Zobrazeno 1 - 10
of 197
pro vyhledávání: '"Mitsuo Hashimoto"'
Autor:
Akihiko Ito, Mitsuo Hashimoto, Jun Tanihata, Sachi Matsubayashi, Ryoko Sasaki, Shota Fujimoto, Hironori Kawamoto, Yusuke Hosaka, Akihiro Ichikawa, Tsukasa Kadota, Yu Fujita, Daisuke Takekoshi, Sabro Ito, Shunsuke Minagawa, Takanori Numata, Hiromichi Hara, Tatsuki Matsuoka, Jun Udaka, Jun Araya, Mitsuru Saito, Kazuyoshi Kuwano
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 13, Iss 3, Pp 1864-1882 (2022)
Abstract Background Sarcopenia is characterized by the loss of skeletal muscle mass and strength and is associated with poor prognosis in patients with chronic obstructive pulmonary disease (COPD). Cigarette smoke (CS) exposure, a major cause for COP
Externí odkaz:
https://doaj.org/article/ad895a5d387e4cd6855dea08a616154a
Autor:
Takanori Numata, Hanae Miyagawa, Saiko Nishioka, Keitaro Okuda, Hirofumi Utsumi, Mitsuo Hashimoto, Shunsuke Minagawa, Takeo Ishikawa, Hiromichi Hara, Jun Araya, Kazuyoshi Kuwano
Publikováno v:
BMC Pulmonary Medicine, Vol 20, Iss 1, Pp 1-10 (2020)
Abstract Background Benralizumab, an anti-interleukin-5 (IL-5) receptor α monoclonal antibody, significantly reduces the number of annual exacerbations and oral corticosteroid (OCS) maintenance doses for patients with severe eosinophilic asthma (SEA
Externí odkaz:
https://doaj.org/article/dad4c27f3770442ba57c71cc9b082581
Autor:
Takanori Numata, Katsutoshi Nakayama, Hirofumi Utsumi, Kenji Kobayashi, Haruhiko Yanagisawa, Mitsuo Hashimoto, Shunsuke Minagawa, Takeo Ishikawa, Hiromichi Hara, Jun Araya, Kazuyoshi Kuwano
Publikováno v:
BMC Pulmonary Medicine, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background Several major randomized control studies have demonstrated that mepolizumab, an anti-IL-5 monoclonal antibody, is effective for patients with severe eosinophilic asthma who show exacerbation or require systemic corticosteroid main
Externí odkaz:
https://doaj.org/article/15a0fc23ace545159587a6dcd813756e
Autor:
Takanori Numata, Hanae Miyagawa, Hironori Kawamoto, Masahiro Yoshida, Hirofumi Utsumi, Mitsuo Hashimoto, Shunsuke Minagawa, Hiromichi Hara, Jun Araya, Kazuyoshi Kuwano
Publikováno v:
Cogent Medicine, Vol 7, Iss 1 (2020)
Abstract Mepolizumab significantly reduces the number of annual exacerbations (AEs) and the maintenance dose of systemic corticosteroids (CSs) in patients with severe eosinophilic asthma (SEA). However, there are few studies based on real life with a
Externí odkaz:
https://doaj.org/article/f8e3528a885541f196ce6ed3cb3639bd
Autor:
Takanori Numata, Katsutoshi Nakayama, Satoko Fujii, Yoko Yumino, Nayuta Saito, Masahiro Yoshida, Yusuke Kurita, Kenji Kobayashi, Saburo Ito, Hirofumi Utsumi, Haruhiko Yanagisawa, Mitsuo Hashimoto, Hiroshi Wakui, Shunsuke Minagawa, Takeo Ishikawa, Hiromichi Hara, Jun Araya, Yumi Kaneko, Kazuyoshi Kuwano
Publikováno v:
BMC Pulmonary Medicine, Vol 18, Iss 1, Pp 1-8 (2018)
Abstract Background Postoperative pulmonary complications (PPC) in patients with pulmonary diseases remain to be resolved clinical issue. However, most evidence regarding PPC has been established more than 10 years ago. Therefore, it is necessary to
Externí odkaz:
https://doaj.org/article/d3b90ddb33734d108fc053a57367d64e
Autor:
Yusuke Kurita, Jun Araya, Shunsuke Minagawa, Hiromichi Hara, Akihiro Ichikawa, Nayuta Saito, Tsukasa Kadota, Kazuya Tsubouchi, Nahoko Sato, Masahiro Yoshida, Kenji Kobayashi, Saburo Ito, Yu Fujita, Hirofumi Utsumi, Haruhiko Yanagisawa, Mitsuo Hashimoto, Hiroshi Wakui, Yutaka Yoshii, Takeo Ishikawa, Takanori Numata, Yumi Kaneko, Hisatoshi Asano, Makoto Yamashita, Makoto Odaka, Toshiaki Morikawa, Katsutoshi Nakayama, Kazuyoshi Kuwano
Publikováno v:
Respiratory Research, Vol 18, Iss 1, Pp 1-14 (2017)
Abstract Background Pirfenidone (PFD) is an anti-fibrotic agent used to treat idiopathic pulmonary fibrosis (IPF), but its precise mechanism of action remains elusive. Accumulation of profibrotic myofibroblasts is a crucial process for fibrotic remod
Externí odkaz:
https://doaj.org/article/1146926490a44a5c8c9022cb1d7ba748
Autor:
Luiz Augusto Tolomei, Mitsuo Hashimoto, Caroline Ferreira da Silva Mazeto, Augusto Tomimatsu Shimauti, Maria Rosa Bet de Moraes Silva, Carlos Roberto Padovani, Silvana Artioli Schellini
Publikováno v:
Revista Brasileira de Oftalmologia, Vol 75, Iss 3, Pp 209-213 (2016)
RESUMO Objetivo: Avaliar a utilidade do tonômetro de ar (TA) em estudos populacionais em indivíduos suspeitos de hipertensão ocular, comparando os valores com os fornecidos pelo tonômetro de aplanação de Goldmann (TG). Métodos: Estudo transver
Externí odkaz:
https://doaj.org/article/6a05e2d06fdb451f8f93666f712d1272
Autor:
Eduardo Andreghetti, Mitsuo Hashimoto, Maria Aparecida Custódio Domingues, Vitor Andrigheti Coronado Antunes, Paulo de Souza Segundo, Maria Rosa Bet de Moraes Silva
Publikováno v:
Acta Cirúrgica Brasileira, Vol 28, Iss 9, Pp 632-640 (2013)
PURPOSE: To investigate and compare the biocompatibility of two types of Ferrara intracorneal ring segment: with and without chondroitin sulfate coating by clinical and histopathological evaluation. METHODS: A randomized experimental study was carrie
Externí odkaz:
https://doaj.org/article/d88b1a88b92b4e95a8041f55351d7a37
Publikováno v:
Journal of Advanced Mechanical Design, Systems, and Manufacturing, Vol 8, Iss 3, Pp JAMDSM0039-JAMDSM0039 (2014)
Gear is one of the most important and commonly used components in machine system. Some gear failure may lead to fatal damage of the entire system, or even huge losses in industrial production. Early detection of gear damage is crucial to prevent the
Externí odkaz:
https://doaj.org/article/58ad0a61c2a84e2a9eaf380f599bea39
Publikováno v:
Journal of Advanced Mechanical Design, Systems, and Manufacturing, Vol 8, Iss 3, Pp JAMDSM0021-JAMDSM0021 (2014)
The operation status of gear device can directly affect the working conditions of the whole machine system. Thus, it is crucial to detect the gear damage as early as possible to prevent the system from malfunction. This paper proposes an intelligent
Externí odkaz:
https://doaj.org/article/1b028ddc50904f78b0226d427a696074