Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Miyuki Murata"'
Autor:
Kayo Suzuki, Daiju Iwata, Kenichi Namba, Keitaro Hase, Miki Hiraoka, Miyuki Murata, Nobuyoshi Kitaichi, Richard Foxton, Susumu Ishida
Publikováno v:
PLoS ONE, Vol 18, Iss 11, p e0294745 (2023)
PurposeAngiopoietin (Ang) 2 is released from vascular endothelial cells by the stimulation of vascular endothelial growth factor (VEGF)A. Ang2 increases the expression of leukocyte adhesion molecules on endothelial cells via nuclear factor κB. The a
Externí odkaz:
https://doaj.org/article/ced3bb97ca5043a3bd6674816dd0a266
Publikováno v:
Frontiers in Medicine, Vol 8 (2021)
Objective: Acrolein is a highly reactive aldehyde that covalently binds to cellular macromolecules and subsequently modulates cellular function. Our previous study demonstrated that acrolein induces glial cell migration, a pathological hallmark of di
Externí odkaz:
https://doaj.org/article/4c51029f0ebb4f7ca12a768e2a85e8d2
Autor:
Kanae Fukutsu, MD, Michiyuki Saito, MD, PhD, Kousuke Noda, MD, PhD, Miyuki Murata, PhD, Satoru Kase, MD, PhD, Ryosuke Shiba, Naoki Isogai, Yoshikazu Asano, MD, Nagisa Hanawa, MD, Mitsuru Dohke, MD, Manabu Kase, MD, PhD, Susumu Ishida, MD, PhD
Publikováno v:
Ophthalmology Science, Vol 1, Iss 1, Pp 100004- (2021)
Purpose: To develop a novel evaluation system for retinal vessel alterations caused by hypertension using a deep learning algorithm. Design: Retrospective study. Participants: Fundus photographs (n = 10 571) of health-check participants (n = 5598). M
Externí odkaz:
https://doaj.org/article/67eb3755bc114858b18446f79f53472a
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
With increasing prevalence of diabetes and a progressively aging society, diabetic retinopathy is emerging as one of the global leading causes of blindness. Recent studies have shown that vascular endothelial growth factor (VEGF) plays a central role
Externí odkaz:
https://doaj.org/article/79da432b2f0e466e9ebac3b0f729699e
Autor:
Kasumi Kikuchi, Miyuki Murata, Kousuke Noda, Satoru Kase, Yoshiaki Tagawa, Yasushi Kageyama, Masami Shinohara, Tomohiko Sasase, Susumu Ishida
Publikováno v:
Journal of Diabetes Research, Vol 2020 (2020)
Spontaneously Diabetic Torii (SDT) fatty rat is a novel animal model of type 2 diabetes with obesity. SDT fatty rats develop hyperglycemia, dyslipidemia, and other diabetic complications including ocular disorders; however, diabetic cataract formatio
Externí odkaz:
https://doaj.org/article/ea2169e889494e3e9022f4739742d812
Autor:
Kasumi Kikuchi, Zhenyu Dong, Yasuhiro Shinmei, Miyuki Murata, Atsuhiro Kanda, Kosuke Noda, Takayuki Harada, Susumu Ishida
Publikováno v:
Journal of Ophthalmology, Vol 2020 (2020)
Glaucoma is characterized by axonal degeneration of retinal ganglion cells (RGCs) and apoptotic death of their cell bodies. Lowering intraocular pressure is currently the only way to treat glaucoma, but it is often insufficient to inhibit the progres
Externí odkaz:
https://doaj.org/article/aff539541b9140748e15ac3e4c3512dd
Autor:
Shigetoshi Yokoyama, Yan Cai, Miyuki Murata, Takeshi Tomita, Mitsuhiro Yoneda, Lei Xu, Aprile L Pilon, Raul E Cachau, Shioko Kimura
Publikováno v:
eLife, Vol 7 (2018)
Intracellular lipopolysaccharide (LPS) triggers the non-canonical inflammasome pathway, resulting in pyroptosis of innate immune cells. In addition to its well-known proinflammatory role, LPS can directly cause regression of some tumors, although the
Externí odkaz:
https://doaj.org/article/70789844fe5a470fb8b5e29c4c3f6091
Autor:
Miyuki Murata, Yasutoshi Tsuda, Jun Mohara, Tetsuya Koyano, Toru Takahashi, Toshimasa Uchiyama
Publikováno v:
The Kitakanto Medical Journal. 71:307-310
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4a097267fa2e3832d05aba33fcbca27f
https://doi.org/10.2974/kmj71.307
https://doi.org/10.2974/kmj71.307
Autor:
Kanae Fukutsu, Michiyuki Saito, Kousuke Noda, Miyuki Murata, Satoru Kase, Ryosuke Shiba, Naoki Isogai, Yoshikazu Asano, Nagisa Hanawa, Mitsuru Dohke, Manabu Kase, Susumu Ishida
Publikováno v:
Current eye research. 47(11)
Retinal vessels reflect alterations related to hypertension and arteriosclerosis in the physical status. Previously, we had reported a deep-learning algorithm for automatically detecting retinal vessels and measuring the total retinal vascular area i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8894162702e0775b8fa03f0dc6a74052
https://pubmed.ncbi.nlm.nih.gov/36000916
https://pubmed.ncbi.nlm.nih.gov/36000916
Publikováno v:
Investigative Opthalmology & Visual Science. 64:27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e27ae331e7fe5020f464cf54381ad905
https://doi.org/10.1167/iovs.64.5.27
https://doi.org/10.1167/iovs.64.5.27