Zobrazeno 1 - 10
of 66
pro vyhledávání: '"Mitsuyasu Nakamura"'
Publikováno v:
In Hepatology 2001 34(4) Part 2:A618-A618
Publikováno v:
In Hepatology 2001 34(4) Part 2:A435-A435
Autor:
Masaaki Higashiyama, Ryota Hokari, Toshihide Ueda, Mitsuyasu Nakamura, Yoshikiyo Okada, Chie Kurihara, A. Kawaguchi, Chikako Watanabe, Syunsuke Komoto, S. Miura, Shigeaki Nagao
Publikováno v:
Clinical and Experimental Immunology. 162:156-162
SummaryThe aim of this study was to investigate the effect of interferon (IFN)-α on recruitment of platelets and monocytes within the murine small intestinal venular endothelium. Monocytes were isolated from bone marrow of C57B6 mice. Platelets were
Autor:
Masaaki Higashiyama, Hisayuki Matsunaga, Chikako Watanabe, Yoshikiyo Okada, Chie Kurihara, Shunsuke Komoto, Mitsuyasu Nakamura, Shigeaki Nagao, Atsushi Kawaguchi, Soichiro Miura, Ryota Hokari
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 297:G1077-G1084
Excessive migration of monocytes to a site of intestinal inflammation contributes to tissue damage in Crohn's disease. It is known that cilostazol, a specific phosphodiesterase-3 (PDE-3) inhibitor of platelets, decreases monocyte recruitment to intes
Autor:
Chie Kurihara, Mitsuyasu Nakamura, Soichiro Miura, Hisayuki Matsunaga, Yoshikiyo Okada, Koichi Takebayashi, Shigeaki Nagao, Chikako Watanabe, Keisuke Okudaira, Kazuro Itoh, Yoshikazu Tsuzuki, Ryota Hokari, Syunsuke Komoto, A. Kawaguchi
Publikováno v:
Inflammatory Bowel Diseases. 14:1348-1357
Background: Although the immunoregulatory effects of ω-3 fatty acid and adiponectin have been postulated, their role in intestinal inflammation is controversial. The aim of this study was to determine whether dietary fat intake influences activity o
Publikováno v:
Proceedings of the National Academy of Sciences. 102:18159-18164
The retinoblastoma tumor-suppressor protein (Rb) plays a critical role in controlling cellular proliferation and apoptosis by regulating E2F transcription factors. Rb is a key target of oncoproteins expressed by DNA tumor viruses, but RNA viruses are
Autor:
Masanori Ikeda, Mitsuyasu Nakamura, Michael Gale, Kui Li, Josephine C. Ferreon, Allan Chris M. Ferreon, Eileen Foy, Stanley M. Lemon, Stuart C. Ray
Publikováno v:
Proceedings of the National Academy of Sciences. 102:2992-2997
Toll-like receptors (TLRs) bind pathogen-specific ligands early in infection, initiating signaling pathways that lead to expression of multiple protective cellular genes. Many viruses have evolved strategies that block the effector mechanisms induced
Autor:
Yoshihisa Oguchi, Yoshimasa Saito, Mitsuyasu Nakamura, Hiromasa Ishii, Hiroshi Nagata, Tamako Takagi, Hirotoshi Ebinuma, Yasutaka Inagaki, Hiroshi Katsura, Kanji Wakabayashi, Hidetsugu Saito
Publikováno v:
Liver. 21:192-197
BACKGROUND/AIMS The development of retinal lesions induced by a uniform regimen of interferon-alpha therapy for chronic hepatitis C was prospectively investigated. METHODS Eighty-one patients received 6 mega units of natural interferon-alpha intramus
Autor:
Yoshimasa Saito, Kanji Wakabayashi, Hidetsugu Saito, Hirotoshi Ebinuma, Tamako Takagi, Mitsuyasu Nakamura, Hiromasa Ishii, Nobuhiro Nakamoto
Publikováno v:
Journal of Cellular Physiology. 187:392-401
The presence of telomerase has been demonstrated recently in many different malignancies. Several reports documented that in human hepatocellular carcinoma, the level of telomerase activity parallels its differentiation stage. In the present study, t
Autor:
Makoto Suematsu, Atsushi Kawaguchi, Chikako Watanabe, Soichiro Miura, Yoshikiyo Okada, Hideaki Hozumi, Chie Kurihara, Nobuhito Goda, Mitsuyasu Nakamura, Masaaki Higashiyama, Toshihide Ueda, Shunsuke Komoto, Ryota Hokari, Shigeaki Nagao, Kengo Tomita
Publikováno v:
Journal of leukocyte biology. 91(6)
HIF-1 is active in hypoxia, such as inflamed mucosa, and HIF-1 in epithelium has been reported to control inflamed mucosa in IBD models. Although T cells play an important role for pathogenesis of IBD, the function of HIF-1 in T cells remains to be e