Zobrazeno 1 - 10
of 69
pro vyhledávání: '"Miyuki Unekawa"'
Autor:
Tsubasa Takizawa, Keiko Ihara, Miyuki Unekawa, Chisato Iba, Shizuko Kagawa, Narumi Watanabe, Shingo Nakayama, Kaori Sakurai, Naoki Miyazaki, Noriyuki Ishida, Ryo Takemura, Mamoru Shibata, Yoshikane Izawa, Shotaro Chubachi, Koichi Fukunaga, Jin Nakahara
Publikováno v:
The Journal of Headache and Pain, Vol 25, Iss 1, Pp 1-7 (2024)
Abstract Background Patients with migraine are typically advised to avoid passive smoking because it may aggravate headaches and other health conditions. However, there is insufficient high-quality evidence on the association between passive smoking
Externí odkaz:
https://doaj.org/article/95ca109f005b473c8f7c6e45453e7aa2
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 14, p 11578 (2023)
Migraine is a debilitating neurovascular disorder characterized by recurrent headache attacks of moderate to severe intensity. Calcitonin gene-related peptide (GGRP), which is abundantly expressed in trigeminal ganglion (TG) neurons, plays a crucial
Externí odkaz:
https://doaj.org/article/bf6b87931b424249ac649510bd5949e7
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 13803 (2022)
Goreisan, a traditional Japanese Kampo medicine, is often used to treat headaches, including migraines; however, the underlying mechanisms remain unknown. Therefore, we investigated whether chronic treatment with Goreisan affects cortical spreading d
Externí odkaz:
https://doaj.org/article/9d76b17f78354464a4b487b13450ec9d
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 22, p 13807 (2022)
A migraine is clinically characterized by repeated headache attacks that entail considerable disability. Many patients with migraines experience postdrome, the symptoms of which include tiredness and photophobia. Calcitonin gene-related peptide (GGRP
Externí odkaz:
https://doaj.org/article/c44594f9b8234c6eb8459131fff2db79
Autor:
Yoshifumi Abe, Soojin Kwon, Mitsuhiro Oishi, Miyuki Unekawa, Norio Takata, Fumiko Seki, Ryuta Koyama, Manabu Abe, Kenji Sakimura, Kazuto Masamoto, Yutaka Tomita, Hideyuki Okano, Hajime Mushiake, Kenji F. Tanaka
Publikováno v:
Cell Reports, Vol 36, Iss 4, Pp 109427- (2021)
Summary: An artificial tool for manipulating local cerebral blood flow (CBF) is necessary for understanding how CBF controls brain function. Here, we generate vascular optogenetic tools whereby smooth muscle cells and endothelial cells express optica
Externí odkaz:
https://doaj.org/article/530c34d3c03248d6abed02a32d2771c5
Autor:
Miyuki Unekawa, Jin Nakahara, Toshihiko Shimizu, Satoshi Kitagawa, Norihiro Suzuki, Mamoru Shibata, Yohei Kayama, Chunghua Tang
Publikováno v:
Neuroscience Research. 172:80-86
Migraine sufferers often exhibit photophobia and physical hypoactivity in the postdrome and interictal periods, for which no effective therapy currently exists. Cortical spreading depolarization (CSD) is a neural phenomenon underlying migraine aura.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::712d46deffa6af0004e4bfbe8292e5d0
https://doi.org/10.1016/j.neures.2021.03.010
https://doi.org/10.1016/j.neures.2021.03.010
Autor:
Mitsuhiro Oishi, Stefan Passlick, Yoshihiko Yamazaki, Miyuki Unekawa, Ruka Adachi, Mayumi Yamada, Itaru Imayoshi, Yoshifumi Abe, Christian Steinhäuser, Kenji F. Tanaka
Publikováno v:
GliaREFERENCES. 71(2)
Nerve/glial antigen 2 (NG2) is a protein marker of NG2 glia and mural cells, and NG2 promoter activity is utilized to target these cells. However, the NG2 promoter cannot target NG2 glia and mural cells separately. This has been an obstacle for NG2 g
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::965d303f0cc0ceeb63fcbf56c205e721
https://pubmed.ncbi.nlm.nih.gov/36165697
https://pubmed.ncbi.nlm.nih.gov/36165697
Autor:
Hatakeyama, Nao, Miyuki, Unekawa, Juri Murata, Yutaka, Tomita, Norihiro Suzuki, Nakahara, Jin, Hiroyuki, Takuwa, Iwao, Kanno, Matsu, Ko, F Tanaka, Kenji, Kazuto, Masamoto
Publikováno v:
Journal of Cerebral Blood Flow & Metabolism. 41(10):2676-2689
A variety of brain cells participates in neurovascular coupling by transmitting and modulating vasoactive signals. The present study aimed to probe cell type-dependent cerebrovascular (i.e., pial and penetrating arterial) responses with optogenetics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=jairo_______::cad76b902b12682e71afd77292f94d99
https://repo.qst.go.jp/records/84594
https://repo.qst.go.jp/records/84594
Publikováno v:
Brain research. 1792
Clinical and experimental evidence suggests that spreading depolarizations (SD) usually occur in patients with ischemic or hemorrhagic stroke when the gray matter of the brain is affected. In this study, we evaluated spatiotemporal changes of cerebra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e4da5963766ddbd75273a1575a1b9ef4
https://pubmed.ncbi.nlm.nih.gov/35901965
https://pubmed.ncbi.nlm.nih.gov/35901965
Autor:
Yohei Kayama, Satoshi Kitagawa, Mamoru Shibata, Jin Nakahara, Tsubasa Takizawa, Miyuki Unekawa, Chunhua Tang
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-12 (2020)
Scientific Reports
Scientific Reports
Cortical spreading depolarisation (CSD), the neural mechanism underlying migraine aura, may cause headache by sensitising the trigeminal system. Photophobia, the most bothersome accompanying symptom during migraine attacks, is more prevalent in migra
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b911b2dd73706d364ac3d96164caf097
http://link.springer.com/article/10.1038/s41598-020-67948-w
http://link.springer.com/article/10.1038/s41598-020-67948-w