Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Miyuki Murayama"'
Autor:
Ana Beatriz Avelino Barbosa, Beatriz Miyuki Murayama, Ana Clara Ribeiro Romanello, Vagner Basqueroto Martins, Claúdia Cirineo Ferreira Monteiro
Publikováno v:
Projetica, Vol 10, Iss 2, Pp 121-136 (2019)
Social roles are constantly under influence and being altered by external forces. The female gender, for one, is undervalued when it comes to sexual equality, due to the influence of a cultural process. The need for change has made feminism rise in t
Externí odkaz:
https://doaj.org/article/d52dc4ad5fbc4ef3b8fc225eed8627d9
Autor:
Kentaro Tanemura, Takumi Akagi, Miyuki Murayama, Naomi Kikuchi, Ohoshi Murayama, Tsutomu Hashikawa, Yuji Yoshiike, Jung-Mi Park, Keiko Matsuda, Shinobu Nakao, Xiaoyan Sun, Shinji Sato, Haruyasu Yamaguchi, Akihiko Takashima
Publikováno v:
Neurobiology of Disease, Vol 8, Iss 6, Pp 1036-1045 (2001)
Formation of neurofibrillary tangles (NFTs) is the most common feature in several neurodegenerative diseases, including Alzheimer's disease (AD). Here we report the formation of filamentous tau aggregations having a β-sheet structure in transgenic m
Externí odkaz:
https://doaj.org/article/86892c23f7a3455d964bb1eedfb1f77e
Autor:
Naohito Kitamura, Runa Araya, Moeko Kudoh, Haruo Kishida, Tetsuya Kimura, Miyuki Murayama, Akihiko Takashima, Yuriko Sakamaki, Tsutomu Hashikawa, Shingo Ito, Sumio Ohtsuki, Tetsuya Terasaki, Jürgen Wess, Masahisa Yamada
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5159 (2009)
BackgroundThe M(5) muscarinic acetylcholine receptor is known to play a crucial role in mediating acetylcholine dependent dilation of cerebral blood vessels. Previously, we reported that male M(5) muscarinic acetylcholine knockout mice (M5R(-/-) mice
Externí odkaz:
https://doaj.org/article/d9aafa9333594dd5b4e2f06754ac6ec5
Autor:
Tetsuya Kimura, Shunji Yamashita, Shinobu Nakao, Jung-Mi Park, Miyuki Murayama, Tatsuya Mizoroki, Yuji Yoshiike, Naruhiko Sahara, Akihiko Takashima
Publikováno v:
PLoS ONE, Vol 3, Iss 10, p e3540 (2008)
Activation of GSK-3beta is presumed to be involved in various neurodegenerative diseases, including Alzheimer's disease (AD), which is characterized by memory disturbances during early stages of the disease. The normal function of GSK-3beta in adult
Externí odkaz:
https://doaj.org/article/9434b8ac212e4c6abdb5e26a950cdab0
Autor:
Yuji Yoshiike, Tetsuya Kimura, Shunji Yamashita, Hiroyuki Furudate, Tatsuya Mizoroki, Miyuki Murayama, Akihiko Takashima
Publikováno v:
PLoS ONE, Vol 3, Iss 8, p e3029 (2008)
Advanced age and mutations in the genes encoding amyloid precursor protein (APP) and presenilin (PS1) are two serious risk factors for Alzheimer's disease (AD). Finding common pathogenic changes originating from these risks may lead to a new therapeu
Externí odkaz:
https://doaj.org/article/d14f293d5e5642e4a97669ff23a16901
Autor:
Ana Beatriz Avelino Barbosa, Beatriz Miyuki Murayama, Ana Clara Ribeiro Romanello, Vagner Basqueroto Martins, Claúdia Cirineo Ferreira Monteiro
Publikováno v:
Projetica; v. 10, n. 2 (2019); 121-136
Projética Revista Científica de Design
Universidade Estadual de Londrina (UEL)
instacron:UEL
Projetica, Vol 10, Iss 2, Pp 121-136 (2019)
Projética Revista Científica de Design
Universidade Estadual de Londrina (UEL)
instacron:UEL
Projetica, Vol 10, Iss 2, Pp 121-136 (2019)
Social roles are constantly under influence and being altered by external forces. The female gender, for one, is undervalued when it comes to sexual equality, due to the influence of a cultural process. The need for change has made feminism rise in t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=dedup_wf_001::8d6fd19e03e3fdaa6ed7093f928ca1f0
https://www.uel.br/revistas/uel/index.php/projetica/article/view/34758
https://www.uel.br/revistas/uel/index.php/projetica/article/view/34758
Publikováno v:
Journal of Biological Chemistry. 290:29438-29448
Protein interacting with C kinase 1 (PICK1) is a synaptic protein interacting with the AMPA receptor subunits GluA2/3. The interaction between GluA2 and PICK1 is required for the removal of GluA2 from the synaptic plasma membrane during long-term dep
Autor:
Shunji Yamashita, Tatsuya Mizoroki, Miyuki Murayama, Akihiko Takashima, Yoshiyuki Soeda, Tetsuya Kimura, Yuji Yoshiike, Sumihiro Maeda, Naruhiko Sahara
Publikováno v:
Aging Cell. 11:51-62
Oxidative stress is considered to promote aging and age-related disorders such as tauopathy. Although recent reports suggest that oxidative stress under certain conditions possesses anti-aging properties, no such conditions have been reported to amel
Autor:
Sarita Lagalwar, Miyuki Murayama, Boyoung Lee, Naruhiko Sahara, Lester I. Binder, Jung Mi Park, Akihiko Takashima
Publikováno v:
European Journal of Neuroscience. 27:2897-2906
Neurofibrillary tangles (NFTs), comprising human intracellular microtubule-associated protein tau, are one of the hallmarks of tauopathies, including Alzheimer's disease. Recently, a report that caspase-cleaved tau is present in NFTs has led to the h
Autor:
Tetsuya Kimura, Yuji Yoshiike, Akihiko Takashima, Tatsuya Mizoroki, Shunji Yamashita, Miyuki Murayama, Jun-Mi Park, Tetsuya Fukuda, Naruhiko Sahara
Publikováno v:
The EMBO Journal. 26:5143-5152
To investigate how tau affects neuronal function during neurofibrillary tangle (NFT) formation, we examined the behavior, neural activity, and neuropathology of mice expressing wild-type human tau. Here, we demonstrate that aged (>20 months old) mice