Zobrazeno 1 - 10
of 62
pro vyhledávání: '"Mitsuo, Tashiro"'
Autor:
Hayato Nakamura, Yoko Nomiyama, Makoto Otsuki, Hiroshi Asaumi, T Miyamoto, Shiro Watanabe, M. Kaku, Mitsuo Tashiro
Publikováno v:
Gut. 57:788-798
Background: Smad6 is implicated in the inhibition of bone morphogenetic protein signalling. However, the function of Smad6 in the pancreas remains obscure. Methods: To elucidate the unknown function of Smad6, we developed transgenic mice selectively
Autor:
Hayato Nakamura, Tamao Miyamoto, Yoshikuni Nagashio, Makoto Otsuki, Hiroshi Asaumi, Yoko Nomiyama, Mitsuo Tashiro, Taizo Yamaguchi, Shiro Watanabe
Publikováno v:
Pancreas. 35:e23-e29
Objectives To elucidate the role of transforming growth factor (TGF) beta1 and extracellular matrix (ECM) after acute necrotizing pancreatitis, we studied the regulation of TGF-beta1 and ECM after induction of pancreatitis. Methods We examined the se
Publikováno v:
Journal of Robotics and Mechatronics. 19:331-338
We developed a catheter drive with two rotors that pinch an aspiration catheter between them and incline along the perpendicular of the catheter axis at mutually opposite angles. Rotors are driven with the same torque in opposite directions to minimi
Autor:
Mitsuo Tashiro, Makoto Otsuki, Masahiro Yamasaki, Keiichiro Kume, Kikuo Kanda, Akinari Tabaru, Ichiro Yoshikawa, Masashi Taguchi
Publikováno v:
Diseases of the Colon & Rectum. 49:1393-1398
PURPOSE: Premedication with glucagon or hyoscyamine is reported to be effective in reducing colonic spasm. However, these drugs can be associated with unfavorable events. This prospective study was designed to compare the effects of premedication wit
Autor:
Yoshikuni Nagashio, Yasuyuki Kihara, Taizo Yamaguchi, Masashi Taguchi, Mitsuo Tashiro, Makoto Otsuki, Hayato Nakamura
Publikováno v:
Pancreas. 31:365-372
Background and aims The imbalance between synthesis and degradation of extracellular matrix (ECM) proteins is a characteristic feature in chronic pancreatitis. We evaluated the relationship between type IV collagen structure in the basement membrane
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 286:G784-G790
CCK acts on pancreatic acinar cells to increase intracellular Ca2+leading to secretion of digestive enzymes and, in the long term, pancreatic growth. Calcineurin (CN) is a serine/threonine-specific protein phosphatase activated by Ca2+and calmodulin
Publikováno v:
Internal Medicine. 55:2513-2514
Publikováno v:
Pancreas. 26:160-165
Introduction: Survivin is one of the inhibitors of the apoptosis family and has dual effects: antiapoptotic effect and regulation of the cell cycle. Aim: To show involvement of survivin in acute pancreatitis. Methodology: Acute necrohemorrhagic pancr
Autor:
John A. Williams, Mitsuo Tashiro, M. Julia Bragado, M. Dolors Sans, Andrzej Dabrowski, Claus Schäfer
Publikováno v:
Pharmacology & Toxicology. 91:297-303
Cholecystokinin (CCK) acting through its G protein-coupled receptor is now known to activate a variety of intracellular signaling mechanisms and thereby regulate a complex array of cellular functions in pancreatic acinar cells. The best studied mecha
Autor:
Toshiharu Akiyama, Mitsuo Tashiro, Yoshinori Okabayashi, Issei Imoto, Yoshihide Hirohata, Makoto Otsuki, Masatoshi Fujii, Yoshikuni Nagashio
Publikováno v:
American Journal of Physiology-Gastrointestinal and Liver Physiology. 282:G249-G256
Considered to be an etiologic factor of acute pancreatitis, hypersecretion of pancreatic juice and digestive enzymes is often associated with hyperbilirubinemia. We explored the intracellular mechanisms through which bilirubin affects pancreatic exoc