Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Miya, Haruna"'
Autor:
Miya Haruna, Azumi Ueyama, Yoko Yamamoto, Michinari Hirata, Kumiko Goto, Hiroshi Yoshida, Naoko Higuchi, Tetsuya Yoshida, Yujiro Kidani, Yamami Nakamura, Morio Nagira, Atsunari Kawashima, Kota Iwahori, Yasushi Shintani, Naganari Ohkura, Hisashi Wada
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-12 (2022)
Abstract Regulatory T cells (Tregs) suppress the host immune response and maintain immune homeostasis. Tregs also promote cancer progression and are involved in resistance to immune checkpoint inhibitor treatments. Recent studies identified selective
Externí odkaz:
https://doaj.org/article/51a74d2b5acc4db8a5531e85252d6b2f
Autor:
Yohei Nose, Takuro Saito, Kei Yamamoto, Kotaro Yamashita, Koji Tanaka, Kazuyoshi Yamamoto, Tomoki Makino, Tsuyoshi Takahashi, Atsunari Kawashima, Miya Haruna, Michinari Hirata, Azumi Ueyama, Kota Iwahori, Taroh Satoh, Yukinori Kurokawa, Hidetoshi Eguchi, Yuichiro Doki, Hisashi Wada
Publikováno v:
Cancer Immunology, Immunotherapy. 72:169-181
Immune checkpoint inhibitors (ICIs) have revolutionized cancer treatment. Since clinical benefits are limited to a subset of patients, we aimed to identify peripheral blood biomarkers that predict the efficacy of the anti-programmed cell death protei
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c97c421a3ca70079fa191bb62ecf3693
https://doi.org/10.1007/s00262-022-03240-2
https://doi.org/10.1007/s00262-022-03240-2
Autor:
Miya Haruna, Atsunari Kawashima, Kei Yamamoto, Shinya Urakawa, Tsunekazu Mizushima, Akiko Morimoto-Okazawa, Makoto Yamasaki, Eiichi Sato, Tomoki Makino, Kota Iwahori, Masaki Mori, Yukinori Kurokawa, Yuichiro Doki, Michinari Hirata, Kumiko Goto, Hisashi Wada
Publikováno v:
Cancer Immunology, Immunotherapy. 70:443-452
It remains unclear whether Helicobacter pylori (H. pylori), a major cause of gastric cancer (GC), is involved in other intestinal cancers. In our previous study, ICOS+ Foxp3+ CD4+ T cells (ICOS+ Tregs) in GC tumors were identified as effector Tregs a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9975397fb9ba4c6244713bb57fe4de3a
https://doi.org/10.1007/s00262-020-02696-4
https://doi.org/10.1007/s00262-020-02696-4
Autor:
Hitomi, Kajikawa, Michinari, Hirata, Miya, Haruna, Azumi, Ueyama, Katsutoshi, Hirose, Atsunari, Kawashima, Kota, Iwahori, Kazuhide, Matsunaga, Satoru, Toyosawa, Narikazu, Uzawa, Hisashi, Wada
Publikováno v:
Anticancer research. 42(5)
Tumor immunity in the tumor microenvironment is activated in patients with feasible clinical responses to immune checkpoint inhibitors. The immunological profile of tumor-infiltrating lymphocytes (TILs) obtained from patients with oral squamous cell
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::420bc891c2424eaf52fed571f1c3b825
https://pubmed.ncbi.nlm.nih.gov/35489733
https://pubmed.ncbi.nlm.nih.gov/35489733
Autor:
Yujiro Kidani, Wataru Nogami, Yoshiaki Yasumizu, Atsunari Kawashima, Atsushi Tanaka, Yudai Sonoda, Yumi Tona, Kunitaka Nashiki, Reimi Matsumoto, Masaki Hagiwara, Motonao Osaki, Keiji Dohi, Takayuki Kanazawa, Azumi Ueyama, Mai Yoshikawa, Tetsuya Yoshida, Mitsunobu Matsumoto, Kanji Hojo, Satomi Shinonome, Hiroshi Yoshida, Michinari Hirata, Miya Haruna, Yamami Nakamura, Daisuke Motooka, Daisuke Okuzaki, Yasuko Sugiyama, Makoto Kinoshita, Tatsusada Okuno, Taigo Kato, Koji Hatano, Motohide Uemura, Ryoichi Imamura, Kazunori Yokoi, Atsushi Tanemura, Yasushi Shintani, Tadashi Kimura, Norio Nonomura, Hisashi Wada, Masaki Mori, Yuichiro Doki, Naganari Ohkura, Shimon Sakaguchi
Publikováno v:
Proceedings of the National Academy of Sciences. 119
SignificanceImmunosuppressive Foxp3-expressing regulatory T cells (Tregs) in tumor tissues are assumed to be clonally expanding via recognizing tumor-associated antigens. By single-cell RNA sequencing, we have searched for the molecules that are spec
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d4710bc2308f5adf752d06c10e3ca4b
https://doi.org/10.1073/pnas.2114282119
https://doi.org/10.1073/pnas.2114282119
Autor:
Miya Haruna, Azumi Ueyama, Yoko Yamamoto, Michinari Hirata, Kumiko Goto, Hiroshi Yoshida, Naoko Higuchi, Tetsuya Yoshida, Yujiro Kidani, Yamami Nakamura, Morio Nagira, Atsunari Kawashima, Kota Iwahori, Yasushi Shintani, Naganari Ohkura, Hisashi Wada
Publikováno v:
Scientific reports. 12(1)
Regulatory T cells (Tregs) suppress the host immune response and maintain immune homeostasis. Tregs also promote cancer progression and are involved in resistance to immune checkpoint inhibitor treatments. Recent studies identified selective CCR8 exp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ad897718e284fa4cb0312185d9a6babd
https://pubmed.ncbi.nlm.nih.gov/35354899
https://pubmed.ncbi.nlm.nih.gov/35354899
Autor:
Shinya, Urakawa, Makoto, Yamasaki, Tomoki, Makino, Yukinori, Kurokawa, Kei, Yamamoto, Kumiko, Goto, Miya, Haruna, Michinari, Hirata, Akiko, Morimoto-Okazawa, Atsunari, Kawashima, Kota, Iwahori, Tsunekazu, Mizushima, Eiichi, Sato, Masaki, Mori, Yuichiro, Doki, Hisashi, Wada
Publikováno v:
Cancer immunology, immunotherapy : CII. 70(2)
It remains unclear whether Helicobacter pylori (H. pylori), a major cause of gastric cancer (GC), is involved in other intestinal cancers. In our previous study, ICOS
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::91dad9e08a7605b505907cb10cd892ee
https://pubmed.ncbi.nlm.nih.gov/32803278
https://pubmed.ncbi.nlm.nih.gov/32803278
Autor:
Michinari Hirata, Kota Iwahori, Masaaki Sawada, Kosuke Hiramatsu, Yoko Yamamoto, Satoshi Nakagawa, Shinya Matsuzaki, Miya Haruna, Tadashi Kimura, Kei Yamamoto, Hisashi Wada, Kumiko Goto, Toshihiro Kimura, Akiko Morimoto-Okazawa, Eiji Kobayashi, Atsunari Kawashima, Yutaka Ueda
Publikováno v:
International immunology. 32(6)
Persistent exposure to tumor antigens results in exhausted tumor-infiltrating T cells (TILs) that express the immune checkpoint molecules, PD-1 and Tim3, and lack anti-tumor immunity. To examine the exhausted status of TILs in ovarian cancer, the pot
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ea06d6d8e32564f2bfa372c9766bee5d
https://pubmed.ncbi.nlm.nih.gov/32009163
https://pubmed.ncbi.nlm.nih.gov/32009163