Zobrazeno 1 - 10
of 27
pro vyhledávání: '"Miyeko D Mana"'
Autor:
Antje Dittmann, Norman J Kennedy, Nina L Soltero, Nader Morshed, Miyeko D Mana, Ömer H Yilmaz, Roger J Davis, Forest M White
Publikováno v:
Molecular Systems Biology, Vol 15, Iss 8, Pp 1-22 (2019)
Abstract Obesity‐associated type 2 diabetes and accompanying diseases have developed into a leading human health risk across industrialized and developing countries. The complex molecular underpinnings of how lipid overload and lipid metabolites le
Externí odkaz:
https://doaj.org/article/2eb64f4b6f5346b7b141970ec46780b4
Autor:
Ryan P. King, Scott B. Snapper, Jeffrey F. Van Humbeck, Constantine N. Tzouanas, Carly G. K. Ziegler, Vanessa Mitsialis, Tyler Jacks, Benjamin E. Mead, Siyi Huang, Miyeko D. Mana, Alex M. Jaeger, Alex K. Shalek, Andrew W. Navia, Ömer H. Yilmaz, Alex S. Genshaft
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-1 (2021)
Nature Communications
Nature Communications
A cell's phenotype and function are influenced by dynamic interactions with its microenvironment. To examine cellular spatiotemporal activity, we developed SPACECAT-Spatially PhotoActivatable Color Encoded Cell Address Tags-to annotate, track, and is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6b1bca03f80a31f2f64a23de6494ecd4
https://doi.org/10.1038/s41467-021-25672-7
https://doi.org/10.1038/s41467-021-25672-7
Autor:
Constantine N. Tzouanas, Vanessa Mitsialis, Tyler Jacks, Benjamin E. Mead, Scott B. Snapper, Alex M. Jaeger, Jeffrey F. Van Humbeck, Alex S. Genshaft, Siyi Huang, Ömer H. Yilmaz, Ryan P. King, Carly G. K. Ziegler, Alex K. Shalek, Andrew W. Navia, Miyeko D. Mana
Publikováno v:
Nature Communications
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
Nature Communications, Vol 12, Iss 1, Pp 1-15 (2021)
A cell’s phenotype and function are influenced by dynamic interactions with its microenvironment. To examine cellular spatiotemporal activity, we developed SPACECAT—Spatially PhotoActivatable Color Encoded Cell Address Tags—to annotate, track,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02c4e05a82808e895ae9a9f4e9be0064
https://doi.org/10.1038/s41467-021-25279-y
https://doi.org/10.1038/s41467-021-25279-y
Publikováno v:
Am J Physiol Cell Physiol
In vitro, cell cultures are essential tools in the study of intestinal function and disease. For the past few decades, monolayer cellular cultures, such as cancer cell lines or immortalized cell lines, have been widely applied in gastrointestinal res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::166d0e34be89f070d9d4876585853a70
https://doi.org/10.1152/ajpcell.00300.2017
https://doi.org/10.1152/ajpcell.00300.2017
Autor:
Simon Andersson, David M. Sabatini, Tyler Jacks, Eino Markelin, Kirsi H. Pietiläinen, Benjamin F. Cravatt, Kalle Luopajärvi, Olli-Pekka Smolander, Swetha Gopalakrishnan, Ömer H. Yilmaz, Radu M. Suciu, Sharif Iqbal, Petri Auvinen, Ari Ristimäki, Miyeko D. Mana, Nalle Pentinmikko, Tuure Saarinen, Anne Juuti, Jatin Roper, Armand B. Cognetta, Nitin Gupta, Santiago Naranjo, Tuomas Tammela, Pekka Katajisto
Publikováno v:
Nature. 571:398-402
A decline in stem cell function impairs tissue regeneration during ageing, but the role of the stem-cell-supporting niche in ageing is not well understood. The small intestine is maintained by actively cycling intestinal stem cells that are regulated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::de7472c74a8d73b1f6a0d7ec319d6728
https://doi.org/10.1038/s41586-019-1383-0
https://doi.org/10.1038/s41586-019-1383-0
Autor:
Ruslan I. Sadreyev, Chan Young Park, Yijing Zhang, Wang J, Bruun-Rasmussen P, Marianna Halasi, Richard A. Hodin, Priscilla Cheung, Tao Xu, He Wang, Ömer H. Yilmaz, Irit Adini, Shijie He, Nima Saeidi, David T. Breault, Miyeko D. Mana, Wendy Kang, Chetal K, Fernando D. Camargo, Mohad, Ruopeng Wang, Lei P, Stas E, Zhou Z, Shinya Imada, Russell Jo, Jeffrey J. Fredberg
Little is known about how the fibrotic gut stiffening caused by inflammatory bowel diseases (IBD) directs the fate of intestinal stem cells (ISCs). To address this question we first developed a novel long-term culture of quasi-3D gut organoids plated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cb44edac2370fee0d224d282d3f073d8
https://doi.org/10.21203/rs.3.rs-362156/v1
https://doi.org/10.21203/rs.3.rs-362156/v1
Autor:
Ömer H. Yilmaz, Deepa T. Patil, Anthony R. Mattia, Miyeko D. Mana, Lieve G. J. Leijssen, Christina Pfirschke, Gregory Y. Lauwers, Azfar Neyaz, Charlene Condon, Katherine E. Boylan, Richard O. Hynes, Steffen Rickelt, Lawrence R. Zukerberg, Ian Brown, Charles A. Whittaker, Vikram Deshpande, Jatin Roper, Qing Zhao, Runjan Chetty
Publikováno v:
Clin Cancer Res
PMC
PMC
Purpose: Sessile serrated lesions (SSL) are precursors to colon carcinoma, and their distinction from other polyps, in particular hyperplastic polyps (HP), presents significant diagnostic challenges. We evaluated expression patterns in colonic polyps
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::79dc379d84997d0efa2f2e3db2f58922
https://europepmc.org/articles/PMC7073301/
https://europepmc.org/articles/PMC7073301/
Publikováno v:
Cell Stem Cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cf118cd60c242a987e8a32ba22c2215
https://doi.org/10.1016/j.stem.2021.03.001
https://doi.org/10.1016/j.stem.2021.03.001
Autor:
William G. Kaelin, Jennifer Cable, Ralph J. DeBerardinis, Gary J. Patti, Sanika Khare, Marcia C. Haigis, Russell Ericksen, Trudy G. Oliver, Benjamin P. Tu, Lydia W.S. Finley, Santosha Vardhana, Brent R. Stockwell, Aimee L. Edinger, Miyeko D. Mana
Publikováno v:
Ann N Y Acad Sci
Tumor cells have devised unique metabolic strategies to garner enough nutrients to sustain continuous growth and cell division. Oncogenic mutations may alter metabolic pathways to unlock new sources of energy, and cells take the advantage of various
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3596f332f96ce761fcd9519509050c52
https://pubmed.ncbi.nlm.nih.gov/31792987
https://pubmed.ncbi.nlm.nih.gov/31792987
Autor:
Norman J. Kennedy, Miyeko D. Mana, Antje Dittmann, Nina L Soltero, Nader Morshed, Ömer H. Yilmaz, Forest M. White, Roger J. Davis
Publikováno v:
Molecular Systems Biology
Molecular Systems Biology, Vol 15, Iss 8, Pp n/a-n/a (2019)
Molecular Systems Biology, Vol 15, Iss 8, Pp n/a-n/a (2019)
Obesity‐associated type 2 diabetes and accompanying diseases have developed into a leading human health risk across industrialized and developing countries. The complex molecular underpinnings of how lipid overload and lipid metabolites lead to the
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8ed694dadbc4e763a72e22e67eb748e
http://europepmc.org/articles/PMC6674232
http://europepmc.org/articles/PMC6674232