Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Mitsuyo Hirota"'
Autor:
Akio Suzuki, Masayuki Akimoto, Izumi Iida, Takashi Ishizaki, Masayoshi Tani, Mitsuyo Hirota, Toshio Suwa, Shohei Higuchi, Kan Chiba
Publikováno v:
Drug Metabolism and Pharmacokinetics. 18:104-113
To clarify whether CYP2C19 is involved in the overall metabolism of clarithromycin (CAM) or not, in vitro studies using human liver microsomes and recombinant CYPs were performed by an approach based on the disappearance rate of parent compound from
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bedd32eecb67cc334e8955e001605c97
https://doi.org/10.2133/dmpk.18.104
https://doi.org/10.2133/dmpk.18.104
Autor:
Kaoru Kobayashi, Kan Chiba, Izumi Iida, Mitsuyo Hirota, Atsunori Miyata, Masayuki Akimoto, Shohei Higuchi, Masayuki Arai
Publikováno v:
Drug Metabolism and Disposition. 32:7-9
The effects of allelic variants of CYP2C9 ( CYP2C9*2 and CYP2C9*3 ) on lornoxicam 5′-hydroxylation were studied using the corresponding variant protein expressed in baculovirus-infected insect cells and human liver microsomes of known genotypes of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a88b08e4792258818e16877ecd9cfaab
https://doi.org/10.1124/dmd.32.1.7
https://doi.org/10.1124/dmd.32.1.7