Výsledky vyhledávání - "Miyako Yoshida"

Akademický článek

Antimicrobial Activity of 2-(Piperazin-1-yl)naphtho[2,3-d]thiazole-4,9-dione against Staphylococcus Strains

Autor: Tamami Haraguchi, Saki Hayashi, Seira Nakasaka, Yoshiro Hatanaka, Toshihiro Nagao, Shigemitsu Tanaka, Miki Yoshii, Fumiko Hara, Masayori Hagimori, Miyako Yoshida

Publikováno v: Molecules, Vol 29, Iss 6, p 1277 (2024)

There is an urgent need to discover and develop novel antibacterial agents. Accordingly, we synthesised 2-(piperazin-1-yl)naphtho[2,3-d]thiazole-4,9-dione (PNT), which exhibits antimicrobial activity. The aim of this study was to characterise PNT as

Externí odkaz: https://doaj.org/article/049d13953c784ddcb5ae8fdbd07c5d19

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Akademický článek

Preparation of siRNA–PLGA/Fabʹ–PLGA mixed micellar system with target cell-specific recognition

Autor: Mai Hazekawa, Takuya Nishinakagawa, Takeshi Mori, Miyako Yoshida, Takahiro Uchida, Daisuke Ishibashi

Publikováno v: Scientific Reports, Vol 11, Iss 1, Pp 1-10 (2021)

Abstract Small interfering RNAs (siRNAs) are susceptible to nucleases and degrade quickly in vivo. Moreover, siRNAs demonstrate poor cellular uptake and cannot cross the cell membrane because of its polyanionic characteristics. To overcome these chal

Externí odkaz: https://doaj.org/article/9b11b42a60154855a4a1652ebfdb9cd5

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Akademický článek

Usefulness and limitations of taste sensors in the evaluation of palatability and taste-masking in oral dosage forms

Autor: Tamami Haraguchi, Miyako Yoshida, Honami Kojima, Takahiro Uchida

Publikováno v: Asian Journal of Pharmaceutical Sciences, Vol 11, Iss 4, Pp 479-485 (2016)

The purpose of this review is to discuss the advantages and limitations of taste sensors in the evaluation of the taste of palatability of different oral dosage forms. First, we consider some ways in which the palatability of various pharmaceutical f

Externí odkaz: https://doaj.org/article/c0a4298b5a994532a65c564dea2b182d

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Akademický článek

Development of Taste Sensor to Detect Non-Charged Bitter Substances

Autor: Jumpei Yoshimatsu, Kiyoshi Toko, Yusuke Tahara, Misaki Ishida, Masaaki Habara, Hidekazu Ikezaki, Honami Kojima, Saeri Ikegami, Miyako Yoshida, Takahiro Uchida

Publikováno v: Sensors, Vol 20, Iss 12, p 3455 (2020)

A taste sensor with lipid/polymer membranes is one of the devices that can evaluate taste objectively. However, the conventional taste sensor cannot measure non-charged bitter substances, such as caffeine contained in coffee, because the taste sensor

Externí odkaz: https://doaj.org/article/fbf134c53e8f45ffbfcc4bfc10b51624

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Akademický článek

A Novel Long-Acting Prostacyclin Agonist (ONO-1301) With an Angiogenic Effect: Promoting Synthesis of Hepatocyte Growth Factor and Increasing Cyclic AMP Concentration via IP-Receptor Signaling

Autor: Takahiro Uchida, Mai Hazekawa, Miyako Yoshida, Kunio Matsumoto, Yoshiki Sakai

Publikováno v: Journal of Pharmacological Sciences, Vol 123, Iss 4, Pp 392-401 (2013)

The purpose of this study was to evaluate the angiogenic potency of ONO-1301, a novel prostacyclin agonist, using a murine sponge model. Solutions of ONO-1301 or hepatocyte growth factor (HGF), as a positive control, were injected into sponges in the

Externí odkaz: https://doaj.org/article/9cd7c84c56c548258e5c67c307272167

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