Zobrazeno 1 - 10
of 100
pro vyhledávání: '"Miyako, Tanaka"'
Autor:
Yoshiki Shinoda, Hideki Tatsukawa, Atsushi Yonaga, Ryosuke Wakita, Taishu Takeuchi, Tokuji Tsuji, Miyako Tanaka, Takayoshi Suganami, Kiyotaka Hitomi
Publikováno v:
Cell Death and Disease, Vol 14, Iss 2, Pp 1-14 (2023)
Abstract Macrophages are important components in modulating homeostatic and inflammatory responses and are generally categorized into two broad but distinct subsets: classical activated (M1) and alternatively activated (M2) depending on the microenvi
Externí odkaz:
https://doaj.org/article/60a8363128b6446cb25e9a900b1c1a02
Publikováno v:
Inflammation and Regeneration, Vol 42, Iss 1, Pp 1-8 (2022)
Abstract Chronic inflammation is currently considered as a molecular basis of metabolic syndrome. Particularly, obesity-induced inflammation in adipose tissue is the origin of chronic inflammation of metabolic syndrome. Adipose tissue contains not on
Externí odkaz:
https://doaj.org/article/7afadefcfee94a9992d0a364c3033fc5
Autor:
Ryuji Ohue-Kitano, Hazuki Nonaka, Akari Nishida, Yuki Masujima, Daisuke Takahashi, Takako Ikeda, Akiharu Uwamizu, Miyako Tanaka, Motoyuki Kohjima, Miki Igarashi, Hironori Katoh, Tomohiro Tanaka, Asuka Inoue, Takayoshi Suganami, Koji Hase, Yoshihiro Ogawa, Junken Aoki, Ikuo Kimura
Publikováno v:
JCI Insight, Vol 8, Iss 2 (2023)
Medium-chain triglycerides (MCTs), which consist of medium-chain fatty acids (MCFAs), are unique forms of dietary fat with various health benefits. G protein–coupled 84 (GPR84) acts as a receptor for MCFAs (especially C10:0 and C12:0); however, GPR
Externí odkaz:
https://doaj.org/article/ecafa7ca37954e389e6d0e6f51ad1a89
Autor:
Kento Kurita, Hiroya Ohta, Ibuki Shirakawa, Miyako Tanaka, Yasuyuki Kitaura, Yorihiro Iwasaki, Takashi Matsuzaka, Hitoshi Shimano, Seiichiro Aoe, Hiroshi Arima, Yoshihiro Ogawa, Ayaka Ito, Takayoshi Suganami
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract A growing body of evidence indicates that cellular metabolism is involved in immune cell functions, including cytokine production. Serine is a nutritionally non-essential amino acid that can be generated by de novo synthesis and conversion f
Externí odkaz:
https://doaj.org/article/c78ccae1fd384490939f7565d66e5db1
Autor:
Takayuki Inoue, Bin Fu, Miwako Nishio, Miyako Tanaka, Hisashi Kato, Masashi Tanaka, Michiko Itoh, Hajime Yamakage, Kozue Ochi, Ayaka Ito, Yukihiro Shiraki, Satoshi Saito, Masafumi Ihara, Hideo Nishimura, Atsuhiko Kawamoto, Shian Inoue, Kumiko Saeki, Atsushi Enomoto, Takayoshi Suganami, Noriko Satoh-Asahara
Publikováno v:
Nutrients, Vol 15, Iss 2, p 350 (2023)
The molecular pathogenesis of nonalcoholic steatohepatitis (NASH) includes a complex interaction of metabolic stress and inflammatory stimuli. Considering the therapeutic goals of NASH, it is important to determine whether the treatment can prevent t
Externí odkaz:
https://doaj.org/article/c42618d632764c26aece94b1d0defd87
Autor:
Naoki Yoshioka, Miyako Tanaka, Kozue Ochi, Akiko Watanabe, Kenji Ono, Makoto Sawada, Tomoo Ogi, Michiko Itoh, Ayaka Ito, Yukihiro Shiraki, Atsushi Enomoto, Masatoshi Ishigami, Mitsuhiro Fujishiro, Yoshihiro Ogawa, Takayoshi Suganami
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 140, Iss , Pp 111738- (2021)
Background: Diabetes and obesity contribute to the pathogenesis of nonalcoholic steatohepatitis (NASH) and hepatocellular carcinoma (HCC). However, how diabetes and obesity accelerate liver tumorigenesis remains to be fully understood. Moreover, to v
Externí odkaz:
https://doaj.org/article/02d4b3437efc4482872c321aa51cf391
Autor:
Azusa Kobayashi, Ayaka Ito, Ibuki Shirakawa, Atsushi Tamura, Susumu Tomono, Hideo Shindou, Per Niklas Hedde, Miyako Tanaka, Naotake Tsuboi, Takuji Ishimoto, Sachiko Akashi-Takamura, Shoichi Maruyama, Takayoshi Suganami
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
Accumulating evidence suggests that cholesterol accumulation in leukocytes is causally associated with the development of autoimmune diseases. However, the mechanism by which fatty acid composition influences autoimmune responses remains unclear. To
Externí odkaz:
https://doaj.org/article/15704b94f80744bbb9fe0cc111083c27
Autor:
Yohei Kanamori, Miyako Tanaka, Michiko Itoh, Kozue Ochi, Ayaka Ito, Isao Hidaka, Isao Sakaida, Yoshihiro Ogawa, Takayoshi Suganami
Publikováno v:
iScience, Vol 24, Iss 2, Pp 102032- (2021)
Summary: Although recent evidence suggests the involvement of iron accumulation in the pathogenesis of nonalcoholic steatohepatitis (NASH), the underlying mechanisms remain poorly understood. Previously, we reported a unique histological structure te
Externí odkaz:
https://doaj.org/article/16a03f7777ad4768bb6009dc684fd2ff
Autor:
Siyuan Chen, Takuya Miyazaki, Michiko Itoh, Hiroko Matsumoto, Yuki Moro-oka, Miyako Tanaka, Yuji Miyahara, Takayoshi Suganami, Akira Matsumoto
Publikováno v:
Gels, Vol 8, Iss 2, p 74 (2022)
Recently, phenylboronic acid (PBA) gel containing microneedle (MN) technology with acute and sustained glucose-sensitive functionality has attracted significant research attention. Herein, we report a polyvinyl alcohol(PVA)-coated MNs patch with an i
Externí odkaz:
https://doaj.org/article/ab4389c8296a41d294993d58bce4527a
Autor:
Miyako Tanaka, Takayoshi Suganami
Publikováno v:
Journal of Physical Fitness and Sports Medicine, Vol 6, Iss 4, Pp 227-231 (2017)
Storage of excessive energy as triglycerides is a fundamental function of adipose tissue. Adipose tissue also secrets a number of hormones termed “adipocytokines” or “adipokines” in response to the systemic nutritional status, thereby constit
Externí odkaz:
https://doaj.org/article/23ca467432864ea89baf5e9a0d268807