Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Mitsuyasu Nakamura"'
Autor:
Masaaki Higashiyama, Ryota Hokari, Toshihide Ueda, Mitsuyasu Nakamura, Yoshikiyo Okada, Chie Kurihara, A. Kawaguchi, Chikako Watanabe, Syunsuke Komoto, S. Miura, Shigeaki Nagao
Publikováno v:
Clinical and Experimental Immunology. 162:156-162
SummaryThe aim of this study was to investigate the effect of interferon (IFN)-α on recruitment of platelets and monocytes within the murine small intestinal venular endothelium. Monocytes were isolated from bone marrow of C57B6 mice. Platelets were
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ad7ca1ad6cae36ab2fc515e468d5805
https://doi.org/10.1111/j.1365-2249.2010.04222.x
https://doi.org/10.1111/j.1365-2249.2010.04222.x
Autor:
Masaaki Higashiyama, Hisayuki Matsunaga, Chikako Watanabe, Yoshikiyo Okada, Chie Kurihara, Shunsuke Komoto, Mitsuyasu Nakamura, Shigeaki Nagao, Atsushi Kawaguchi, Soichiro Miura, Ryota Hokari
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 297:G1077-G1084
Excessive migration of monocytes to a site of intestinal inflammation contributes to tissue damage in Crohn's disease. It is known that cilostazol, a specific phosphodiesterase-3 (PDE-3) inhibitor of platelets, decreases monocyte recruitment to intes
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db7166270309aeba4db18aab75dae419
https://doi.org/10.1152/ajpgi.00240.2009
https://doi.org/10.1152/ajpgi.00240.2009
Autor:
Chie Kurihara, Mitsuyasu Nakamura, Soichiro Miura, Hisayuki Matsunaga, Yoshikiyo Okada, Koichi Takebayashi, Shigeaki Nagao, Chikako Watanabe, Keisuke Okudaira, Kazuro Itoh, Yoshikazu Tsuzuki, Ryota Hokari, Syunsuke Komoto, A. Kawaguchi
Publikováno v:
Inflammatory Bowel Diseases. 14:1348-1357
Background: Although the immunoregulatory effects of ω-3 fatty acid and adiponectin have been postulated, their role in intestinal inflammation is controversial. The aim of this study was to determine whether dietary fat intake influences activity o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::622a2d90bce260a5e89f034a40fdb761
https://doi.org/10.1002/ibd.20491
https://doi.org/10.1002/ibd.20491
Publikováno v:
Proceedings of the National Academy of Sciences. 102:18159-18164
The retinoblastoma tumor-suppressor protein (Rb) plays a critical role in controlling cellular proliferation and apoptosis by regulating E2F transcription factors. Rb is a key target of oncoproteins expressed by DNA tumor viruses, but RNA viruses are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::74febc44b18a09cba0fe9b4eeaa25b03
https://doi.org/10.1073/pnas.0505605102
https://doi.org/10.1073/pnas.0505605102
Autor:
Masanori Ikeda, Mitsuyasu Nakamura, Michael Gale, Kui Li, Josephine C. Ferreon, Allan Chris M. Ferreon, Eileen Foy, Stanley M. Lemon, Stuart C. Ray
Publikováno v:
Proceedings of the National Academy of Sciences. 102:2992-2997
Toll-like receptors (TLRs) bind pathogen-specific ligands early in infection, initiating signaling pathways that lead to expression of multiple protective cellular genes. Many viruses have evolved strategies that block the effector mechanisms induced
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cb3fb4738ccb0f9458cbc7ae7400b1a
https://doi.org/10.1073/pnas.0408824102
https://doi.org/10.1073/pnas.0408824102
Autor:
Yoshihisa Oguchi, Yoshimasa Saito, Mitsuyasu Nakamura, Hiromasa Ishii, Hiroshi Nagata, Tamako Takagi, Hirotoshi Ebinuma, Yasutaka Inagaki, Hiroshi Katsura, Kanji Wakabayashi, Hidetsugu Saito
Publikováno v:
Liver. 21:192-197
BACKGROUND/AIMS The development of retinal lesions induced by a uniform regimen of interferon-alpha therapy for chronic hepatitis C was prospectively investigated. METHODS Eighty-one patients received 6 mega units of natural interferon-alpha intramus
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e8086c525d1177aeb1624489c4fd5ba7
https://doi.org/10.1034/j.1600-0676.2001.021003192.x
https://doi.org/10.1034/j.1600-0676.2001.021003192.x
Autor:
Yoshimasa Saito, Kanji Wakabayashi, Hidetsugu Saito, Hirotoshi Ebinuma, Tamako Takagi, Mitsuyasu Nakamura, Hiromasa Ishii, Nobuhiro Nakamoto
Publikováno v:
Journal of Cellular Physiology. 187:392-401
The presence of telomerase has been demonstrated recently in many different malignancies. Several reports documented that in human hepatocellular carcinoma, the level of telomerase activity parallels its differentiation stage. In the present study, t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fa69b4e7ff7f878b43e8decc3d1035f6
https://doi.org/10.1002/jcp.1087
https://doi.org/10.1002/jcp.1087
Autor:
Makoto Suematsu, Atsushi Kawaguchi, Chikako Watanabe, Soichiro Miura, Yoshikiyo Okada, Hideaki Hozumi, Chie Kurihara, Nobuhito Goda, Mitsuyasu Nakamura, Masaaki Higashiyama, Toshihide Ueda, Shunsuke Komoto, Ryota Hokari, Shigeaki Nagao, Kengo Tomita
Publikováno v:
Journal of leukocyte biology. 91(6)
HIF-1 is active in hypoxia, such as inflamed mucosa, and HIF-1 in epithelium has been reported to control inflamed mucosa in IBD models. Although T cells play an important role for pathogenesis of IBD, the function of HIF-1 in T cells remains to be e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dce0d06b17be415546cc223fad9f3ac3
https://pubmed.ncbi.nlm.nih.gov/22457366
https://pubmed.ncbi.nlm.nih.gov/22457366
Autor:
Shunsuke Komoto, Atsuo Sekiyama, Chie Kurihara, Yoshikiyo Okada, Hideaki Hozumi, Hisayuki Matsunaga, Masaaki Higashiyama, Mitsuyasu Nakamura, Chikako Watanabe, Soichiro Miura, Toshihide Ueda, Atsushi Kawaguchi, Ryota Hokari, Shigeaki Nagao
Publikováno v:
American journal of physiology. Gastrointestinal and liver physiology. 301(3)
Psychological stress is an environmental factor considered to be a precipitating factor of inflammatory bowel disease. Interleukin (IL)-18 plays a role in stress-induced aggravation in some diseases. The aim of this study was to establish a model of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9f8a4e9751fa8c9087784c7137f21693
https://pubmed.ncbi.nlm.nih.gov/21719737
https://pubmed.ncbi.nlm.nih.gov/21719737
Autor:
Mitsuyasu Nakamura, Masanori Ikeda, Toshifumi Hibi, Hidetsugu Saito, Soichiro Miura, Ryota Hokari, Nobuyuki Kato
AIM: To elucidate the effect of antioxidants, resveratrol (RVT) and astaxanthin (AXN), on hepatitis C virus (HCV) replication. METHODS: We investigated the effect of recent popular antioxidant supplements on replication of the HCV replicon system OR6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19cc3d49fbe57bcf50e16dbb8c47ec19
https://europepmc.org/articles/PMC2806556/
https://europepmc.org/articles/PMC2806556/
