Zobrazeno 1 - 10
of 325
pro vyhledávání: '"Mitsuo IKEBE"'
Autor:
Fan Yang, Alireza Labani-Motlagh, Jose Alejandro Bohorquez, Josimar Dornelas Moreira, Danish Ansari, Sahil Patel, Fabrizio Spagnolo, Jon Florence, Abhinav Vankayalapati, Tsuyoshi Sakai, Osamu Sato, Mitsuo Ikebe, Ramakrishna Vankayalapati, John J. Dennehy, Buka Samten, Guohua Yi
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract The continuing emergence of new strains of antibiotic-resistant bacteria has renewed interest in phage therapy; however, there has been limited progress in applying phage therapy to multi-drug resistant Mycobacterium tuberculosis (Mtb) infec
Externí odkaz:
https://doaj.org/article/1ac890637fe24a00b09370f2537cb206
Autor:
Xia Guo, Christudas Sunil, Oluwaseun Adeyanju, Andrew Parker, Steven Huang, Mitsuo Ikebe, Torry A. Tucker, Steven Idell, Guoqing Qian
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract Programmed death ligand-1 (PD-L1) is an immune checkpoint protein that has been linked with idiopathic pulmonary fibrosis (IPF) and fibroblast to myofibroblast transition (FMT). However, it remains largely unclear how PD-L1 mediates this pro
Externí odkaz:
https://doaj.org/article/667488909e5243a09413f200f51eb72e
Autor:
Ranisha Logan, Ann Jeffers, Wenyi Qin, Shuzi Owens, Prashant Chauhan, Satoshi Komatsu, Mitsuo Ikebe, Steven Idell, Torry A. Tucker
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Pleural fibrosis (PF) is a chronic and progressive lung disease which affects approximately 30,000 people per year in the United States. Injury and sustained inflammation of the pleural space can result in PF, restricting lung expansion and
Externí odkaz:
https://doaj.org/article/37c5767f7ee74cd3be9d3181c0fd820a
Publikováno v:
Life, Vol 12, Iss 6, p 843 (2022)
Fascin, a major actin cross-linking protein, is expressed in most vertebrate epithelial tissues. It organizes actin filaments into well-ordered bundles that are responsible for the extension of dynamic membrane protrusions, including microspikes, fil
Externí odkaz:
https://doaj.org/article/c8ed8aa5865248e7a1882ecd04787add
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Filopodia protrude from the leading edge of cells and play important roles in cell motility. Here we report the mechanism of myosin X (encoded by Myo10)-induced multi-cycle filopodia extension. We found that actin, Arp2/3, vinculin and integ
Externí odkaz:
https://doaj.org/article/1d9aaba67a494c1db325ab4a0b2f6467
Autor:
Hirotoshi Kamata, Yoshikazu Tsukasaki, Tsuyoshi Sakai, Reiko Ikebe, Julia Wang, Ann Jeffers, Jake Boren, Shuzi Owens, Takahiro Suzuki, Masaaki Higashihara, Steven Idell, Torry A. Tucker, Mitsuo Ikebe
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Abstract Fibrosis involves the production of extracellular matrix proteins in tissues and is often preceded by injury or trauma. In pleural fibrosis excess collagen deposition results in pleural thickening, increased stiffness and impaired lung funct
Externí odkaz:
https://doaj.org/article/9c07477bd0e4450b94bd1147a0932edd
Autor:
Satyanarayana Swamy Cheekatla, Deepak Tripathi, Sambasivan Venkatasubramanian, Pavan Kumar Nathella, Padmaja Paidipally, Munenori Ishibashi, Elwyn Welch, Amy R Tvinnereim, Mitsuo Ikebe, Vijaya Lakshmi Valluri, Subash Babu, Hardy Kornfeld, Ramakrishna Vankayalapati
Publikováno v:
PLoS Pathogens, Vol 12, Iss 10, p e1005972 (2016)
In this study, we developed a mouse model of type 2 diabetes mellitus (T2DM) using streptozotocin and nicotinamide and identified factors that increase susceptibility of T2DM mice to infection by Mycobacterium tuberculosis (Mtb). All Mtb-infected T2D
Externí odkaz:
https://doaj.org/article/1632fad0303f48a0a4efb8a496c08bf3
Autor:
Tae-Jun Kwon, Se-Kyung Oh, Hong-Joon Park, Osamu Sato, Hanka Venselaar, Soo Young Choi, SungHee Kim, Kyu-Yup Lee, Jinwoong Bok, Sang-Heun Lee, Gert Vriend, Mitsuo Ikebe, Un-Kyung Kim, Jae Young Choi
Publikováno v:
Open Biology, Vol 4, Iss 7 (2014)
Mutations in five unconventional myosin genes have been associated with genetic hearing loss (HL). These genes encode the motor proteins myosin IA, IIIA, VI, VIIA and XVA. To date, most mutations in myosin genes have been found in the Caucasian popul
Externí odkaz:
https://doaj.org/article/145dba04990f4e779e878c8183f3065a
Autor:
Cheng-Hai Zhang, Lawrence M. Lifshitz, Karl F. Uy, Mitsuo Ikebe, Kevin E. Fogarty, Ronghua ZhuGe
Publikováno v:
PLoS Biology, Vol 11, Iss 3 (2013)
Externí odkaz:
https://doaj.org/article/b7d89b1976cb4c398032d34f1423dd16
Autor:
Cheng-Hai Zhang, Lawrence M Lifshitz, Karl F Uy, Mitsuo Ikebe, Kevin E Fogarty, Ronghua ZhuGe
Publikováno v:
PLoS Biology, Vol 11, Iss 3, p e1001501 (2013)
Bronchodilators are a standard medicine for treating airway obstructive diseases, and β2 adrenergic receptor agonists have been the most commonly used bronchodilators since their discovery. Strikingly, activation of G-protein-coupled bitter taste re
Externí odkaz:
https://doaj.org/article/262ea3197d5347849e4fdd416550c750