Zobrazeno 1 - 10
of 30
pro vyhledávání: '"Mitsuo Numata"'
Publikováno v:
Journal of Toxicology: Clinical Toxicology. 36:73-76
Poison centers are faced with the escalating costs of specialist staffing and increased investments in hardware and databases despite deficit funding. We developed an automated fax information system to access poison information from any fax machine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75252e9f6932661edf29c31cb35446df
https://doi.org/10.3109/15563659809162590
https://doi.org/10.3109/15563659809162590
Publikováno v:
ChemInform. 22
Guinesines A, B and C were synthesized starting from 1,3-bis(benzylthio)-2-propanone and N-methyl-2,2-diethoxypyrrolidine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::69c5cc045d5c67d36b99c024eb0be2ce
https://doi.org/10.1002/chin.199101337
https://doi.org/10.1002/chin.199101337
Autor:
Hiroyuki Mitsudera, Yoshiaki Kono, Yukiaki Manabe, Mitsuo Numata, Hideki Uneme, Toshiya Kamikado
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 56:2023-2033
A series of 1,2-dithiolanes, 1,2-dithianes and related compounds bearing a nitrogen-containing substituent were synthesized and their pesticidal activity was tested. A new general synthetic route to 1,2-dithiolanes was established from 1,3-diols. A v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::311de7ef3ad214e94100c8e6e7ce9fe4
https://doi.org/10.1271/bbb.56.2023
https://doi.org/10.1271/bbb.56.2023
Autor:
Mitsuo Numata, Yoshiaki Kono, Hiroyuki Mitsudera, Hideki Uneme, Yukiaki Manabe, Yamada Junji, Toshiya Kamikado
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 56:1293-1299
The structures of the insecticidal alkaloids, guinesines (4-hydroxy-3-(I-methyl-2-pyrrolidinyl)-1,2-ditbiolanes), were simplified in several ways while retaining the dithiolane ring. Most of the compounds synthesized showed activity against Chilo sup
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fe81175b16f3443e22a24352779d3021
https://doi.org/10.1271/bbb.56.1293
https://doi.org/10.1271/bbb.56.1293
Autor:
Hiroyuki Mitsudera, Yukiaki Manabe, Toshiya Kamikado, Yoshiaki Kono, Hideki Uneme, Mitsuo Numata, Yamada Junji
Publikováno v:
Bioscience, Biotechnology, and Biochemistry. 56:1623-1631
A variety of derivatives of 3- and 4-(dimethylaminomethyl)-1,2-dithiolanes were prepared as their biological equivalents in an analogous way to that for the nereistoxin derivatives. Most of them sh...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c32b6f73da5d0abf85d3d3cadc6b87b6
https://doi.org/10.1271/bbb.56.1623
https://doi.org/10.1271/bbb.56.1623
Publikováno v:
Journal of Heterocyclic Chemistry. 27:1361-1367
Guinesines A, B and C were synthesized starting from 1,3-bis(benzylthio)-2-propanone and N-methyl-2,2-diethoxypyrrolidine.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::806e25a2ae168ea91952a490a8eee785
https://doi.org/10.1002/jhet.5570270534
https://doi.org/10.1002/jhet.5570270534
Publikováno v:
The Journal of Antibiotics. 31:1252-1261
New cephalosporins modified in the acyl part of 7-(3'-oxobutyrylamino)cephalosporins (1), which have been described in the preceding paper, were synthesized by thiolation at the 2'- or the 4'-position, or by transforming the 3'-oxo group into a 3'-im
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5b837a09e96ac8767f113e5320c79d97
https://doi.org/10.7164/antibiotics.31.1252
https://doi.org/10.7164/antibiotics.31.1252
Autor:
Takatsuka Yashiki, Masayoshi Yamaoka, Mitsuo Numata, Nishimura Tatsuo, Naoru Hamaguchi, Shin-Ichiro Hirai, Yoshinobu Yoshimura, Kunio Takanohashi, Akio Miyake
Publikováno v:
The Journal of Antibiotics. 40:81-90
Orally active 1-(alkyl substituted cyclohexyloxycarbonyloxy)alkyl ester prodrugs (9b-h) of 7 beta-[2-(2-aminothiazol-4-yl)acetamido]-3- [[[1-(2-dimethylaminoethyl)-1H-tetrazol-5-yl]thio]-methyl]ceph+ ++-3- em-4-carboxylic acid (cefotiam, CTM) have be
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7519b8f01ed95d09ce37ba01ab2f0348
https://doi.org/10.7164/antibiotics.40.81
https://doi.org/10.7164/antibiotics.40.81
Autor:
Mitsuo Numata, Masayasu Kato, Norichika Matsumoto, Michiyuki Sendai, Mitsuru Shiraishi, Susumu Tsushima, Kenzo Naito
Publikováno v:
Chemical and Pharmaceutical Bulletin. 27:696-702
New compounds 3-acetoacetoxymethyl-7β-acylaminoceph-3-em-4-carboxylic acids (4) were synthesized from deacetylcephalosporin C (3a), after N-protection of the amino-adipoyl group followed by acetoacetylation of the 3'-hydroxyl with diketene and acyl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::239b2ed7e1c8ad1cdf0c755832c38073
https://doi.org/10.1248/cpb.27.696
https://doi.org/10.1248/cpb.27.696
Publikováno v:
Chemical and Pharmaceutical Bulletin. 21:112-117
The N-methyls in 2, 3-disubstituted N, N-dimethylpropylamines (I-VIII) have given two peaks with an equal intensity in an acid solution owing to the hindered internal rotation about the C-NMe2H+ bond. The energy barriers between two staggered forms h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9f7f2fbcd5de42938b9cd2cfa1b35b3a
https://doi.org/10.1248/cpb.21.112
https://doi.org/10.1248/cpb.21.112