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pro vyhledávání: '"Miyuki Ogasa"'
Autor:
Takahiro Yamamoto, Osamu Kishida, Tamana Miyazaki, Miyuki Ogasa, Shusaku Tsutsui, Kenji Watabe, Yoshiji Miyazaki, Yoko Murayama, Tatsuya Kiyohara, Iichiro Shimomura, Yasuhisa Shinomura
Publikováno v:
Cancer Chemotherapy and Pharmacology. 55:393-403
The epidermal growth factor receptor (EGFR) and its ligands are involved in tumor growth, metastasis, angiogenesis, and resistance to chemotherapy. The findings reported here demonstrate that SN38 (the active metabolite of CPT-11) induces the tyrosin