Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mitsutoshi Iimura"'
Publikováno v:
Cellular Microbiology. 8:869-879
Enterohaemorrhagic Escherichia coli O157:H7 (EHEC) is a clinically important foodborne pathogen that colonizes human colon epithelium and induces acute colonic inflammation, but does not invade the epithelial cells. Whereas Shiga toxin (Stx) and bact
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b588ec6c4b2ef194f45bf104dbb5ba5
https://doi.org/10.1111/j.1462-5822.2005.00673.x
https://doi.org/10.1111/j.1462-5822.2005.00673.x
Autor:
Kikuji Itoh, Hiroyuki Takatsu, Sayaka Ohshima, Risa Chihara, Mitsutoshi Iimura, Hiroshi Ohno, Kazuya Kawano, Takeshi Shimaoka, Kimiyo Hamura, Koji Hase, Takaya Murakami, Shin Yonehara
Publikováno v:
The Journal of Immunology. 176:43-51
The recently identified CXCL16 has dual functions as a transmembrane adhesion molecule and a soluble chemokine. In this study we found that CXCL16 mRNA and protein were expressed constitutively on the follicle-associated epithelium covering Peyer’s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c899501e4a1cfd6f68138a40f01119
https://doi.org/10.4049/jimmunol.176.1.43
https://doi.org/10.4049/jimmunol.176.1.43
Autor:
Martin F. Kagnoff, Yukiko Miyamoto, Lars Eckmann, Kouji Hase, Richard L. Gallo, Mitsutoshi Iimura
Publikováno v:
The Journal of Immunology. 174:4901-4907
Cathelicidin-related antimicrobial peptide (mCRAMP), the sole murine cathelicidin, is encoded by the gene Cnlp. We show that mCRAMP expression in the intestinal tract is largely restricted to surface epithelial cells in the colon. Synthetic mCRAMP ha
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a9ed453b27c6a9a263ecca219b4f6e
https://doi.org/10.4049/jimmunol.174.8.4901
https://doi.org/10.4049/jimmunol.174.8.4901
Autor:
Michael Karin, Martin F. Kagnoff, Hongjun Liu, Shin Maeda, Laurie A. Bankston, Mitsutoshi Iimura, Lars Eckmann, Li-Chung Hsu
Publikováno v:
Science. 307:734-738
Variants of NOD2, an intracellular sensor of bacteria-derived muramyl dipeptide (MDP), increase susceptibility to Crohn's disease (CD). These variants are thought to be defective in activation of nuclear factor κB (NF-κB) and antibacterial defenses
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6493532d85be6d580e02871616201679
https://doi.org/10.1126/science.1103685
https://doi.org/10.1126/science.1103685
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 287:G1062-G1069
The chemokine CCL28 is constitutively expressed by epithelial cells at several mucosal sites and is thought to function as a homeostatic chemoattractant of subpopulations of T cells and IgA B cells and to mediate antimicrobial activity. We report her
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::da69d534eed1f6377320155e33b478ad
https://doi.org/10.1152/ajpgi.00162.2004
https://doi.org/10.1152/ajpgi.00162.2004
Autor:
Masamoto Murakami, Lars Eckmann, Martin F. Kagnoff, Richard L. Gallo, Mitsutoshi Iimura, Sheri P. Cole, Marygorret Obonyo, Takaaki Ohtake, Yoshimune Horibe, Koji Hase
Publikováno v:
Gastroenterology. 125:1613-1625
Background & Aims: LL-37/human cationic antimicrobial peptide 18 (hCAP18) is a human cathelicidin with broad-spectrum antimicrobial, lipopolysaccharide binding, and chemotactic activities. This study examined the role of LL-37/hCAP18 in gastric innat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f4b494405d7fd82c6bd9d7cc888a77e2
https://doi.org/10.1053/j.gastro.2003.08.028
https://doi.org/10.1053/j.gastro.2003.08.028
Publikováno v:
The American Journal of Gastroenterology. 97:2820-2828
OBJECTIVE: The aim of this study was to clarify the correlation between cytokine profile in colonic mucosa with disease activity and response to granulocytapheresis (GCAP) in patients with ulcerative colitis (UC), using a reliable, reproducible quant
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5a98ffaee1d322be0b05ed4fe8acf2c6
https://doi.org/10.1111/j.1572-0241.2002.07029.x
https://doi.org/10.1111/j.1572-0241.2002.07029.x
Autor:
Koji Hase, Takaya Murakami, Mitsutoshi Iimura, Gemilson Soares Pontes, Sayaka Kawano, Hiroshi Kiyono, Shunsuke Kimura, Shin Ichi Fukuoka, Kimiyo Hamura, Atsuko Yabashi, Masashi Ebisawa, Kazuya Kawano, Satoshi Waguri, Kazunori Kadokura, Hiroshi Ohno, Gaku Nakato, Anson W. Lowe, Shinji Fukuda, Kikuji Itoh, Yumiko Fujimura, Tomonori Nochi, Toru Tobe
Publikováno v:
Nature. 462(7270)
The mucosal immune system forms the largest part of the entire immune system, containing about three-quarters of all lymphocytes and producing grams of secretory IgA daily to protect the mucosal surface from pathogens. To evoke the mucosal immune res
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2a4d65620fffc3bbfdeea01fc6b29bb
https://pubmed.ncbi.nlm.nih.gov/20353296
https://pubmed.ncbi.nlm.nih.gov/20353296
Autor:
Mitsutoshi Iimura, Martina E. Spehlmann, Koji Hase, Lillian J. Choi, Dustin Hammond, Elaine M. Hanson, Sara M. Dann, Lars Eckmann
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 180(10)
Enteric infections with attaching/effacing lesion-inducing bacterial pathogens are a worldwide health problem. A murine infection model with one such pathogen, Citrobacter rodentium, was used to elucidate the importance of the pleiotropic immune regu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8ce3ff5cdbb70ec011850b096eae04eb
https://pubmed.ncbi.nlm.nih.gov/18453602
https://pubmed.ncbi.nlm.nih.gov/18453602
[A case of Turner syndrome complicated with Crohn's disease, erythema nodosum and Hashimoto disease]
Autor:
Haruka, Noto, Mitsutoshi, Iimura, Toyohiko, Karibe, Maria, Tanishima, Kimiyo, Hamura, Tomoko, Takasaki, Naoko, Mochizuki, Nobuyuki, Torii, Bun-ei, Iizuka, Keiko, Shiratori
Publikováno v:
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology. 103(9)
A 26-year-old woman, who had had Turner syndrome from age 10 years old, had diarrhea, fever, joint pain, and erythema in the lower left leg. She was given a diagnosis of Crohn's disease, erythema nodosum, and Hashimoto disease. Systemic steroid thera
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::13b5374111d56b5f9ae50b883bb9e93c
https://pubmed.ncbi.nlm.nih.gov/16953100
https://pubmed.ncbi.nlm.nih.gov/16953100