Zobrazeno 1 - 10
of 35
pro vyhledávání: '"Miyako Udono"'
Autor:
Daiki Kubota, Momoka Sato, Miyako Udono, Akiko Kohara, Masatake Kudoh, Yuichi Ukawa, Kiichiro Teruya, Yoshinori Katakura
Publikováno v:
Nutrients, Vol 16, Iss 19, p 3369 (2024)
Background: Urolithin A (Uro-A), a type of polyphenol derived from pomegranate, is known to improve memory function when ingested, in addition to its direct effect on the skin epidermal cells through the activation of longevity gene SIRT1. However, t
Externí odkaz:
https://doaj.org/article/db7a512b8a3b444f98dd2b935985e8b4
Autor:
Takeshi Goya, Kenichi Horisawa, Miyako Udono, Yasuyuki Ohkawa, Yoshihiro Ogawa, Sayaka Sekiya, Atsushi Suzuki
Publikováno v:
Hepatology Communications, Vol 6, Iss 7, Pp 1725-1740 (2022)
Liver cancer is an aggressive cancer associated with a poor prognosis. Development of therapeutic strategies for liver cancer requires fundamental research using suitable experimental models. Recent progress in direct reprogramming technology has ena
Externí odkaz:
https://doaj.org/article/159d47942270405d87f9b407b8daee68
Publikováno v:
Nutrients, Vol 15, Iss 6, p 1479 (2023)
Carnosine is known to improve brain function. The molecular basis for the carnosine-mediated interaction between intestinal cells and neuronal cells is that carnosine acts on intestinal cells and stimulates exosome secretion, which can induce neurite
Externí odkaz:
https://doaj.org/article/1a23cd5b634147e8a0669c970d99a00c
Autor:
Hiroki Inada, Miyako Udono, Kanae Matsuda-Ito, Kenichi Horisawa, Yasuyuki Ohkawa, Shizuka Miura, Takeshi Goya, Junpei Yamamoto, Masao Nagasaki, Kazuko Ueno, Daisuke Saitou, Mikita Suyama, Yoshihiko Maehara, Wataru Kumamaru, Yoshihiro Ogawa, Sayaka Sekiya, Atsushi Suzuki
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
The conditions to induce human hepatic progenitor cells from other cell types are unclear. Here, the authors reprogram human endothelial cells to hepatic progenitor cells by expressing FOXA3, HNF1A and HNF6, capable of giving rise to hepatocytes and
Externí odkaz:
https://doaj.org/article/3527de58b192426485e6dd796f38531e
Publikováno v:
Nutrients, Vol 14, Iss 14, p 2862 (2022)
Regulatory T cells (Tregs) and CD4+/CD25+ T cells play an important role in the suppression of excessive immune responses, homeostasis of immune function, and oral tolerance. In this study, we screened for food-derived polyphenols that induce Tregs i
Externí odkaz:
https://doaj.org/article/0eb0ebaa4c024585bc5dcd1088834986
Publikováno v:
Cell Reports, Vol 25, Iss 1, Pp 183-198 (2018)
Summary: Recent progress in direct lineage reprogramming has enabled the generation of induced hepatocyte-like (iHep) cells and revealed their potential as an alternative to hepatocytes for medical applications. However, the hepatic functions of iHep
Externí odkaz:
https://doaj.org/article/25bdbeb3aeb84845aea83e26da511e68
Publikováno v:
Nutrients, Vol 13, Iss 8, p 2544 (2021)
γ-Aminobutyric acid (GABA) is a potent bioactive amino acid, and several studies have shown that oral administration of GABA induces relaxation, improves sleep, and reduces psychological stress and fatigue. In a recent study, we reported that exosom
Externí odkaz:
https://doaj.org/article/3bbc96df84364ee8a9da66dbdcad2904
Publikováno v:
Nutrients, Vol 13, Iss 6, p 2087 (2021)
Enhanced telomerase reverse transcriptase (TERT) levels in dermal keratinocytes can serve as a novel target for hair growth promotion. Previously, we identified fisetin using a system for screening food components that can activate the TERT promoter
Externí odkaz:
https://doaj.org/article/2bac127e02f948f0b8d56e1ebbc84fdc
Autor:
Chisato Inoue, Chong Zhao, Yumi Tsuduki, Miyako Udono, Lixiang Wang, Masatoshi Nomura, Yoshinori Katakura
Publikováno v:
npj Aging and Mechanisms of Disease, Vol 3, Iss 1, Pp 1-9 (2017)
Cellular senescence: SMARCD1, a key molecule in lipid accumulation A team led by Yoshinori Katakura at Kyushu University tried to clarify the molecular mechanisms of pathogenesis of fatty liver, focused on SMARCD1, one of the identified senescence-as
Externí odkaz:
https://doaj.org/article/42f29cf05d51441cb928ed551febcc74
Autor:
Kenichi Horisawa, Miyako Udono, Wataru Kumamaru, Yoshihiro Ogawa, Yoshihiko Maehara, Masao Nagasaki, Kazuko Ueno, Junpei Yamamoto, Takeshi Goya, Daisuke Saitou, Kanae Matsuda-Ito, Sayaka Sekiya, Hiroki Inada, Mikita Suyama, Shizuka Miura, Atsushi Suzuki, Yasuyuki Ohkawa
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Nature Communications
Nature Communications
Recent advances have enabled the direct induction of human tissue-specific stem and progenitor cells from differentiated somatic cells. However, it is not known whether human hepatic progenitor cells (hHepPCs) can be generated from other cell types b