Zobrazeno 1 - 10
of 340
pro vyhledávání: '"Miyuki Azuma"'
Autor:
Yuting Yin, Rie Sakakibara, Takayuki Honda, Susumu Kirimura, Pissacha Daroonpan, Masashi Kobayashi, Kohei Ando, Hideki Ujiie, Tatsuya Kato, Kichizo Kaga, Takahiro Mitsumura, Ryoji Nakano, Hiroyuki Sakashita, Shinichi Matsuge, Hironori Ishibashi, Takumi Akashi, Yasuhiro Hida, Takao Morohoshi, Miyuki Azuma, Kenichi Okubo, Yasunari Miyazaki
Publikováno v:
Thoracic Cancer, Vol 14, Iss 20, Pp 1991-2000 (2023)
Abstract Background The efficacy of immune checkpoint inhibitors (ICIs) in pleural mesothelioma has recently been established. The response to ICIs can be predicted by quantitative analysis of cells and their spatial distribution in the tumor microen
Externí odkaz:
https://doaj.org/article/a5f74c16de35468994582ad8a3948c5e
Autor:
Wataru Nishi, Ei Wakamatsu, Hiroaki Machiyama, Ryohei Matsushima, Kensho Saito, Yosuke Yoshida, Tetsushi Nishikawa, Tomohiro Takehara, Hiroko Toyota, Masae Furuhata, Hitoshi Nishijima, Arata Takeuchi, Miyuki Azuma, Makoto Suzuki, Tadashi Yokosuka
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Abstract With recent advances in immune checkpoint inhibitors (ICIs), immunotherapy has become the standard treatment for various malignant tumors. Their indications and dosages have been determined empirically, taking individually conducted clinical
Externí odkaz:
https://doaj.org/article/504d7a530e5c44459a41bf162dcb82a0
Autor:
Hideya Koshino, Mariko Osaka, Tetsuya Shimokawa, Mizuki Kaneda, Seira Taniguchi, Takehiro Minamoto, Ken Yaoi, Miyuki Azuma, Katsuki Higo, Naoyuki Osaka
Publikováno v:
Frontiers in Psychology, Vol 14 (2023)
Recent research has shown that the Default Mode Network (DMN) typically exhibits increased activation during processing of social and personal information but shows deactivation during working memory (WM) tasks. Previously, we reported the Frontal Pa
Externí odkaz:
https://doaj.org/article/027403e5f0fb487cbdc5f3c1127b9953
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Herein, we compared the connectivity of resting-state networks between participants with high and low working memory capacity groups. Brain network connectivity was assessed under both resting and working memory task conditions. Task scans c
Externí odkaz:
https://doaj.org/article/4b741fe37d41484dbafc273a85b6986f
Autor:
Tomohiro Takehara, Ei Wakamatsu, Hiroaki Machiyama, Wataru Nishi, Katsura Emoto, Miyuki Azuma, Kenzo Soejima, Koichi Fukunaga, Tadashi Yokosuka
Publikováno v:
Communications Biology, Vol 4, Iss 1, Pp 1-12 (2021)
Takehara et al performed imaging analysis of microcluster formation between the PD-L1 and PD-L2, which are known to play a role in T cell activation in response to tumour cell signaling. Their analysis showed that the cluster formation inhibited T ce
Externí odkaz:
https://doaj.org/article/f45334598a5740f7ad00ef5926a5af20
Autor:
Kanako Nakayama, Taku Nishijo, Masaaki Miyazawa, Tetsuro Watabe, Miyuki Azuma, Hitoshi Sakaguchi
Publikováno v:
Immunity, Inflammation and Disease, Vol 10, Iss 4, Pp n/a-n/a (2022)
Abstract Introduction Contact hypersensitivity (CHS), a type of delayed‐type hypersensitivity, is induced by hapten exposure to the skin and mucosa. We previously reported that, in a murine model of CHS, the vaginal mucosa (VM) sensitization showed
Externí odkaz:
https://doaj.org/article/c44f130575754963ba8a1e45165eb16b
Publikováno v:
PLoS ONE, Vol 15, Iss 12, p e0243379 (2020)
BackgroundB7-H3 is a member of the B7 family of immune-regulatory ligands and is a costimulatory molecule promoting the T cell response in vitro. We herein investigated the clinical utility of serum soluble B7-H3 (sB7-H3) in patients with non-muscle
Externí odkaz:
https://doaj.org/article/7275fae0e67f4fe29227145a484900af
Publikováno v:
PLoS ONE, Vol 13, Iss 7, p e0199719 (2018)
BACKGROUND:B7-H4 is a member of the B7 family of immune-regulatory ligands and is considered to be a negative regulator of the immune response. We investigated the clinical significance of serum soluble B7-H4 in patients with non-metastatic clear cel
Externí odkaz:
https://doaj.org/article/9454f7b49a594ad29080756d9d1f5154
Autor:
Alessandra De Riva, Maja Wållberg, Francesca Ronchi, Richard Coulson, Andrew Sage, Lucy Thorne, Ian Goodfellow, Kathy D McCoy, Miyuki Azuma, Anne Cooke, Robert Busch
Publikováno v:
PLoS ONE, Vol 12, Iss 8, p e0181964 (2017)
Microbes, including viruses, influence type 1 diabetes (T1D) development, but many such influences remain undefined. Previous work on underlying immune mechanisms has focussed on cytokines and T cells. Here, we compared two nonobese diabetic (NOD) mo
Externí odkaz:
https://doaj.org/article/c98b1959c4fd46a5883ababcc51562fa
Publikováno v:
Journal of Eye Movement Research, Vol 7, Iss 5 (2014)
We investigated the effect of memory load on attentional control using the Reading Span Test (RST), a task that requires working memory capacity. Previous studies have shown that a shortage of working memory resources leads to a deficit of inhibition
Externí odkaz:
https://doaj.org/article/54a308fc57d24cd4a3250903594e5f95