Zobrazeno 1 - 10
of 3 577
pro vyhledávání: '"Mixed lymphocyte reaction"'
Autor:
David A. Horwitz, Ju Hua Wang, Dongin Kim, Chang Kang, Katja Brion, Sean Bickerton, Antonio La Cava
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
We have previously reported that nanoparticles (NPs) loaded with IL-2 and TGF-β and targeted to T cells induced polyclonal T regulatory cells (Tregs) that protected mice from graft-versus-host disease (GvHD). Here, we evaluated whether administratio
Externí odkaz:
https://doaj.org/article/bf7e97bd85f64b0fbcc7aa4e6dd95d31
Autor:
Akiko Hori, Atsuko Takahashi, Yuta Miharu, Satoru Yamaguchi, Masatoshi Sugita, Takeo Mukai, Fumitaka Nagamura, Tokiko Nagamura-Inoue
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 12 (2024)
Introduction: Mesenchymal stromal cells (MSCs) are activated upon inflammation and/or tissue damage and migrate to suppress inflammation and repair tissues. Migration is the first important step for MSCs to become functional; however, the migration p
Externí odkaz:
https://doaj.org/article/103070e48d394e3dad861c0cafa2e5d7
Autor:
Adèle Mangelinck, Agathe Dubuisson, Etienne Becht, Sandra Dromaint-Catesson, Manon Fasquel, Nicolas Provost, Dawid Walas, Hélène Darville, Jean-Pierre Galizzi, Céline Lefebvre, Véronique Blanc, Vincent Lombardi
Publikováno v:
Frontiers in Immunology, Vol 14 (2024)
BackgroundThe Mixed Lymphocyte Reaction (MLR) consists in the allogeneic co-culture of monocytes derived dendritic cells (MoDCs) with T cells from another donor. This in vitro assay is largely used for the assessment of immunotherapy compounds. Never
Externí odkaz:
https://doaj.org/article/8292bbcd2a2a4e09b3a0487e6ee8e6e3
Autor:
Naoya Iwahara, Kiyohiko Hotta, Daiki Iwami, Tatsu Tanabe, Yuka Tanaka, Yoichi M. Ito, Takuya Otsuka, Sachiyo Murai, Yusuke Takada, Haruka Higuchi, Hajime Sasaki, Takayuki Hirose, Hiroshi Harada, Nobuo Shinohara
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Donor-specific antibodies (DSAs) are the main cause of graft loss over time. The direct pathway of alloantigen recognition is important in the pathogenesis of acute rejection. Recent studies have suggested that the direct pathway also contributes to
Externí odkaz:
https://doaj.org/article/a1f384890ea3471c82af9657ddfe3c80
Autor:
Natascha Piede, Melanie Bremm, Anne Farken, Lisa-Marie Pfeffermann, Claudia Cappel, Halvard Bonig, Theres Fingerhut, Laura Puth, Kathrin Vogelsang, Andreas Peinelt, Rolf Marschalek, Matthias Müller, Peter Bader, Zyrafete Kuçi, Selim Kuçi, Sabine Huenecke
Publikováno v:
Cells, Vol 12, Iss 6, p 850 (2023)
Mesenchymal stromal cells (MSCs) have the potential to suppress pathological activation of immune cells and have therefore been considered for the treatment of Graft-versus-Host-Disease. The clinical application of MSCs requires a process validation
Externí odkaz:
https://doaj.org/article/a7c755e7cf274e35b8578d2834c3ce95
Autor:
Yi, Jaeu, Jung, Jisun, Hong, Sung-Wook, Lee, Jun Young, Han, Daehee, Kim, Kwang Soon, Sprent, Jonathan, Surh, Charles D.
Publikováno v:
Proceedings of the National Academy of Sciences of the United States of America, 2019 Jan . 116(3), 1007-1016.
Externí odkaz:
https://www.jstor.org/stable/26574130
Autor:
Tess Nicotra, Aurélie Desnos, Justine Halimi, Hélène Antonot, Loïc Reppel, Thomas Belmas, Alice Freton, Floriane Stranieri, Miryam Mebarki, Jérôme Larghero, Audrey Cras, Lionel Faivre
Publikováno v:
Stem Cell Research & Therapy, Vol 11, Iss 1, Pp 1-10 (2020)
Abstract Background Mesenchymal stem/stromal cells (MSC) have immunomodulatory properties, studied in a wide range of diseases. Validated quality controls must confirm this activity in the context of clinical trials. This study presents a method’s
Externí odkaz:
https://doaj.org/article/a25bc0831754410883a3656fc22dbfe1
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Previous work from our laboratory showed that a CB2 selective agonist, O-1966, blocked the proliferative response of C57BL/6 mouse spleen cells exposed to spleen cells of C3HeB/FeJ mice in vitro in the mixed lymphocyte reaction (MLR). The MLR is wide
Externí odkaz:
https://doaj.org/article/ea44f8c02cfd4d0b9892db7071acca4a
Autor:
Eva Depuydt, Sarah Y. Broeckx, Koen Chiers, Marco Patruno, Laura Da Dalt, Luc Duchateau, Jimmy Saunders, Frederik Pille, Ann Martens, Lore Van Hecke, Jan H. Spaas
Publikováno v:
Frontiers in Veterinary Science, Vol 8 (2022)
The use of mesenchymal stem cells (MSCs) for the treatment of equine tendon disease is widely investigated because of their regenerative and immunomodulatory potential. However, questions have been raised concerning the immunogenic properties of allo
Externí odkaz:
https://doaj.org/article/555b82435a584f77b8d4af7d106fe9bc
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