Zobrazeno 1 - 10
of 107
pro vyhledávání: '"Miyako Nakano"'
Autor:
Akihiro Harada, Masataka Kunii, Kazuo Kurokawa, Takuya Sumi, Satoshi Kanda, Yu Zhang, Satomi Nadanaka, Koichiro M. Hirosawa, Kazuaki Tokunaga, Takuro Tojima, Manabu Taniguchi, Kenta Moriwaki, Shin-ichiro Yoshimura, Miki Yamamoto-Hino, Satoshi Goto, Toyomasa Katagiri, Satoshi Kume, Mitsuko Hayashi-Nishino, Miyako Nakano, Eiji Miyoshi, Kenichi G. N. Suzuki, Hiroshi Kitagawa, Akihiko Nakano
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-19 (2024)
Abstract Knowledge on the distribution and dynamics of glycosylation enzymes in the Golgi is essential for better understanding this modification. Here, using a combination of CRISPR/Cas9 knockin technology and super-resolution microscopy, we show th
Externí odkaz:
https://doaj.org/article/fd8fce91b1f74602a6b152cacc39ff8a
Publikováno v:
Communications Biology, Vol 5, Iss 1, Pp 1-15 (2022)
Cleavage of the glycan-branching enzyme N-acetylglucosaminyltransferase-V (GnT-V) by signal peptide peptidase-like 3 (SPPL3) protease and extracellular secretion of active glycan GnT-V depend on GnT-V’s own glycosylation state.
Externí odkaz:
https://doaj.org/article/02b58c5f888d4facb73bd2211aa34b20
Autor:
Shojiro Haji, Taiki Ito, Carla Guenther, Miyako Nakano, Takashi Shimizu, Daiki Mori, Yasunori Chiba, Masato Tanaka, Sushil K Mishra, Janet A Willment, Gordon D Brown, Masamichi Nagae, Sho Yamasaki
Publikováno v:
eLife, Vol 11 (2022)
C-type lectin receptors (CLRs) elicit immune responses upon recognition of glycoconjugates present on pathogens and self-components. While Dectin-1 is the best-characterized CLR recognizing β-glucan on pathogens, the endogenous targets of Dectin-1 a
Externí odkaz:
https://doaj.org/article/0bc00d0c503041af8a736de6678a2301
Autor:
Sofia Rodriguez-Gallardo, Susana Sabido-Bozo, Atsuko Ikeda, Misako Araki, Kouta Okazaki, Miyako Nakano, Auxiliadora Aguilera-Romero, Alejandro Cortes-Gomez, Sergio Lopez, Miho Waga, Akihiko Nakano, Kazuo Kurokawa, Manuel Muñiz, Kouichi Funato
Publikováno v:
Cell Reports, Vol 39, Iss 5, Pp 110768- (2022)
Summary: Glycosylphosphatidylinositol-anchored proteins (GPI-APs) exit the endoplasmic reticulum (ER) through a specialized export pathway in the yeast Saccharomyces cerevisiae. We have recently shown that a very-long acyl chain (C26) ceramide presen
Externí odkaz:
https://doaj.org/article/b1e0592b14754e73b6675ad5341e886c
Autor:
Keiko Hanaoka, Shunsuke Takahagi, Kaori Ishii, Miyako Nakano, Yuko Chinuki, Akio Tanaka, Yuhki Yanase, Michihiro Hide
Publikováno v:
Allergology International, Vol 69, Iss 2, Pp 253-260 (2020)
Background: Fish roe allergy is a common health problem in countries where sea food is a major part of the diet, such as Japan. β′-component (β′-c) in fish roe has been identified as a major antigen for patients who show hypersensitivity to var
Externí odkaz:
https://doaj.org/article/c5a8ccf3baf94def9dca03bb14374e04
Autor:
Yuki Ohkawa, Masato Kitano, Kento Maeda, Miyako Nakano, Noriko Kanto, Yasuhiko Kizuka, Masahiro Seike, Arata Azuma, Yoshiki Yamaguchi, Tomomi Ookawara, Eiji Miyoshi, Naoyuki Taniguchi
Publikováno v:
Antioxidants & Redox Signaling. 38:1201-1211
The anticancer function of superoxide dismutases (SODs) is still controversial. Removing superoxide and/or producing oxygen and hydrogen peroxide exhibits both pro- and anti-tumor effects. SOD3 is an extracellular superoxide dismutase and contains a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa554d7852c8f52eb95d48739768dbc2
https://doi.org/10.1089/ars.2022.0010
https://doi.org/10.1089/ars.2022.0010
Autor:
Miyako Nakano, Susana Sabido-Bozo, Kouta Okazaki, Auxiliadora Aguilera-Romero, Sofia Rodriguez-Gallardo, Alejandro Cortes-Gomez, Sergio Lopez, Atsuko Ikeda, Kouichi Funato, Manuel Muñiz
Publikováno v:
PLoS ONE, Vol 16, Iss 9, p e0257435 (2021)
Glycosylphosphatidylinositol (GPI) anchoring of proteins is an essential post-translational modification in all eukaryotes that occurs at the endoplasmic reticulum (ER) and serves to deliver GPI-anchored proteins (GPI-APs) to the cell surface where t
Externí odkaz:
https://doaj.org/article/d314bcf6489d4e8b90bacebc982dad0d
Autor:
Masahiro Okada, Shunsuke Chikuma, Taisuke Kondo, Sana Hibino, Hiroaki Machiyama, Tadashi Yokosuka, Miyako Nakano, Akihiko Yoshimura
Publikováno v:
Cell Reports, Vol 20, Iss 5, Pp 1017-1028 (2017)
Summary: Programmed cell death 1 (PD-1) is highly expressed on exhausted T cells and inhibits T cell activation. Antibodies that block the interaction between PD-1 and its ligand prevent this inhibitory signal and reverse T cell dysfunction, providin
Externí odkaz:
https://doaj.org/article/447b1be0ffb445a390e9d533575a28d9
Autor:
Norihiro Kotani, Tomoyuki Araki, Arisa Miyagawa-Yamaguchi, Tomoko Amimoto, Miyako Nakano, Koichi Honke
Publikováno v:
Integrated Methods in Protein Biochemistry: Part B ISBN: 9780323992640
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8a8ea2c242baa2c66dc571ad367efb4f
https://doi.org/10.1016/bs.mie.2022.07.031
https://doi.org/10.1016/bs.mie.2022.07.031
Autor:
Yasuhiko Kizuka, Shinobu Kitazume, Reiko Fujinawa, Takashi Saito, Nobuhisa Iwata, Takaomi C Saido, Miyako Nakano, Yoshiki Yamaguchi, Yasuhiro Hashimoto, Matthias Staufenbiel, Hiroyuki Hatsuta, Shigeo Murayama, Hiroshi Manya, Tamao Endo, Naoyuki Taniguchi
Publikováno v:
EMBO Molecular Medicine, Vol 7, Iss 2, Pp 175-189 (2015)
Abstract The β‐site amyloid precursor protein cleaving enzyme‐1 (BACE1), an essential protease for the generation of amyloid‐β (Aβ) peptide, is a major drug target for Alzheimer's disease (AD). However, there is a concern that inhibiting BAC
Externí odkaz:
https://doaj.org/article/fb5d8482b98245c9b451c84618505b64