Zobrazeno 1 - 10
of 32
pro vyhledávání: '"Miwako Ozaki"'
Autor:
Taisuke Kato, Atsushi Kasai, Makoto Mizuno, Liang Fengyi, Norihito Shintani, Sadaaki Maeda, Minesuke Yokoyama, Miwako Ozaki, Hiroyuki Nawa
Publikováno v:
PLoS ONE, Vol 5, Iss 12, p e14185 (2010)
BACKGROUND: Neuregulin-1 (NRG1) is one of the susceptibility genes for schizophrenia and implicated in the neurotrophic regulation of GABAergic and dopaminergic neurons, myelination, and NMDA receptor function. Postmortem studies often indicate a pat
Externí odkaz:
https://doaj.org/article/d318c901c4624841863f0a521b29b8b5
Autor:
Yixin Lu, Xiaoyu Wu, Miwako Ozaki, Satoshi Arai, Shinji Takeoka, Masao Takabayashi, Su In Yoon, Atsushi Murata
Publikováno v:
Biochemical and Biophysical Research Communications. 404:211-216
A specific protein fluorescent labeling method has been used as a tool for bio-imaging in living cells. We developed a novel system of switching "fluorescent turn on" by the recognition of a fluorescent probe to a hexahistidine-tagged (His-tag) prote
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 20:6905-6908
Hexahistidine ((His)(6)) tags are used to purify genetically engineered proteins. Herein, we describe the construction of a 'turn-on' fluorescent probe system that consists of the fluorescence quencher, Dabcyl, conjugated to (His)(6), and fluorescent
Autor:
Taisuke Kato, Akiyoshi Kakita, Yuichi Abe, Sachiko Hirokawa, Hidekazu Sotoyama, Miwako Ozaki, R Kominami, Hitoshi Takahashi, Hiroyuki Nawa
Publikováno v:
Molecular Psychiatry. 16:307-320
Neuregulin-1 (NRG1) is implicated in the etiology or pathology of schizophrenia, although its biological roles in this illness are not fully understood. Human midbrain dopaminergic neurons highly express NRG1 receptors (ErbB4). To test its neuropatho
Publikováno v:
Neurosignals. 16:260-277
One of the major challenges in brain research is to unravel a network of molecules, neurons, circuits and systems that are responsible for dynamic and hierarchical brain functions. To understand molecular events that occur in synapses could be an imp
Autor:
Keiko Tadokoro, Kazuaki Nagao, Miwako Ozaki, Mina Fujishiro, Masao Yamada, Maki Tachibana, Mayu Yamazaki-Inoue, Masashi Toyoda, Masami Ono, Nobuhiro Miki, Toshiyuki Miyashita
Publikováno v:
Journal of Human Genetics. 50:382-394
Protein isoforms with or without a single amino acid residue make a subtle difference. It has been documented on a few genes that alternative splicing generated such isoforms; however, the fact has attracted little attention. We became aware of a sub
Autor:
Yoshihiro Ishihara, Toshiro Kumanishi, Yukie Miyakawa, Ryoji Yano, Kazutaka Ikeda, Tomio Ichikawa, Tsutomu Hashikawa, Miwako Ozaki
Publikováno v:
European Journal of Neuroscience. 16:565-574
In weaver mutant mice, substitution of an amino acid residue in the pore region of GIRK2, a subtype of the G-protein-coupled inwardly rectifying K+ channel, changes the properties of the homomeric channel to produce a lethal depolarized state in cere
Publikováno v:
Neuroscience Research. 30:351-354
We have examined the expression of ErbB2, ErbB3 and ErbB4 in developing mouse cerebellum. ErbB2, ErbB3 and ErbB4 were all expressed in granule cells during cerebellar development. However, the expression pattern for each ErbB receptor changed with th
Publikováno v:
Nature. 390:691-694
Neuregulins (also known as ARIA, NDF, heregulin, GGF) are a family of widely expressed growth and differentiation factors. Neuregulins secreted from motor neurons accumulate at maturing neuromuscular junctions, where they stimulate transcription of g
Publikováno v:
Journal of Neurobiology. 33:735-748
Cell adhesion molecule (CAM) expression is highly regulated during nervous system development to control cell migration, neurite outgrowth, fasciculation, and synaptogenesis. Using electrical stimulation of mouse dorsal root ganglion (DRG) neurons in