Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Miyuki Shiga"'
Publikováno v:
Genes and Environment, Vol 46, Iss 1, Pp 1-7 (2024)
Abstract Background Di(2-ethylhexyl) phthalate (DEHP) is a plasticizer commonly used in a wide variety of products, including medical devices. It is rapidly metabolized in the liver into various metabolites upon absorption through oral ingestion, der
Externí odkaz:
https://doaj.org/article/ab00754d305443eca6bee266ad4bf942
Autor:
Michihiro Igarashi, Shoma Saito, Hikari Ogara, Hiroyuki Nakagawa, Motohiro Nozumi, Ayumu Kuramoto, Susumu Kotani, Kiyotaka Tokuraku, Masahiro Kuragano, Kohei Nishida, Chihiro Doki, Miyuki Shiga
Publikováno v:
Journal of biochemistry. 168(3)
Actin-microtubule crosstalk is implicated in the formation of cellular protrusions, but the mechanism remains unclear. In this study, we examined the regulation of cell protrusion involving a ubiquitously expressed microtubule-associated protein (MAP
Autor:
Katsuyoshi Horibata, Hironao Takasawa, Motoki Hojo, Yuhji Taquahashi, Miyuki Shigano, Satoshi Yokota, Norihiro Kobayashi, Kei-ichi Sugiyama, Masamitsu Honma, Shuichi Hamada
Publikováno v:
Genes and Environment, Vol 44, Iss 1, Pp 1-7 (2022)
Abstract Background Multiwalled carbon nanotubes (MWCNTs) are suspected lung carcinogens because their shape and size are similar to asbestos. Various MWCNT types are manufactured; however, only MWNT-7 is classified into Group 2B by The International
Externí odkaz:
https://doaj.org/article/fc3775cf014146ff9ba06feb5dab0149
Publikováno v:
Journal of applied mechanics. 6:1025-1032
Autor:
Shuichi Hamada, Miyuki Shigano, Yumi Wako, Kazufumi Kawasako, Kensuke Satomoto, Tatsuya Mitsumoto, Takayuki Fukuda, Wakako Ohyama, Takeshi Morita, Makoto Hayashi
Publikováno v:
Genes and Environment, Vol 44, Iss 1, Pp 1-9 (2022)
Abstract Background Currently, revisions to the ICH S1 guidance on rodent carcinogenicity testing are being proposed. Application of this approach would reduce the use of animals in accordance with the 3Rs principles (reduce/refine/replace). The meth
Externí odkaz:
https://doaj.org/article/dcffae53b6f441a4900b515615998fe7
Publikováno v:
Genes and Environment, Vol 43, Iss 1, Pp 1-5 (2021)
Abstract Background The liver micronucleus (MN) assay is an effective and important in vivo test for detecting genotoxic compounds. In particular, the repeated-dose liver MN (RDLMN) assay which greatly facilitates incorporation of the liver MN assay
Externí odkaz:
https://doaj.org/article/2f4c2946c5744a60857ce81186544529
Autor:
Shuichi Hamada, Miyuki Shigano, Satoru Kawakami, Maya Ueda, Hajime Sui, Katsuya Yamada, Soichiro Hagio, Ayaka Momonami, Akihisa Maeda, Yukari Terashima, Wakako Ohyama, Takeshi Morita, Makoto Hayashi
Publikováno v:
Genes and Environment, Vol 41, Iss 1, Pp 1-8 (2019)
Abstract Background The repeated-dose liver micronucleus (RDLMN) assay is an effective and important in vivo test for detecting genotoxic compounds, particularly for those that require metabolic activation to show genotoxicity. In a collaborative stu
Externí odkaz:
https://doaj.org/article/c18356cee9e44b748aa005238a282ea6