Zobrazeno 1 - 10
of 78
pro vyhledávání: '"Mivazerol"'
Publikováno v:
Acta Anaesthesiologica Scandinavica. 52:997-1002
BACKGROUND: We have previously reported that mivazerol, a alpha(2)-agonist, possibly provides neuroprotection against transient forebrain ischemia in rats. This study was designed to investigate the ability of mivazerol to attenuate ischemia-induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8091f3e3372328708d2a9e095ac44b82
https://doi.org/10.1111/j.1399-6576.2008.01683.x
https://doi.org/10.1111/j.1399-6576.2008.01683.x
Publikováno v:
Acta Anaesthesiologica Scandinavica. 49:1117-1123
Background: We examined whether mivazerol, an α2-agonist, had neuroprotective effects after transient forebrain ischemia in rats. Methods: Male Sprague-Dawley rats, anesthetized with halothane, were assigned to one of four groups (n = 10 each): cont
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::27ca7f3987138d46494c711412faebec
https://doi.org/10.1111/j.1399-6576.2005.00794.x
https://doi.org/10.1111/j.1399-6576.2005.00794.x
Publikováno v:
Journal of Neurochemistry. 67:636-644
In this study, we have investigated the effect of mivazerol, [3-(1H-imidazol-4-yl)methyl-1]-2-hydroxy-benzamide hydrochloride, a new alpha2-agonist lacking hypotensive properties and a potential anti-ischemic drug, on the evoked release of norepineph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6ebbe8634ecb0e881c34bcd3445bacc3
https://doi.org/10.1046/j.1471-4159.1996.67020636.x
https://doi.org/10.1046/j.1471-4159.1996.67020636.x
Publikováno v:
ains · Anästhesiologie · Intensivmedizin · Notfallmedizin · Schmerztherapie. 35:515-522
OBJECTIVE During and after surgical procedures a strong activation of the sympatho-adrenergic system is common with correlation to adverse cardiac outcome. Several drugs (alpha 2-adrenoceptor-agonists, beta blockers) are discussed to prevent this rea
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c7dbf21ffd9b3c6a193bde39dc4d82bd
https://doi.org/10.1055/s-2000-7082
https://doi.org/10.1055/s-2000-7082
Autor:
Johann Motsch
Publikováno v:
Best Practice & Research Clinical Anaesthesiology. 14:369-380
Surgery-induced hyperdynamic cardiac responses compromise the myocardial oxygen supply ratio. Patients with coronary artery disease are therefore at risk of peri-operative myocardial ischaemia, which may result in an adverse cardiac outcome. A predom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d389d6fe83b3daed8a3bcc822f5ce1a7
https://doi.org/10.1053/bean.2000.0089
https://doi.org/10.1053/bean.2000.0089
Publikováno v:
Best Practice & Research Clinical Anaesthesiology. 14:449-458
In December 1999, the United States Food and Drug Administration approved dexmedetomidine, the active isomer of medetomidine, a veterinary anaesthetic, for use in the ICU. Dexmedetomidine is far more potent and selective as an α 2 -agonist than clon
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::30e25ecb677f782821adebd016d5c3c7
https://doi.org/10.1053/bean.2000.0096
https://doi.org/10.1053/bean.2000.0096
Publikováno v:
Fundamental & Clinical Pharmacology. 13:455-460
The aim of this study was to evaluate the ability of H3-histaminergic prejunctional receptors to modulate the noradrenaline release induced by myocardial ischaemia in the rat, and the effects of an eventual modulation on haemodynamic, biochemical and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::290bc867f27bd5acf1684c889f5a16ea
https://doi.org/10.1111/j.1472-8206.1999.tb00003.x
https://doi.org/10.1111/j.1472-8206.1999.tb00003.x
Publikováno v:
Anaesthesia. 54:146-165
Clonidine has proved to be a clinically useful adjunct in clinical anaesthetic practice as well as in chronic pain therapy because it has both anaesthetic and analgesic-sparing activity. The more selective alpha-2 adrenoceptor agonists, dexmedetomidi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::955003ef29305849c611dd63e3efc413
https://doi.org/10.1046/j.1365-2044.1999.00659.x
https://doi.org/10.1046/j.1365-2044.1999.00659.x
Publikováno v:
British Journal of Pharmacology. 125:441-446
1. In order to resolve the extent to which presynaptic noradrenergic mechanisms contribute to the anaesthetic-sparing effects of alpha2-adrenoceptor agonists in vivo microdialysis was used to investigate the combined effects of sodium pentobarbitone
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::eb310eda736946bb2d014dfd3c9a816b
https://doi.org/10.1038/sj.bjp.0702091
https://doi.org/10.1038/sj.bjp.0702091
Publikováno v:
Acta Anaesthesiologica Scandinavica. 42:1004-1009
BACKGROUND Mivazerol is a new and selective alpha 2-adrenergic receptor agonist devoid of hypotensive effects (1, 2). Previous studies have demonstrated that mivazerol prevents hemodynamic instability during emergence from halothane anesthesia in rat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c3fe2318a0f08729718a87dd237720ae
https://doi.org/10.1111/j.1399-6576.1998.tb05362.x
https://doi.org/10.1111/j.1399-6576.1998.tb05362.x