Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mitsunobu Nakatsuka"'
Publikováno v:
International Journal of Immunopharmacology. 13:11-19
Antimetastatic effects of the monosaccharic lipid A-subunit analogue GLA-60 against B16-F10 melanomas were investigated. Intravenous injection of 10 micrograms GLA-60 one day or two days before transplantation of 10(5) melanoma cells resulted in a si
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::19d63684a430e5ecbe89f23bacb66087
https://doi.org/10.1016/0192-0561(91)90020-8
https://doi.org/10.1016/0192-0561(91)90020-8
Autor:
Mitsunobu Nakatsuka, Chiaki Nishimura, Akira Hasegawa, Yoshio Kumazawa, S. Ikeda, Makoto Kiso, J. Yuzuru Homma, Motohiro Matsuura
Publikováno v:
International journal of immunopharmacology. 12(6)
The C1 position of lipid A-subunit analogue GLA-27, 4-O- phosphono - D - gluxosamine carrying N -3-tetradecanoyloxytetradecanoyl(C 14 - O -(C 14 )) and 3- O -tetradecanoyl (C 14) groups, was S -acetylated, thiolated or phosphorylated. Enhancement of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::edf75be1a8d025b6ff0c7ca13bf4d6c3
https://pubmed.ncbi.nlm.nih.gov/1703131
https://pubmed.ncbi.nlm.nih.gov/1703131
Autor:
Mitsunobu Nakatsuka
Publikováno v:
Development, Growth and Differentiation. 27:653-661
The intracellular hatching enzyme was confirmed to be particulate-bound in the sea urchin, Hemicentrotus pulcherrimus. The enzyme was solubilized most effectively by sonication in buffer containing 12.5 mM CaCl2, and 0.5 M KCl. The intracellular hatc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ee5e4afaca5638c669974209984f77a4
https://doi.org/10.1111/j.1440-169x.1985.00653.x
https://doi.org/10.1111/j.1440-169x.1985.00653.x
Autor:
Mitsunobu Nakatsuka
Publikováno v:
Development, Growth and Differentiation. 21:245-253
The effect of salts on hatching enzyme and protease from the embryo of the sea urchin, Hemicentrotus pulcherrimus, was investigated. The culture medium containing hatching enzyme secreted from the hatched blastula was dialyzed against Tris-HCl (pH 8.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::baff6ad023b6b06502166f880359afbc
https://doi.org/10.1111/j.1440-169x.1979.00245.x
https://doi.org/10.1111/j.1440-169x.1979.00245.x
Publikováno v:
International Journal of Immunopharmacology. 11:349-358
Enhancement of nonspecific resistance against Pseudomonas aeruginosa infection and regression of growth of Meth A fibrosarcoma by chemically synthesized lipid A-subunit analogs, 4-O- phosphono - D - glucosamine derivatives carrying 3-O- and N-linked
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::934c85fc11d4c06f6886a986f5c8dd06
https://doi.org/10.1016/0192-0561(89)90080-5
https://doi.org/10.1016/0192-0561(89)90080-5
Autor:
Mitsunobu Nakatsuka
Publikováno v:
Development, Growth and Differentiation. 23:371-380
The time course of change in hatching enzyme activity during development of embryos of the sea urchin Hemicentrotus pulcherrimus was observed. The enzyme was present in the particulate fraction in embryos until the time of hatching and was maximal at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f7e9c53c3912b2c6e004e3d4934b417c
https://doi.org/10.1111/j.1440-169x.1981.00371.x
https://doi.org/10.1111/j.1440-169x.1981.00371.x
Autor:
Chiaki Nishimura, Mitsunobu Nakatsuka, Makoto Kiso, Akira Hasegawa, J. Yuzuru Homma, S. Ikeda
Publikováno v:
Antiviral research. 9(1-2)
Biological and antiviral activities of chemically synthesized lipid A-subunit analogues, GLA-27 and GLA-60, were investigated with respect to defense mechanisms such as macrophage and natural killer (NK) cell activation and interferon (IFN)-indluding
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::45419c03db2e4ef1a47ffe012f90dcac
https://pubmed.ncbi.nlm.nih.gov/3389769
https://pubmed.ncbi.nlm.nih.gov/3389769
Autor:
Chiaki Nishimura, Akira Hasegawa, Yoshio Kumazawa, S. Ikeda, Makoto Kiso, Mitsunobu Nakatsuka, J. Yuzuru Homma
Publikováno v:
Antiviral research. 10(4-5)
Protection against vaccinia virus infection and induction of interferon (IFN) were investigated in Propionibacterium acnes-primed mice following treatment with chemically synthesized lipid A-subunit derivatives. The antiviral activity was based on th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::433969bf194b69d7e225cd47e2125cc6
https://pubmed.ncbi.nlm.nih.gov/2465734
https://pubmed.ncbi.nlm.nih.gov/2465734
Autor:
J. Yuzuru Homma, S. Ikeda, Yoshio Kumazawa, Mitsunobu Nakatsuka, Chiaki Nishimura, Makoto Kiso, Akira Hasegawa, Akihiro Yamamoto, Hiroaki Takimoto
Publikováno v:
European journal of immunology. 17(5)
Tumor necrosis factor (TNF)-inducing, mitogenic, polyclonal B cell activation (PBA), macrophage activation and antiviral activities of chemically synthesized lipid A-subunit analogues, GLA-27 and GLA-40, were investigated. The structure of GLA-27 com
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::db4d5ab90f43b51bbea1c92275367947
https://pubmed.ncbi.nlm.nih.gov/3495442
https://pubmed.ncbi.nlm.nih.gov/3495442
Autor:
Makoto Kiso, Kazutoshi Sai, Chiaki Nishimura, Mitsunobu Nakatsuka, Akira Hasegawa, Ikeda Satoru, Akihiro Yamamoto, Homma^ J. Yuzuru, Yoshio Kumazawa
Publikováno v:
International journal of immunopharmacology. 10(4)
A lipid A-subunit analogue GLA-27, a 4-O-phosphono-D-glucosamine derivative carrying 3-O-tetradecanoyl and N-3-tetradecanoyloxytetradecanoyl groups, exhibited significant biological activities but no detectable pyrogenicity or local Shwarzman activit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::90c870cde9a8641ee4c5cc2544bd16f6
https://pubmed.ncbi.nlm.nih.gov/2459075
https://pubmed.ncbi.nlm.nih.gov/2459075