Zobrazeno 1 - 10
of 236
pro vyhledávání: '"Mitsuyoshi, Nakao"'
Autor:
Mitsuyoshi Nakao, Kenichi Nagase
Publikováno v:
Regenerative Therapy, Vol 26, Iss , Pp 80-88 (2024)
Introduction: Human umbilical cord-derived mesenchymal stem cells (UC-MSCs) are promising candidates for stem cell therapy. Various methods such as enzymatic treatment, cell scraping, and temperature reduction using temperature-responsive cell cultur
Externí odkaz:
https://doaj.org/article/8531308ddf9444b880604549fb94c114
Autor:
Mitsuyoshi Nakao, Makoto Matsui, Kyungsook Kim, Nobuhiro Nishiyama, David W. Grainger, Teruo Okano, Hideko Kanazawa, Kenichi Nagase
Publikováno v:
Stem Cell Research & Therapy, Vol 14, Iss 1, Pp 1-13 (2023)
Abstract Background Human umbilical cord-derived mesenchymal stem cell (hUC-MSC) sheets have recently attracted attention as an alternative approach to injected cell suspensions for stem cell therapy. However, cell engraftment and cytokine expression
Externí odkaz:
https://doaj.org/article/28612099fab3433ba9b9fe1f95d5d0db
Autor:
Naohiro Kuwayama, Tomoya Kujirai, Yusuke Kishi, Rina Hirano, Kenta Echigoya, Lingyan Fang, Sugiko Watanabe, Mitsuyoshi Nakao, Yutaka Suzuki, Kei-ichiro Ishiguro, Hitoshi Kurumizaka, Yukiko Gotoh
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-18 (2023)
Abstract Identification of factors that regulate chromatin condensation is important for understanding of gene regulation. High-mobility group AT-hook (HMGA) proteins 1 and 2 are abundant nonhistone chromatin proteins that play a role in many biologi
Externí odkaz:
https://doaj.org/article/7f8d3463872a484badc42ef07230b985
Autor:
Yoshiki Hayashi, Soshiro Kashio, Kazutoshi Murotomi, Shinjiro Hino, Woojin Kang, Kenji Miyado, Mitsuyoshi Nakao, Masayuki Miura, Satoru Kobayashi, Masakazu Namihira
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract Tissue aging is a major cause of aging-related disabilities and a shortened life span. Understanding how tissue aging progresses and identifying the factors underlying tissue aging are crucial; however, the mechanism of tissue aging is not f
Externí odkaz:
https://doaj.org/article/05e309c3bbee4546af40f1bf690393d7
Autor:
Hirotaka Araki, Shinjiro Hino, Kotaro Anan, Kanji Kuribayashi, Kan Etoh, Daiki Seko, Ryuta Takase, Kensaku Kohrogi, Yuko Hino, Yusuke Ono, Eiichi Araki, Mitsuyoshi Nakao
Publikováno v:
eLife, Vol 12 (2023)
Skeletal muscle exhibits remarkable plasticity in response to environmental cues, with stress-dependent effects on the fast-twitch and slow-twitch fibers. Although stress-induced gene expression underlies environmental adaptation, it is unclear how t
Externí odkaz:
https://doaj.org/article/7d544e7157754546a4cf4b608bded09c
Autor:
Takuro Horii, Sumiyo Morita, Shinjiro Hino, Mika Kimura, Yuko Hino, Hiroshi Kogo, Mitsuyoshi Nakao, Izuho Hatada
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-17 (2020)
Abstract Background Epigenetic modifications, including DNA methylation, play an important role in gene silencing and genome stability. Consequently, epigenetic dysregulation can cause several diseases, such as cancer, obesity, diabetes, autism, and
Externí odkaz:
https://doaj.org/article/ddbaf52b3f00427c813f81dfb8ab45b8
Autor:
Yoko Yasuda, Kazuaki Tokunaga, Tomoaki Koga, Chiyomi Sakamoto, Ilya G. Goldberg, Noriko Saitoh, Mitsuyoshi Nakao
Publikováno v:
Cancer Medicine, Vol 9, Iss 6, Pp 2223-2234 (2020)
Abstract Biological morphologies of cells and tissues represent their physiological and pathological conditions. The importance of quantitative assessment of morphological information has been highly recognized in clinical diagnosis and therapeutic s
Externí odkaz:
https://doaj.org/article/19207ab5a9f34cebb7d93f626d7556b8
Autor:
Masayuki Kusakabe, Erina Kakumu, Fumika Kurihara, Kazuki Tsuchida, Takumi Maeda, Haruto Tada, Kanako Kusao, Akari Kato, Takeshi Yasuda, Tomonari Matsuda, Mitsuyoshi Nakao, Masayuki Yokoi, Wataru Sakai, Kaoru Sugasawa
Publikováno v:
iScience, Vol 25, Iss 4, Pp 104040- (2022)
Summary: The XPC protein complex plays a central role in DNA lesion recognition for global genome nucleotide excision repair (GG-NER). Lesion recognition can be accomplished in either a UV-DDB-dependent or -independent manner; however, it is unclear
Externí odkaz:
https://doaj.org/article/6a9067f664a44449b7507f62bceb667c
Autor:
Yasuharu Kanki, Masashi Muramatsu, Yuri Miyamura, Kenta Kikuchi, Yoshiki Higashijima, Ryo Nakaki, Jun-ichi Suehiro, Yuji Sasaki, Yoshiaki Kubota, Haruhiko Koseki, Hiroshi Morioka, Tatsuhiko Kodama, Mitsuyoshi Nakao, Daisuke Kurotaki, Hiroyuki Aburatani, Takashi Minami
Publikováno v:
Cell Reports, Vol 38, Iss 6, Pp 110332- (2022)
Summary: Endothelial cells (ECs) are phenotypically heterogeneous, mainly due to their dynamic response to the tissue microenvironment. Vascular endothelial cell growth factor (VEGF), the best-known angiogenic factor, activates calcium-nuclear factor
Externí odkaz:
https://doaj.org/article/f411c484c43e4225a1c493fc22d5bc0b
Autor:
Tomoka Igata, Hiroshi Tanaka, Kan Etoh, Seonghyeon Hong, Naoki Tani, Tomoaki Koga, Mitsuyoshi Nakao
Publikováno v:
PLoS ONE, Vol 17, Iss 1, p e0262488 (2022)
Cellular senescence is accompanied by metabolic and epigenomic remodeling, but the transcriptional mechanism of this process is unclear. Our previous RNA interference-based screen of chromatin factors found that lysine methyltransferases including SE
Externí odkaz:
https://doaj.org/article/5180f5d780a54889947538e4cec12706