Tento výsledek nelze pro nepřihlášené uživatele zobrazit.
K zobrazení výsledku je třeba se přihlásit.

Machine learning to estimate the local quality of protein crystal structures.

Autor: Miyaguchi, Ikuko^1,2 (AUTHOR) miyaguchi.ikuko@mv.mt-pharma.co.jp, Sato, Miwa^2,3 (AUTHOR), Kashima, Akiko^1,2 (AUTHOR), Nakagawa, Hiroyuki³ (AUTHOR), Kokabu, Yuichi³ (AUTHOR), Ma, Biao^2,4,5 (AUTHOR), Matsumoto, Shigeyuki² (AUTHOR), Tokuhisa, Atsushi^2,4 (AUTHOR), Ohta, Masateru^2,4 (AUTHOR), Ikeguchi, Mitsunori^2,4,6 (AUTHOR)

Publikováno v: Scientific Reports. 12/8/2021, Vol. 11 Issue 1, p1-13. 13p.

Fused bicyclic heteroarylpiperazine-substituted l-prolylthiazolidines as highly potent DPP-4 inhibitors lacking the electrophilic nitrile group

Autor: Yoshida, Tomohiro, Akahoshi, Fumihiko, Sakashita, Hiroshi, Sonda, Shuji, Takeuchi, Masahiro, Tanaka, Yoshihito, Nabeno, Mika, Kishida, Hiroyuki, Miyaguchi, Ikuko, Hayashi, Yoshiharu

Publikováno v: In Bioorganic & Medicinal Chemistry 15 August 2012 20(16):5033-5041

Transport and inhibition mechanism of the human SGLT2-MAP17 glucose transporter.

Autor: Hiraizumi M; Discovery Technology Laboratories Sohyaku Innovative Research Division, Mitsubishi Tanabe Pharma, Yokohama, Japan. hiraizumi-masahiro4580@g.ecc.u-tokyo.ac.jp.; Department of Chemistry and Biotechnology, Graduate School of Engineering, The University of Tokyo, Tokyo, Japan. hiraizumi-masahiro4580@g.ecc.u-tokyo.ac.jp., Akashi T; DMPK Research Laboratories Sohyaku Innovative Research Division, Mitsubishi Tanabe Pharma, Yokohama, Japan., Murasaki K; Discovery Technology Laboratories Sohyaku Innovative Research Division, Mitsubishi Tanabe Pharma, Yokohama, Japan., Kishida H; Discovery Technology Laboratories Sohyaku Innovative Research Division, Mitsubishi Tanabe Pharma, Yokohama, Japan., Kumanomidou T; Discovery Technology Laboratories Sohyaku Innovative Research Division, Mitsubishi Tanabe Pharma, Yokohama, Japan., Torimoto N; Discovery Technology Laboratories Sohyaku Innovative Research Division, Mitsubishi Tanabe Pharma, Yokohama, Japan., Nureki O; Department of Biological Sciences, Graduate School of Science, The University of Tokyo, Tokyo, Japan. nureki@bs.s.u-tokyo.ac.jp., Miyaguchi I; Discovery Technology Laboratories Sohyaku Innovative Research Division, Mitsubishi Tanabe Pharma, Yokohama, Japan. miyaguchi.ikuko@mv.mt-pharma.co.jp.

Publikováno v: Nature structural & molecular biology [Nat Struct Mol Biol] 2024 Jan; Vol. 31 (1), pp. 159-169. Date of Electronic Publication: 2023 Dec 06.