Zobrazeno 1 - 3
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pro vyhledávání: '"Miwa Ide"'
Publikováno v:
International Congress Series. 1258:239-243
Mutation of the p53 gene is the most common genetic alteration observed in human cancers. It has been widely reported that cells with mutant p53 change radiation sensitivity. The specific mutations were not discussed in these reports. Radiation sensi
Autor:
Kumio, Okaichi, Miwa, Ide-Kanematsu, Nanaka, Izumi, Naoko, Morita, Yutaka, Okumura, Makoto, Ihara
Publikováno v:
Anticancer research. 28(5A)
Mutation of p53 is the most common genetic alteration observed in human tumours and is reported to lead to variations in cell radiosensitivity. However, the relationship between the mutation point and the degree of radiosensitivity is unclear. Saos-2
Publikováno v:
Journal of radiation research. 45(3)
We investigated the p53 signaling pathway induced by hypergravity in the human glioblastoma cell line A 172. Hypergravity (20×g) induced the accumulation of p53 and the phosphorylation of p53 at Ser-15. The phosphorylation of p53 with hypergravity w