Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Miyoung Yeom"'
Autor:
Doyoung Kim, Jeongjin Kim, Gyochang Keum, Hak Joong Kim, Rina Kwag, Haeun Lee, Jieon Lee, Yakdol Cho, Byungsun Jeon, Miyoung Yeom, Hyunah Choo, Jiwan Woo
Publikováno v:
Journal of Medicinal Chemistry. 64:13766-13779
5-HT7R belongs to a family of G protein-coupled receptors and is associated with a variety of physiological processes in the central nervous system via the activation of the neurotransmitter serotonin (5-HT). To develop selective and biased 5-HT7R li
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dffb98de43c4b3666d79ad41350537d7
https://doi.org/10.1021/acs.jmedchem.1c01093
https://doi.org/10.1021/acs.jmedchem.1c01093
Autor:
Rina, Kwag, Jieon, Lee, Doyoung, Kim, Haeun, Lee, Miyoung, Yeom, Jiwan, Woo, Yakdol, Cho, Hak Joong, Kim, Jeongjin, Kim, Gyochang, Keum, Byungsun, Jeon, Hyunah, Choo
Publikováno v:
Journal of medicinal chemistry. 64(18)
5-HT
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::1a4a399c1f0f618fe859b3287af66bbe
https://pubmed.ncbi.nlm.nih.gov/34519505
https://pubmed.ncbi.nlm.nih.gov/34519505
Autor:
Soyeon Lee, Kyung Il Choi, Youngjae Kim, Sun-Joon Min, Hak Joong Kim, Miyoung Yeom, Hyewhon Rhim, Hyunah Choo, Jihye Seong, Jinsung Tae
Publikováno v:
Bulletin of the Korean Chemical Society. 39:1083-1089
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1fde55c5f270632d3aeb7eba05b2055b
https://doi.org/10.1002/bkcs.11555
https://doi.org/10.1002/bkcs.11555
Publikováno v:
European Journal of Medicinal Chemistry. 110:302-310
To discover a novel 5-HT7R antagonist for treatment of depression, we designed N-acyl-carbazole derivatives which were synthesized and biologically evaluated against 5-HT7R. Among total 30 compounds synthesized, four compounds 27-30 showed good bindi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e9426a7eaa6923167e0860e0f018144
https://doi.org/10.1016/j.ejmech.2016.01.043
https://doi.org/10.1016/j.ejmech.2016.01.043
Autor:
Hyewhon Rhim, Bongjin Moon, Youhoon Chong, Bryan L. Roth, Jeeyeon Kim, Ghilsoo Nam, Xi Ping Huang, Jinsung Tae, Hyunah Choo, Kang Ho Lee, Il Han Choo, Gyochang Keum, Youngjae Kim, Miyoung Yeom
Publikováno v:
ChemMedChem. 8(11)
The 5-HT7 receptor (5-HT7 R) is a promising therapeutic target for the treatment of depression and neuropathic pain. The 5-HT7 R antagonist SB-269970 exhibited antidepressant-like activity, whereas systemic administration of the 5-HT7 R agonist AS-19
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::37be29fa2aa30765905b566d06925232
https://pubmed.ncbi.nlm.nih.gov/24039134
https://pubmed.ncbi.nlm.nih.gov/24039134
Autor:
Bongjin Moon, Taekeun Kim, Jiyoon Kim, Jaeick Lee, Eun Jeong Lim, Ki Duk Park, Hyunah Choo, Gyochang Keum, Miyoung Yeom, Sun-Joon Min, Seonmi Jo, Il Han Choo, C. Justin Lee, Hyeri Park, Ghilsoo Nam
Publikováno v:
Bioorganicmedicinal chemistry. 21(17)
In Parkinson's disease, the motor impairments are mainly caused by the death of dopaminergic neurons. Among the enzymes which are involved in the biosynthesis and catabolism of dopamine, monoamine oxidase B (MAO-B) has been a therapeutic target of Pa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8bff7e41a130e757a0a61878e55fe0
https://pubmed.ncbi.nlm.nih.gov/23810676
https://pubmed.ncbi.nlm.nih.gov/23810676