Zobrazeno 1 - 10
of 116
pro vyhledávání: '"Miyuki, Kobara"'
Publikováno v:
Toxicology Reports, Vol 8, Iss , Pp 1087-1097 (2021)
Cardiotoxicity is one of the severe adverse effects of chemotherapeutic agents. Imatinib was previously reported to induce cardiotoxicity. Autophagy is an intracellular bulk protein and organelle degradation process, but its roles in cardiac diseases
Externí odkaz:
https://doaj.org/article/a01a577eb34345d996ad368672d38855
Autor:
Giuseppe Pezzotti, Miyuki Kobara, Tamaki Nakaya, Hayata Imamura, Tenma Asai, Nao Miyamoto, Tetsuya Adachi, Toshiro Yamamoto, Narisato Kanamura, Eriko Ohgitani, Elia Marin, Wenliang Zhu, Ichiro Nishimura, Osam Mazda, Tetsuo Nakata, Koichi Makimura
Publikováno v:
Frontiers in Microbiology, Vol 13 (2022)
The multidrug-resistant Candida auris often defies treatments and presently represents a worldwide public health threat. Currently, the ergosterol-targeting Amphotericin B (AmB) and the DNA/RNA-synthesis inhibitor 5-flucytosine (5-FC) are the two mai
Externí odkaz:
https://doaj.org/article/e09073b8962c42fe96b22c69057da2f2
Autor:
Giuseppe Pezzotti, Miyuki Kobara, Tenma Asai, Tamaki Nakaya, Nao Miyamoto, Tetsuya Adachi, Toshiro Yamamoto, Narisato Kanamura, Eriko Ohgitani, Elia Marin, Wenliang Zhu, Ichiro Nishimura, Osam Mazda, Tetsuo Nakata, Koichi Makimura
Publikováno v:
Frontiers in Microbiology, Vol 12 (2021)
Invasive fungal infections caused by yeasts of the genus Candida carry high morbidity and cause systemic infections with high mortality rate in both immunocompetent and immunosuppressed patients. Resistance rates against antifungal drugs vary among C
Externí odkaz:
https://doaj.org/article/31f168ccdaa0442497712b183394fe63
Publikováno v:
Clinical and Experimental Pharmacology and Physiology. 49:1342-1351
Autophagy is a self-degradation process of cytoplasmic components and occurs in the failing heart. Angiotensin II plays a critical role in the progression of heart failure and induces autophagy. We investigated the mechanism underlying angiotensin II
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff4f2b54c4548baec06949b6336286ed
https://doi.org/10.1111/1440-1681.13719
https://doi.org/10.1111/1440-1681.13719
Publikováno v:
Cardiovascular Drugs and Therapy. 37:53-62
Ventricular arrhythmias (VAs) are a common cause of sudden death in acute myocardial infarction (MI), for which hypertension is a major risk factor. Nicorandil opens ATP-sensitive potassium (KATP) channels, which are expressed by nerve terminals and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d1cb075fa5e954b6fbf5e27877ebc53b
https://doi.org/10.1007/s10557-022-07369-1
https://doi.org/10.1007/s10557-022-07369-1
Publikováno v:
Pharmacology. 107:188-196
Introduction: Angelica acutiloba is one of the crude drugs used in Chinese herbal medicine, and its intake is expected to improve metabolic syndrome-associated disorders. Here, we examined the effects of A. acutiloba extract (AAE) on hypertension and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f42a534837908e813ea291df853142b2
https://doi.org/10.1159/000520982
https://doi.org/10.1159/000520982
Publikováno v:
JAPANESE JOURNAL OF GYNECOLOGIC AND OBSTETRIC ENDOSCOPY. 38:40-43
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::82fe86f13ce501afc3895485d5bae86e
https://doi.org/10.5180/jsgoe.38.1_40
https://doi.org/10.5180/jsgoe.38.1_40
Publikováno v:
Journal of Cardiovascular Translational Research.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::238f6116a9479f311f1db3c063f8ac89
https://doi.org/10.1007/s12265-023-10363-z
https://doi.org/10.1007/s12265-023-10363-z
Publikováno v:
Journal of Hypertension. 41:e175-e176
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f4eb1acbdfe4b00c632ee3f1d6f3ba79
https://doi.org/10.1097/01.hjh.0000914444.01161.44
https://doi.org/10.1097/01.hjh.0000914444.01161.44
Publikováno v:
Toxicology Reports, Vol 8, Iss, Pp 1087-1097 (2021)
Toxicology Reports
Toxicology Reports
Graphical abstract
Highlights • Imatinib increases mitochondrial reactive oxygen species production in cardiomyocytes. • Imatinib induces autophagy as well as apoptosis in cardiomyocytes. • Inhibition of autophagy increases imatinib-induce
Highlights • Imatinib increases mitochondrial reactive oxygen species production in cardiomyocytes. • Imatinib induces autophagy as well as apoptosis in cardiomyocytes. • Inhibition of autophagy increases imatinib-induce
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::328c2717ca66a393b053efa3e6a87c28
http://www.sciencedirect.com/science/article/pii/S2214750021000998
http://www.sciencedirect.com/science/article/pii/S2214750021000998