Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Miyazawa, Toshiyuki"'
We propose ratio divergence (RD) learning for discrete energy-based models, a method that utilizes both training data and a tractable target energy function. We apply RD learning to restricted Boltzmann machines (RBMs), which are a minimal model that
Externí odkaz:
http://arxiv.org/abs/2409.07679
Autor:
Aramon, Maliheh, Rosenberg, Gili, Valiante, Elisabetta, Miyazawa, Toshiyuki, Tamura, Hirotaka, Katzgraber, Helmut G.
Publikováno v:
Front. Phys. 7, 48 (2019)
The Fujitsu Digital Annealer (DA) is designed to solve fully connected quadratic unconstrained binary optimization (QUBO) problems. It is implemented on application-specific CMOS hardware and currently solves problems of up to 1024 variables. The DA'
Externí odkaz:
http://arxiv.org/abs/1806.08815
Autor:
Fujieda, Hiroki, Kogami, Masakazu, Sakairi, Masao, Kato, Noriyasu, Makino, Mitsuhiro, Takahashi, Naoki, Miyazawa, Toshiyuki, Harada, Satoko, Yamashita, Tokuyuki
Publikováno v:
In European Journal of Medicinal Chemistry 5 August 2018 156:269-294
Autor:
Takemoto, Kazuya *, Sakuma, Yoshiki, Hirose, Shinichi, Usuki, Tatsuya, Yokoyama, Naoki, Miyazawa, Toshiyuki, Takatsu, Motomu, Arakawa, Yasuhiko
Publikováno v:
In Physica E: Low-dimensional Systems and Nanostructures 2005 26(1):185-189
Autor:
Hiroki Fujieda, Naoki Takahashi, Noriyasu Kato, Satoko Harada, Mitsuhiro Makino, Masao Sakairi, Tokuyuki Yamashita, Masakazu Kogami, Miyazawa Toshiyuki
Publikováno v:
European journal of medicinal chemistry. 156
Glucokinase (GK) is an enzyme that plays an important role as a glucose sensor while maintaining whole body glucose homeostasis. Allosteric activators of GK (GKAs) have the potential to treat type 2 diabetes mellitus. To identify novel GKAs, a series
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a3ed9bfef5d83c27a1761c6ce0b07230
https://pubmed.ncbi.nlm.nih.gov/30006171
https://pubmed.ncbi.nlm.nih.gov/30006171
Akademický článek
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Autor:
Miyazawa, Toshiyuki, Nakaoka, Toshihiro, Usuki, Tatsuya, Tatebayashi, Jun, Arakawa, Yasuhiko, Hirose, Shinichi, Takemoto, Kazuya, Takatsu, Motomu, Yokoyama, Naoki
Publikováno v:
Journal of Applied Physics; Jul2008, Vol. 104 Issue 1, p013504, 8p, 1 Chart, 7 Graphs
Autor:
Takemoto, Kazuya, Takatsu, Motomu, Hirose, Shinichi, Yokoyama, Naoki, Sakuma, Yoshiki, Usuki, Tatsuya, Miyazawa, Toshiyuki, Arakawa, Yasuhiko
Publikováno v:
Journal of Applied Physics; 4/15/2007, Vol. 101 Issue 8, p081720, 5p, 1 Diagram, 4 Graphs
Autor:
Sakairi, Masao, Kogami, Masakazu, Torii, Masafumi, Kataoka, Hiroyo, Fujieda, Hiroki, Makino, Mitsuhiro, Kataoka, Daisuke, Okamoto, Ryuji, Miyazawa, Toshiyuki, Okabe, Morio, Inoue, Megumi, Takahashi, Naoki, Harada, Satoko, Watanabe, Nobuhide
Publikováno v:
In Bioorganic & Medicinal Chemistry Letters 1 August 2012 22(15):5123-5128
Autor:
Hiroki Fujieda, Ryuji Okamoto, Satoko Harada, Mitsuhiro Makino, Naoki Takahashi, Masakazu Kogami, Nobuhide Watanabe, Okabe Morio, Daisuke Kataoka, Hiroyo Kataoka, Masao Sakairi, Megumi Inoue, Masafumi Torii, Miyazawa Toshiyuki
Publikováno v:
Bioorganicmedicinal chemistry letters. 22(15)
We disclosed a novel series of G-protein coupled receptor 119 (GPR119) agonists based on a bicyclic amine scaffold. Through the optimization of hit compound 1, we discovered that the basic nitrogen atom of bicyclic amine played an important role in G
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b8183e217ab79827050042b2e2013464
https://pubmed.ncbi.nlm.nih.gov/22765901
https://pubmed.ncbi.nlm.nih.gov/22765901