Zobrazeno 1 - 10
of 59
pro vyhledávání: '"Mitsuru Sada"'
Autor:
Fumi Kobayashi, Takeshi Saraya, Takatora Akizawa, Taro Abe, Ryo Takagi, Eriko Ieki, Narishige Ishikawa, Nozomi Kurokawa, Jumpei Aso, Hiroki Nunokawa, Yasuo Nakamoto, Manabu Ishida, Mitsuru Sada, Keitaro Nakamoto, Saori Takata, Haruyuki Ishii
Publikováno v:
Journal of Clinical Medicine, Vol 13, Iss 2, p 347 (2024)
Bronchoscopy is an invasive procedure, and patient coughing during examination has been reported to cause patient distress. This study aimed to clarify the relationship between cough severity and diagnostic yield of endobronchial ultrasonography with
Externí odkaz:
https://doaj.org/article/e4a97b3035c84972b046aa0d0daff0e4
Autor:
Takashi Ono, Koichi Hashimoto, Yohei Kume, Mina Chishiki, Hisao Okabe, Masatoki Sato, Sakurako Norito, Jumpei Aso, Mitsuru Sada, Izumi Mochizuki, Fumi Mashiyama, Naohisa Ishibashi, Shigeo Suzuki, Hiroko Sakuma, Reiko Suwa, Miyuki Kawase, Makoto Takeda, Kazuya Shirato, Hirokazu Kimura, Mitsuaki Hosoya
Publikováno v:
Microbiology Spectrum, Vol 11, Iss 4 (2023)
ABSTRACT Human respiratory syncytial viruses (HRSVs) are divided into subgroups A and B, which are further divided based on the nucleotide sequence of the second hypervariable region (HVR) of the attachment glycoprotein (G) gene. Understanding the mo
Externí odkaz:
https://doaj.org/article/514640e3cf6f4f7fa072dfe55b00b2d9
Autor:
Norika Nagasawa, Ryusuke Kimura, Mao Akagawa, Tatsuya Shirai, Mitsuru Sada, Kaori Okayama, Yuka Sato-Fujimoto, Makoto Saito, Mayumi Kondo, Kazuhiko Katayama, Akihide Ryo, Makoto Kuroda, Hirokazu Kimura
Publikováno v:
Microorganisms, Vol 11, Iss 9, p 2336 (2023)
To better understand the evolution of the SARS-CoV-2 Omicron subvariants, we performed molecular evolutionary analyses of the spike (S) protein gene/S protein using advanced bioinformatics technologies. First, time-scaled phylogenetic analysis estima
Externí odkaz:
https://doaj.org/article/8728f7d88448447f8dd6a77c4d21213d
Autor:
Tomoko Takahashi, Ryusuke Kimura, Tatsuya Shirai, Mitsuru Sada, Toshiyuki Sugai, Kosuke Murakami, Kazuhiko Harada, Kazuto Ito, Yuki Matsushima, Fuminori Mizukoshi, Kaori Okayama, Yuriko Hayashi, Mayumi Kondo, Tsutomu Kageyama, Yoshiyuki Suzuki, Haruyuki Ishii, Akihide Ryo, Kazuhiko Katayama, Kiyotaka Fujita, Hirokazu Kimura
Publikováno v:
Viruses, Vol 15, Iss 7, p 1497 (2023)
To understand the evolution of GII.P6-GII.6 and GII.P7-GII.6 strains, the prevalent human norovirus genotypes, we analysed both the RdRp region and VP1 gene in globally collected strains using authentic bioinformatics technologies. A common ancestor
Externí odkaz:
https://doaj.org/article/6050a637c68d4be98c9012b66d2cc825
Autor:
Mitsuru Sada, Masato Watanabe, Toshiya Inui, Keitaro Nakamoto, Aya Hirata, Masuo Nakamura, Kojiro Honda, Takeshi Saraya, Daisuke Kurai, Hirokazu Kimura, Haruyuki Ishii, Hajime Takizawa
Publikováno v:
Immunity, Inflammation and Disease, Vol 9, Iss 2, Pp 363-373 (2021)
Abstract Rationale Severe eosinophilic asthma is characterized by airway eosinophilia and corticosteroid‐resistance, commonly overlapping with type 2 inflammation. It has been reported that chemokine (C‐C motif) ligand 5 (CCL5) is involved in the
Externí odkaz:
https://doaj.org/article/bd05412564024564950acd0828a6a6b4
Autor:
Tatsuya Shirai, Mao Akagawa, Miho Makino, Manami Ishii, Ayaka Arai, Norika Nagasawa, Mitsuru Sada, Ryusuke Kimura, Kaori Okayama, Taisei Ishioka, Haruyuki Ishii, Shinichiro Hirai, Akihide Ryo, Haruyoshi Tomita, Hirokazu Kimura
Publikováno v:
Microorganisms, Vol 11, Iss 3, p 635 (2023)
Despite the increasing evidence of the clinical impact of Pseudomonas-derived cephalosporinase (PDC) sequence polymorphisms, the molecular evolution of its encoding gene, blaPDC, remains elusive. To elucidate this, we performed a comprehensive evolut
Externí odkaz:
https://doaj.org/article/45a6945b25bd44bf9e1cd2b06483dfc4
Autor:
Yuriko Hayashi, Mitsuru Sada, Tatsuya Shirai, Kaori Okayama, Ryusuke Kimura, Mayumi Kondo, Mitsuaki Okodo, Takeshi Tsugawa, Akihide Ryo, Hirokazu Kimura
Publikováno v:
Viruses, Vol 14, Iss 12, p 2616 (2022)
While the aetiology of asthma is unclear, the onset and/or exacerbation of asthma may be associated with respiratory infections. Virus-induced asthma is also known as virus-associated/triggered asthma, and the reported main causative agent is rhinovi
Externí odkaz:
https://doaj.org/article/16c9c51d5a2a417fa911eabca9a79965
Autor:
Mao Akagawa, Tatsuya Shirai, Mitsuru Sada, Norika Nagasawa, Mayumi Kondo, Makoto Takeda, Koo Nagasawa, Ryusuke Kimura, Kaori Okayama, Yuriko Hayashi, Toshiyuki Sugai, Takeshi Tsugawa, Haruyuki Ishii, Hisashi Kawashima, Kazuhiko Katayama, Akihide Ryo, Hirokazu Kimura
Publikováno v:
Viruses, Vol 14, Iss 11, p 2382 (2022)
Molecular interactions between respiratory syncytial virus (RSV) fusion protein (F protein) and the cellular receptor Toll-like receptor 4 (TLR4) and myeloid differentiation factor-2 (MD-2) protein complex are unknown. Thus, to reveal the detailed mo
Externí odkaz:
https://doaj.org/article/d167ac91160a426ba0477bb359765584
Autor:
Mitsuru Sada, Hirokazu Kimura, Norika Nagasawa, Mao Akagawa, Kaori Okayama, Tatsuya Shirai, Soyoka Sunagawa, Ryusuke Kimura, Takeshi Saraya, Haruyuki Ishii, Daisuke Kurai, Takeshi Tsugawa, Atsuyoshi Nishina, Haruyoshi Tomita, Mitsuaki Okodo, Shinichiro Hirai, Akihide Ryo, Taisei Ishioka, Koichi Murakami
Publikováno v:
Microorganisms, Vol 10, Iss 8, p 1660 (2022)
DNA gyrase plays important roles in genome replication in various bacteria, including Pseudomonasaeruginosa. The gyrA gene encodes the gyrase subunit A protein (GyrA). Mutations in GyrA are associated with resistance to quinolone-based antibiotics. W
Externí odkaz:
https://doaj.org/article/9df7d726392a4c89bf2dac1cec76f460
Autor:
Tatsuya Shirai, Mitsuru Sada, Takeshi Saraya, Daisuke Kurai, Soyoka Sunagawa, Haruyuki Ishii, Hirokazu Kimura
Publikováno v:
Viruses, Vol 14, Iss 2, p 338 (2022)
There are currently no antiviral agents for human metapneumovirus (HMPV), respiratory syncytial virus (RSV), mumps virus (MuV), or measles virus (MeV). Favipiravir has been developed as an anti-influenza agent, and this agent may be effective against
Externí odkaz:
https://doaj.org/article/55c58e39ce2846aea1e53977a0ca5adf