Zobrazeno 1 - 10
of 39
pro vyhledávání: '"Miyuki Shimane"'
Autor:
Miyako Hiramatsu, Kentaro Inamura, Michael H. Jones, Hitoshi Nomura, Hironori Ninomiya, Yuichi Ishikawa, Takeshi Fujiwara, Masaaki Matsuura, Hiroyuki Aburatani, Masaru Ushijima, Takayuki Isagawa, Shumpei Ishikawa, Miyuki Shimane
Publikováno v:
Lung Cancer. 75:119-125
Background Lung adenocarcinoma is heterogeneous regarding histology, etiology and prognosis. Although there have been several attempts to find a subgroup with poor prognosis, it is unclear whether or not adenocarcinoma with neuroendocrine (NE) nature
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b95cc5eea99c78fa7f5eed491bae24f9
https://doi.org/10.1016/j.lungcan.2011.05.028
https://doi.org/10.1016/j.lungcan.2011.05.028
Autor:
Hitoshi Nomura, Keiji Funayama, Miyuki Shimane, Yasuhiro Ebihara, Yumi Saito-Kurimoto, Shigetaka Asano, Koichiro Tsuji
Publikováno v:
Biochemical and Biophysical Research Communications. 396:193-198
The Philadelphia chromosome-positive blastoma, maintained by serial subcutaneous transplantation in nude mice, is a highly proliferating biological mass consisting of homogenous CD34(+)CD38(-) myeloblastoid cells. These cells newly evolved from pluri
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f0b22488255644c91f215fb108d883b
https://doi.org/10.1016/j.bbrc.2010.03.172
https://doi.org/10.1016/j.bbrc.2010.03.172
Autor:
Dieter E. Jenne, Takamitsu Iwata, Nobuo Kamada, Takei Kake, Kiyoshi Habu, Miyuki Shimane, Miho Watanabe, Michiko Kinoshita, Hiroshi Suzuki, Jun-ichi Nezu, Yosuke Kawase, Akio Miyoshi, Otoya Ueda, Kou-ichi Jishage, Asuka Ose
Publikováno v:
Proceedings of the National Academy of Sciences. 99:8903-8908
Peutz–Jeghers syndrome (PJS) is a dominantly inherited human disorder characterized by gastrointestinal hamartomatous polyposis and mucocutaneous melanin pigmentation. LKB1 (STK11) serine/threonine kinase is the product of the causative gene of PJS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9897c4cd9e4a718a4db80de3e095c3a8
https://doi.org/10.1073/pnas.122254599
https://doi.org/10.1073/pnas.122254599
Autor:
Ikumi TAMAI, Yoshimichi SAI, Jun-ichi NEZU, Asuka OKU, Miyuki SHIMANE, Akio KOIZUMI, Akira TSUJI
Publikováno v:
Drug Metabolism and Pharmacokinetics. 16:127-133
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e1d7f0952dd3e167d7ee50028b1d6ce7
https://doi.org/10.2133/dmpk.16.127
https://doi.org/10.2133/dmpk.16.127
Autor:
Daisuke Kobayashi, Jun-ichi Nezu, Asuka Oku, Ikumi Tamai, Miyuki Shimane, Rikiya Ohashi, Akira Tsuji, Yoshimichi Sai
Publikováno v:
Journal of Biological Chemistry. 275:40064-40072
Carnitine is essential for beta-oxidation of fatty acids, and a defect of cell membrane transport of carnitine leads to fatal systemic carnitine deficiency. We have already shown that a defect of the organic cation/carnitine transporter OCTN2 is a pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d5b35901471762825de767a1125dc84e
https://doi.org/10.1074/jbc.m005340200
https://doi.org/10.1074/jbc.m005340200
Autor:
Hiroshi Uchino, Ikumi Tamai, Jun-ichi Nezu, Yoshimichi Sai, Miyuki Shimane, Akira Tsuji, Asuka Oku
Publikováno v:
Biochemical and Biophysical Research Communications. 273:251-260
We identified three novel transporters structurally belonging to the organic anion transporting polypeptide (OATP) family in humans. Since previously known rat oatp1 to 3 do not necessarily correspond to the human OATPs in terms of either tissue dist
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad5f72892900d10ba0de82a25ded140
https://doi.org/10.1006/bbrc.2000.2922
https://doi.org/10.1006/bbrc.2000.2922
Autor:
Asuka Oku, Ikumi Tamai, Akira Tsuji, Miyuki Shimane, Yoshimichi Sai, Rikiya Ohashi, Jun-ichi Nezu
Publikováno v:
Drug Metabolism and Pharmacokinetics. 15:182-188
We identified and characterized novel Na+-dependent carnitine/organic cation transporter family, OCTNs from human and mouse. We isolated two and three members of OCTN family from human and mouse, respectively. OCTNs are present in various tissues, in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0499de6b1e5cd8e2b5eb4d9d7b7c6d97
https://doi.org/10.2133/dmpk.15.182
https://doi.org/10.2133/dmpk.15.182
Autor:
Asuka Oku, Rikiya Ohashi, Hikaru Yabuuchi, Akira Tsuji, Jun-ichi Nezu, Miyuki Shimane, Yoshimichi Sai, Ikumi Tamai
Publikováno v:
Journal of Biological Chemistry. 273:20378-20382
Primary carnitine deficiency, because of a defect of the tissue plasma membrane carnitine transporters, causes critical symptoms. However, the transporter has not been molecularly identified. In this study, we screened a human kidney cDNA library and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70e545bef57962c9ad32c3ae0768cb6a
https://doi.org/10.1074/jbc.273.32.20378
https://doi.org/10.1074/jbc.273.32.20378
Publikováno v:
Experimental Cell Research. 241:36-45
Using the new signal sequence trap (SST) method, we isolated several clones encoding secreted and transmembrane proteins from KUSA cells, a murine osteoblast-like cell line. One isolated novel clone, termed entactin-2, exhibited a high similarity to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::61a2e9c5c314ff98b688bed8ce73ac18
https://doi.org/10.1006/excr.1998.4016
https://doi.org/10.1006/excr.1998.4016
Publikováno v:
Genomics. 45:327-331
A cDNA library enriched for human fetal-specific liver genes was constructed by suppressive subtractive hybridization. EST fls223 generated from this library was found to represent a novel putative serine/threonine (Ser/Thr) kinase. A full-length clo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::09c35fc2b1ffa80cc7ac8c1f9738efe6
https://doi.org/10.1006/geno.1997.4938
https://doi.org/10.1006/geno.1997.4938