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Publikováno v:
東北薬科大学研究誌. 51:23-29
Aromatase is a cytochrome P-450 enzyme responsible for the conversion of androgens to estrogens. 2,2-Dimethylandrostenedione (5) is one of the powerful inhibitors of the enzyme. To explore a metabolic switching in the aromatase-catalyzed biotransform