ZNF521 Enhances MLL-AF9-Dependent Hematopoietic Stem Cell Transformation in Acute Myeloid Leukemias by Altering the Gene Expression Landscape

Autor: Emanuela Chiarella, Annamaria Aloisio, Stefania Scicchitano, Katia Todoerti, Emanuela G. Cosentino, Daniela Lico, Antonino Neri, Nicola Amodio, Heather Mandy Bond, Maria Mesuraca

Publikováno v: International Journal of Molecular Sciences, Vol 22, Iss 19, p 10814 (2021)

Leukemias derived from the MLL-AF9 rearrangement rely on dysfunctional transcriptional networks. ZNF521, a transcription co-factor implicated in the control of hematopoiesis, has been proposed to sustain leukemic transformation in collaboration with

Externí odkaz: https://doaj.org/article/7e10324a1a9741248b4885873df710b7

ZNF521 Enhances MLL-AF9-Dependent Hematopoietic Stem Cell Transformation in Acute Myeloid Leukemias by Altering the Gene Expression Landscape

Autor: Daniela Lico, Annamaria Aloisio, Heather M. Bond, Emanuela Chiarella, Stefania Scicchitano, Emanuela G Cosentino, Maria Mesuraca, Antonino Neri, Katia Todoerti, Nicola Amodio

Publikováno v: International Journal of Molecular Sciences
Volume 22
Issue 19
International Journal of Molecular Sciences, Vol 22, Iss 10814, p 10814 (2021)
International Journal of Molecular Sciences, 22(19):10814. MDPI AG

Leukemias derived from the MLL-AF9 rearrangement rely on dysfunctional transcriptional networks. ZNF521, a transcription co-factor implicated in the control of hematopoiesis, has been proposed to sustain leukemic transformation in collaboration with

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1430fc909f53f428530f54bfaf711db8
https://research.rug.nl/en/publications/3ca7e707-4a48-4cbe-b532-2bb2c3c47ad9

Constitutive activation of nuclear factor kappa B-inducing kinase counteracts apoptosis in cells with rearranged mixed lineage leukemia gene

Autor: Maja Studencka-Turski, Michael Naumann, Michael Hartmut Feige, Gunter Maubach

Publikováno v: Leukemia. 32:2498-2501

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3039a6ac68849ee1290ac94184dbae4
https://doi.org/10.1038/s41375-018-0128-7

Amplification of mixed lineage leukemia gene perturbs hematopoiesis and cooperates with partial tandem duplication to induce acute myeloid leukemia

Autor: Jayant K. Rane, Winston Vetharoy, Chiou Tsun Tsai, Eduardo Anguita, Shuo Dong, Chi Wai Eric So, Michael A. Caligiuri, Bon Ham Yip

Publikováno v: Yip, B H, Tsai, C T, Rane, J K, Vetharoy, W, Anguita, E, Dong, S, Caligiuri, M A & So, E 2017, ' Amplification of mixed lineage leukemia gene perturbs hematopoiesis and cooperates with partial tandem duplication to induce acute myeloid leukemia ', Haematologica, vol. 102, no. 8, pp. e300-e304 . https://doi.org/10.3324/haematol.2016.161406

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b4babebbf47e9504ba8267f6f541b389
https://pubmed.ncbi.nlm.nih.gov/28522575

Spontaneous Splenic Rupture in Acute Myeloid Leukemia with Mixed-Lineage Leukemia Gene Rearrangement

Autor: Bao L, Gardner Ja, Ornstein Dl

Publikováno v: Medical Reports & Case Studies.

Spontaneous splenic rupture is a rare and potentially devastating entity associated with a wide variety of causes including, but not limited to, infections, inflammation, and neoplastic and iatrogenic causes. The clinical presentation of spontaneous

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::475153ed9a1cc3659f43f85eb1dcd642
https://doi.org/10.4172/2572-5130.1000119