Zobrazeno 1 - 10
of 95
pro vyhledávání: '"Mitsuru Haniu"'
Autor:
Richard L. Kendall, Angela Coxon, Ke Zhang, Todd Juan, Will F. Barron, Mitsuru Haniu, Qing Chen, Gary Elliott, Jilin Sun, Trace S. Tsuruda, Susanne Meyer, Jan Sun, Teresa L. Burgess
Supplementary Tables 1-2 from Biochemical Characterization of AMG 102: A Neutralizing, Fully Human Monoclonal Antibody to Human and Nonhuman Primate Hepatocyte Growth Factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f6715e7b0d0bb74d81799d869a93b53a
https://doi.org/10.1158/1535-7163.22485368
https://doi.org/10.1158/1535-7163.22485368
Autor:
Richard L. Kendall, Angela Coxon, Ke Zhang, Todd Juan, Will F. Barron, Mitsuru Haniu, Qing Chen, Gary Elliott, Jilin Sun, Trace S. Tsuruda, Susanne Meyer, Jan Sun, Teresa L. Burgess
AMG 102 is a fully human monoclonal antibody that selectively targets and neutralizes hepatocyte growth factor/scatter factor (HGF/SF). A detailed biochemical and functional characterization of AMG 102 was done to support its clinical development for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0fbd342a8b9ca6f6c7e617124bd6740e
https://doi.org/10.1158/1535-7163.c.6531908.v1
https://doi.org/10.1158/1535-7163.c.6531908.v1
Autor:
Richard L. Kendall, Angela Coxon, Ke Zhang, Todd Juan, Will F. Barron, Mitsuru Haniu, Qing Chen, Gary Elliott, Jilin Sun, Trace S. Tsuruda, Susanne Meyer, Jan Sun, Teresa L. Burgess
Supplementary Figure 1 from Biochemical Characterization of AMG 102: A Neutralizing, Fully Human Monoclonal Antibody to Human and Nonhuman Primate Hepatocyte Growth Factor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08727ae46c999050261d952c685c557b
https://doi.org/10.1158/1535-7163.22485374.v1
https://doi.org/10.1158/1535-7163.22485374.v1
Autor:
Banghua Sun, Wei Fan, Aldona Balciunas, Jillian K. Cooper, Gal Bitan, Shirley Steavenson, Paul E. Denis, Yunjen Young, Beverly Adler, Larry Daugherty, Raffi Manoukian, Gary Elliott, Wenyan Shen, Jane Talvenheimo, David B. Teplow, Mitsuru Haniu, Raj Haldankar, Jette Wypych, Christopher A. Ross, Martin Citron, William G. Richards
Publikováno v:
Neurobiology of Disease, Vol 11, Iss 1, Pp 111-122 (2002)
Amino-terminal fragments of huntingtin, which contain the expanded polyglutamine repeat, have been proposed to contribute to the pathology of Huntington's disease (HD). Data supporting this claim have been generated from patients with HD in which tru
Externí odkaz:
https://doaj.org/article/26fbad44ea784ee88e89c01dad9e7cb5
Autor:
Chris Spahr, Hsieng Sen Lu, William G. Richards, Ching Chen, Mitsuru Haniu, Wei Fan, Tom Horan, John O. Hui
Publikováno v:
Protein Science. 20:1802-1813
Human Dickkopf-1 (huDKK1), an inhibitor of the canonical Wnt-signaling pathway that has been implicated in bone metabolism and other diseases, was expressed in engineered Chinese hamster ovary cells and purified. HuDKK1 is biologically active in a TC
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::510587ad3eafa0829d732639d18fb1ba
https://doi.org/10.1002/pro.705
https://doi.org/10.1002/pro.705
Autor:
Qing Chen, Jan Sun, Ke Zhang, Angela Coxon, Trace Tsuruda, Teresa L. Burgess, Will F. Barron, Susanne Meyer, Todd Juan, Jilin Sun, Richard Kendall, Gary Elliott, Mitsuru Haniu
Publikováno v:
Molecular Cancer Therapeutics. 9:400-409
AMG 102 is a fully human monoclonal antibody that selectively targets and neutralizes hepatocyte growth factor/scatter factor (HGF/SF). A detailed biochemical and functional characterization of AMG 102 was done to support its clinical development for
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9782b6bb59e211b276c384aa59d125bc
https://doi.org/10.1158/1535-7163.mct-09-0824
https://doi.org/10.1158/1535-7163.mct-09-0824
Autor:
Robert A. Rosenfeld, Mitsuru Haniu, Kendall Stoney, James A. Miller, Christine Acklin, Michael F. Rohde
Publikováno v:
International Journal of Peptide and Protein Research. 41:548-552
Three disulfide linkages of recombinant human brain-derived neurotrophic factor (BDNF) were determined by peptide sequence analysis and characterized by mass spectrometry. The three disulfide bonds for BDNF expressed in Chinese hamster ovary cells in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90e1ac1e59b6c8576321d9fb960469fb
https://doi.org/10.1111/j.1399-3011.1993.tb00476.x
https://doi.org/10.1111/j.1399-3011.1993.tb00476.x
Autor:
Viswanatham Katta, Steven Kahn, Teresa L. Burgess, Robert Vassar, Paul Denis, Elizabeth A. Mendiaz, Martin Citron, Gary Rogers, Janis Fuller, Brian D. Bennett, Sandra Ross, Yunjen Young, Mitsuru Haniu, John O. Hui
Publikováno v:
Journal of Biological Chemistry. 275:21099-21106
The cerebral deposition of amyloid beta-peptide is an early and critical feature of Alzheimer's disease. Amyloid beta-peptide is released from the amyloid precursor protein by the sequential action of two proteases, beta-secretase and gamma-secretase
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f550e414f8487a5d2446f1dfa591678e
https://doi.org/10.1074/jbc.m002095200
https://doi.org/10.1074/jbc.m002095200
Autor:
Jones T, Brian D. Bennett, Yunjen Young, Jingwen Zhang, Mitsuru Haniu, Thomas J. Zamborelli, Mark A. Jarosinski, Dodson Ws, Douglas M. Lenz, Bennet J. Harding, Chuan-Fa Liu
Publikováno v:
The Journal of Peptide Research. 55:359-371
The 52-residue alpha/beta chimera of the epidermal growth factor-like domain in neu differentiation factor (NDFealpha/beta) has been synthesized and folded to form a three disulfide bridge (Cys182-Cys196, Cys190-Cys210, Cys212-Cys221) containing pept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28ed17cf8a4005a9b68ffd21a6b1e1a6
https://doi.org/10.1034/j.1399-3011.2000.00672.x
https://doi.org/10.1034/j.1399-3011.2000.00672.x
Publikováno v:
The Journal of Peptide Research. 54:514-521
We have assigned the disulfide structure of Md-65 agouti-related protein (Md65-AGRP) using differential reduction and alkylation followed by direct sequencing analysis. The mature human AGRP is a single polypeptide chain of 112 amino acid residues, c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::841d48cdb6eeaeaf5ae20669eadfb854
https://doi.org/10.1034/j.1399-3011.1999.00126.x
https://doi.org/10.1034/j.1399-3011.1999.00126.x