Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Mitsuo Sakato"'
Autor:
Naoto Tadano, Sachio Morimoto, Akira Yoshimura, Makoto Miura, Kimitomo Yoshioka, Mitsuo Sakato, Iwao Ohtsuki, Yoshikazu Miwa, Fumi Takahashi-Yanaga, Toshiyuki Sasaguri
Publikováno v:
Journal of Pharmacological Sciences, Vol 97, Iss 1, Pp 53-60 (2005)
We investigated the effects of the agent SCH00013 on Ca2+-induced force generation in rabbit skinned cardiac muscle fibers and in vivo cardiac function in high-pacing-induced heart failure dogs. The Ca2+-induced force generation in skinned cardiac mu
Externí odkaz:
https://doaj.org/article/ef03b378013c4bc18d1eabe6fd8d5ecf
Autor:
Mitsuo Sakato, Akira Yoshimura, Masataka Hino, Masao Endoh, Hiromi Sugawara, Kimitomo Yoshioka
Publikováno v:
Arzneimittelforschung. 49:412-419
Influence of 4,5-dihydro-6-[1-[2-hydroxy-2-(4-cyanophenyl)ethyl]- 1,2,5,6,-tetrahydropyrido-4-yl]pyridazin-3(2H)-one (SCH00013) and vesnarinone (CAS 81840-15-5) on the arrhythmia experimentally induced by three different methods was investigated in d
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::23c147d26f8aae5048ad980b48f60c39
https://doi.org/10.1055/s-0031-1300436
https://doi.org/10.1055/s-0031-1300436
Autor:
Kimitomo Yoshioka, Masataka Hino, Akira Yoshimura, Akihiko Ogura, Hiromi Sugawara, Masao Endoh, Mitsuo Sakato
Publikováno v:
Arzneimittelforschung. 49:407-411
In order to clarify the mechanism of action of 4,5-dihydro-6-[1-[2-hydroxy-2-(4-cyanophenyl)ethyl]-1,2,5,6- tetrahydropyrido-4-yl]pyridazin-3(2H)-one (SCH00013), a novel cardiotonic agent with Ca++ sensitizing action, its effects on contractile force
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0106a8ab31fdc3cd00f8959dc5510f03
https://doi.org/10.1055/s-0031-1300435
https://doi.org/10.1055/s-0031-1300435
Publikováno v:
Journal of Toxicologic Pathology. 9:305-313
Protective effect of Sobuzoxane (MST-16) against cardiotoxicity of adriamycin (ADM) was inves-tigated in rabbits. ADM (1.0mg/kg) was administered intravenously twice a week for five weeks. MST-16(25mg/kg, p.o.) or ICRF- 187 (25mg/kg, i.p.) was admini
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dcbb381303e3cce739a12b63d7702a06
https://doi.org/10.1293/tox.9.305
https://doi.org/10.1293/tox.9.305
Autor:
Masataka Hino, Akihiko Ogura, Masao Endoh, Hiromi Sugawara, Kimitomo Yoshioka, Mitsuo Sakato, Akira Yoshimura
Publikováno v:
ChemInform. 30
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::aae80ba242938802ceff3bb6e0e4a277
https://doi.org/10.1002/chin.199932154
https://doi.org/10.1002/chin.199932154
Autor:
Shinichi Yaguchi, Katsuyasu Sakita, Yasuhiro Izumisawa, Masanobu Kato, Ichiro Koshimizu, Kimitomo Yoshioka, Tsutomu Nakagane, Seiichiro Kawashima, Makoto Sato, Mitsuo Sakato
Publikováno v:
Biological and Pharmaceutical Bulletin. 20:698-700
We examined in vitro cytotoxic activity of imidazolyl-1, 3, 5-triazine derivatives using human breast cancer cell lines (MCF-7, R-27, T-47D and ZR-75-1) and murine leukemia cell line (P388). The percentage of viable cells was determined by the 3-(4,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b9e3a958f49e0c6babcfaff4c15d5375
https://doi.org/10.1248/bpb.20.698
https://doi.org/10.1248/bpb.20.698
Autor:
Fumi Takahashi-Yanaga, Iwao Ohtsuki, Kimitomo Yoshioka, Naoto Tadano, Akira Yoshimura, Yoshikazu Miwa, Makoto Miura, Toshiyuki Sasaguri, Sachio Morimoto, Mitsuo Sakato
Publikováno v:
Journal of Pharmacological Sciences, Vol 97, Iss 1, Pp 53-60 (2005)
We investigated the effects of the agent SCH00013 on Ca2+-induced force generation in rabbit skinned cardiac muscle fibers and in vivo cardiac function in high-pacing-induced heart failure dogs. The Ca2+-induced force generation in skinned cardiac mu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffef6e5c599d9726a9a05cec5e668b3b
https://pubmed.ncbi.nlm.nih.gov/15644593
https://pubmed.ncbi.nlm.nih.gov/15644593
Publikováno v:
Journal of cardiovascular pharmacology. 42(3)
The authors examined the effects of long-term treatment with SCH00013, a novel cardiotonic agent with calcium-sensitizing action, on survival of hereditary cardiomyopathic BIO 14.6 hamsters. Sixty-nine male hamsters at 223 days of age were divided in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcb90b9bc1702129c906eefe71b9a606
https://pubmed.ncbi.nlm.nih.gov/12960681
https://pubmed.ncbi.nlm.nih.gov/12960681
Autor:
Masanobu Kato, Tetsuo Watanabe, Hiroya Sasahara, Seiichiro Kawashima, Masahiro Inaba, Shinichi Yaguchi, Toshiyuki Matsuno, Mitsuo Sakato, Kimitomo Yoshioka, Masayuki Takahashi
Publikováno v:
ChemInform. 32
Triamino-substituted 1,3,5-triazine and pyrimidine derivatives were synthesized and tested for antitumor activities using some human cancer cell lines and murine leukemia cell lines. All the compounds having benzimidazolyl and morpholino groups as su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8feb840ce8db91211597f953b2917b3b
https://doi.org/10.1002/chin.200113155
https://doi.org/10.1002/chin.200113155
Autor:
Akira Yoshimura, Hiromi Sugawara, Masao Endoh, Kimitomo Yoshioka, Masataka Hino, Mitsuo Sakato
Publikováno v:
Japanese Journal of Pharmacology. 79:180
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d5bf9b9c93fb28ae1dd969fd47b535a7
https://doi.org/10.1016/s0021-5198(19)34734-1
https://doi.org/10.1016/s0021-5198(19)34734-1