresses Vascular Smooth Muscle Cell Proliferation Through the Inhibition of Cell Cycle Progression

Autor: Eiichi Araki, Motoyuki Igata, Takeshi Nishikawa, Kanou Kojima, Tatsuya Kondo, Takeshi Matsumura, Miyuki Yano, Tetsushi Toyonaga, Kazuhiko Nakamaru, K. Matsumoto, Kaku Tsuruzoe, Tomoichiro Asano, Hiroyuki Motoshima, Daisuke Kukidome, Tetsuya Taguchi

Publikováno v: Circulation Research. 97:837-844

Vascular smooth muscle cell (VSMC) proliferation is a critical event in the development and progression of vascular diseases, including atherosclerosis. We investigated whether the activation of adenosine monophosphate-activated protein kinase (AMPK)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::17bcd840ce61bf98c0d4b0b3597524f2
https://doi.org/10.1161/01.res.0000185823.73556.06

Zobrazit plný text záznamu

Statins Suppress Oxidized Low Density Lipoprotein-induced Macrophage Proliferation by Inactivation of the Small G Protein-p38 MAPK Pathway

Autor: Koujiroh Imoto, Tomoko Matsuo, Eiichi Araki, Masakazu Sakai, Daisuke Kukidome, Miyuki Yano, Tetsuya Taguchi, Takeshi Matsumura, Takeshi Nishikawa, Shokei Kim-Mitsuyama, Kazuhiro Sonoda, Takafumi Senokuchi, Yoh Takuwa

Publikováno v: Journal of Biological Chemistry. 280:6627-6633

Inhibitors of 3-hydroxy-3-methylglutaryl coenzyme A reductase (statins) ameliorate atherosclerotic diseases. Macrophages play an important role in the development and subsequent stability of atherosclerotic plaques. We reported previously that oxidiz

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a650faaf809d0d8ceb40b6a83b610bd
https://doi.org/10.1074/jbc.m412531200

Zobrazit plný text záznamu

15d-PGJ2 inhibits oxidized LDL-induced macrophage proliferation by inhibition of GM-CSF production via inactivation of NF-κB

Autor: Richard G. Pestell, Masakazu Sakai, Takeshi Nishikawa, Shinsuke Kiritoshi, Michael Brownlee, Tomoko Matsuo, Eiichi Araki, Takeshi Matsumura, Kazuhiro Sonoda, Takafumi Senokuchi, Daisuke Kukidome, Miyuki Yano

Publikováno v: Biochemical and Biophysical Research Communications. 314:817-823

Macrophage-derived foam cells play an important role in atherosclerotic lesions. Oxidized low-density lipoprotein (Ox-LDL) induces macrophage proliferation via production of GM-CSF in vitro. This study investigated the effects of 15-deoxy-Delta(12,14

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56b4419b7130b6028d7d405464c0e9ee
https://doi.org/10.1016/j.bbrc.2003.12.161

Zobrazit plný text záznamu

Personal and interactive newscaster agent based on estimation of user's understanding

Autor: Naoto Yoshida, Tomoko Yonezawa, Miyuki Yano

Publikováno v: HAI

In this paper, we propose a virtual agent system that introduces the current news on the Webs depending on the user's reactions to the understanding. We focused on the gesture of the user to estimate the user's state of understanding based on the hea

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e3620e67875012343897cbd8407fb417
https://doi.org/10.1145/2658861.2658877

Zobrazit plný text záznamu

Vyhledávací nástroje:

Upřesnit hledání