Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Mitsuo Hayakawa"'
Publikováno v:
Hybridoma. 28:431-434
An important periodontal pathogen, Porphyromans gingivalis strains are classified into six genotypes (types I-V and Ib), based on the genotype of the fimbriae A (fimA). Among the genotypes, fimA type II strains are thought to be most strongly related
Publikováno v:
International Journal of Oral-Medical Sciences. 7:107-112
Porphyromonas gingivalis, a gram-negative anaerobic bacterium, is considered to be one of the major etiologic agents of adult periodontitis. We previously succeeded in the gene cloning of a 200-kDa antigenic protein (200-kDa-Ag) from P. gingivalis 38
Autor:
Isao Ishida, Yoshimitsu Abiko, Tetsuo Kobayashi, Kumiko Nakazawa, Tomoyuki Tahara, Hiromasa Yoshie, Yasuko Shibata, Mitsuo Hayakawa, Ayano Takauchi
Publikováno v:
Journal of Periodontology. 76:680-685
As a safe immunotherapeutic approach, human monoclonal antibody (hMAb) may be effective in clearing periodontopathic bacteria. The trans-chromosomic (TC) technology has recently been applied to construction of the TC mouse, which enables us to incorp
Autor:
Mitsuo Hayakawa, Yoshimitsu Abiko, Kazuo Fukushima, Teruaki Shiroza, Noriko Shinozaki-Kuwahara
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1722:189-199
We have constructed a Streptococcus anginosus transformant expressing the gtfI gene from Streptococcus sobrinus, using a previously developed integration-mediated transformation system to introduce foreign genes onto the oral streptococcal chromosome
Autor:
Mitsuo Hayakawa, Teruaki Shiroza, Hiroyoshi Tagawa, Yoshimitsu Abiko, Kazuo Fukushima, M Sheng-Yang Lee, Yasuko Shibata
Publikováno v:
Hybridoma and Hybridomics. 23:305-310
Streptococcus mutans has been considered the principal etiologic agent of dental caries in humans. The glucosyltransferase-I (GTF-I), which synthesized adhesive water-insoluble glucans from sucrose, has been demonstrated to be an important cariogenic
Autor:
Yoshimitsu Abiko, Masafumi Yamamoto, Mitsuo Hayakawa, Satomi Maeba, Shigeo Otake, Jun Namikoshi
Publikováno v:
International Journal of Oral-Medical Sciences. 3:67-74
Porphyromonus gingivalis is a major pathogen of chronic periodontitis. An outer membrane protein with a molecular mass of 40-kDa (40k-OMP) is a highly immunogenic surface protein produced by P. gingivalis. In this study, to develop an effective vacci
Autor:
Tomomi Hashizume, Shigezo Udaka, Noriko Shinozaki-Kuwahara, Kazuo Fukushima, Teruaki Shiroza, Mitsuo Hayakawa, Yoshimitsu Abiko, Yasuko Shibata
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1626:57-64
Periodontitis and dental caries are common oral diseases, in these days, and the passive immunization is one of the most effective approaches for prevention. For this purpose, we have constructed mouse and human monoclonal antibodies to inhibit the P
Autor:
Mitsuo Hayakawa, Yoshimitsu Abiko, Masafumi Yamamoto, Satomi Maeba, Shigeo Otake, Jun Namikoshi
Publikováno v:
International Journal of Oral-Medical Sciences. 1:90-96
It is well established that Porphyromonas gingivalis is one of the major pathogens of adult periodontitis. P. gingivalis produces an outer membrane protein with a molecular mass of 40-kDa (40k-OMP). In the present study, in order to assess the potent
Publikováno v:
SEIBUTSU BUTSURI KAGAKU. 47:151-154
We constructed a large-scale preparative gel electrophoresis device equipped with a 10-cm in diameter gel support column and used it with an electroosmotic medium pump system (EOMPS). Operation of the constructed apparatus was examined and resolution
Autor:
Hidenobu Senpuku, Nobuhiro Hanada, Mitsuo Hayakawa, Yoshimitsu Abiko, Teruaki Shiroza, Yoshiaki Nomura, Kazuo Fukushima, Hidehiko Mukasa
Publikováno v:
Biochimica et Biophysica Acta (BBA) - General Subjects. 1570:75-79
Streptococcus sobrinus has four gtf genes, gtfI, gtfS, gtfT, and gtfU, on the chromosome. These genes correspond respectively to the enzymes GTF-I, GTF-S1, GTF-S2, and GTF-S3. An Escherichia coli MD66 clone that contained the S. sobrinus gtfU gene wa