Zobrazeno 1 - 10 of 51 pro vyhledávání: '"Miyako Yoshioka"'
1
Akademický článek
Changes in hepato-renal gene expression in microminipigs following a single exposure to a mixture of perfluoroalkyl acids.
Autor: Akiko Sakuma, Haruyo Wasada Ochi, Miyako Yoshioka, Noriko Yamanaka, Mitsutaka Ikezawa, Keerthi S Guruge
Publikováno v: PLoS ONE, Vol 14, Iss 1, p e0210110 (2019)
It is evident that some perfluoroalkyl acids (PFAAs), a group of globally dispersed pollutants, have long biological half-lives in humans and farm animals. However, the effects of PFAAs in domestic animals have not been fully elucidated. The present
Externí odkaz: https://doaj.org/article/e396e5e24df440f6ab5a78e49e9b0e70
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2
Akademický článek
Source-Related Effects of Wastewater on Transcription Factor (AhR, CAR and PXR)-Mediated Induction of Gene Expression in Cultured Rat Hepatocytes and Their Association with the Prevalence of Antimicrobial-Resistant Escherichia coli.
Autor: Keerthi S Guruge, Noriko Yamanaka, Miyuki Sonobe, Wataru Fujizono, Miyako Yoshioka, Masato Akiba, Takehisa Yamamoto, Derrick I Joshua, Keshava Balakrishna, Nobuyoshi Yamashita, Kurunthachalam Kannan, Toshiyuki Tsutsui
Publikováno v: PLoS ONE, Vol 10, Iss 9, p e0138391 (2015)
Extracts of wastewater collected from 4 sewage treatment plants (STPs) receiving effluents from different sources in South India were investigated for their levels of transcription factor-mediated gene induction in primary cultured rat hepatocytes. I
Externí odkaz: https://doaj.org/article/c248c95718c0425f8c370a9b19728b5f
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3
Akademický článek
Subcritical Water Hydrolysis Effectively Reduces the In Vitro Seeding Activity of PrPSc but Fails to Inactivate the Infectivity of Bovine Spongiform Encephalopathy Prions.
Autor: Yuichi Murayama, Miyako Yoshioka, Hiroyuki Okada, Eri Takata, Kentaro Masujin, Yoshifumi Iwamaru, Noriko Shimozaki, Tomoaki Yamamura, Takashi Yokoyama, Shirou Mohri, Yuji Tsutsumi
Publikováno v: PLoS ONE, Vol 10, Iss 12, p e0144761 (2015)
The global outbreak of bovine spongiform encephalopathy (BSE) has been attributed to the recycling of contaminated meat and bone meals (MBMs) as feed supplements. The use of MBMs has been prohibited in many countries; however, the development of a me
Externí odkaz: https://doaj.org/article/f6cd10f90506488fa4aa0fd3fc1836b3
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4
Akademický článek
Insect cell-derived cofactors become fully functional after proteinase K and heat treatment for high-fidelity amplification of glycosylphosphatidylinositol-anchored recombinant scrapie and BSE prion proteins.
Autor: Morikazu Imamura, Nobuko Kato, Hiroyuki Okada, Miyako Yoshioka, Yoshifumi Iwamaru, Yoshihisa Shimizu, Shirou Mohri, Takashi Yokoyama, Yuichi Murayama
Publikováno v: PLoS ONE, Vol 8, Iss 12, p e82538 (2013)
The central event in prion infection is the conformational conversion of host-encoded cellular prion protein (PrP(C)) into the pathogenic isoform (PrP(Sc)). Diverse mammalian species possess the cofactors required for in vitro replication of PrP(Sc)
Externí odkaz: https://doaj.org/article/e2e69a3b82094fc7afdd30e95c0a96b6
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5
Akademický článek
Sulfated dextrans enhance in vitro amplification of bovine spongiform encephalopathy PrP(Sc) and enable ultrasensitive detection of bovine PrP(Sc).
Autor: Yuichi Murayama, Miyako Yoshioka, Kentaro Masujin, Hiroyuki Okada, Yoshifumi Iwamaru, Morikazu Imamura, Yuichi Matsuura, Shigeo Fukuda, Sadao Onoe, Takashi Yokoyama, Shirou Mohri
Publikováno v: PLoS ONE, Vol 5, Iss 10 (2010)
Prions, infectious agents associated with prion diseases such as Creutzfeldt-Jakob disease in humans, bovine spongiform encephalopathy (BSE) in cattle, and scrapie in sheep and goats, are primarily comprised of PrP(Sc), a protease-resistant misfolded
Externí odkaz: https://doaj.org/article/b8a835d01b9341b9bf9d5d227fd7cc18
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9
Synergistic induction of drug-metabolizing enzymes in co-cultures of bovine hepatocytic and sinusoidal cell lines
Autor: Takato Takenouchi, Keerthi S. Guruge, Miyako Yoshioka, Noriko Yamanaka, Hiroshi Kitani
Publikováno v: SC30202005200026
NARO成果DBa
Hepatocyte-derived cell lines provide useful experimental systems for studying liver metabolism. Unlike human and rodents, few hepatocyte-derived cell lines have been generated from cattle. Here, we established two immortalized bovine hepatocyte-deri
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::599ad59a4b611806198337254518ac84
https://pubmed.ncbi.nlm.nih.gov/31722089
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10
Changes in hepato-renal gene expression in microminipigs following a single exposure to a mixture of perfluoroalkyl acids
Autor: Keerthi S. Guruge, Akiko Sakuma, Miyako Yoshioka, Mitsutaka Ikezawa, Haruyo Ochi, Noriko Yamanaka
Publikováno v: PLoS ONE, Vol 14, Iss 1, p e0210110 (2019)
SC30201904180020
NARO成果DBa
OA
CC BY
PLoS ONE
It is evident that some perfluoroalkyl acids (PFAAs), a group of globally dispersed pollutants, have long biological half-lives in humans and farm animals. However, the effects of PFAAs in domestic animals have not been fully elucidated. The present
Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cad7c5196cec09c8a29e6cad977daa9
https://doaj.org/article/e396e5e24df440f6ab5a78e49e9b0e70
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