Zobrazeno 1 - 10
of 304
pro vyhledávání: '"Mitsunobu, Doi"'
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 80, Iss 9, Pp 942-946 (2024)
The cyclic peptide cyclo(Val-Leu-Leu-D-Phe-Pro)2 (peptide 1) was specifically designed for structural chemistry investigations, drawing inspiration from Gramicidin S (GS). Previous studies have shown that Pro residues within 1 adopt a down-puckering
Externí odkaz:
https://doaj.org/article/1b8653b7c5694aa6a8c36fe9fb50f242
Autor:
Akihiro Iyoshi, Atsushi Ueda, Tomohiro Umeno, Takuma Kato, Kazuhiro Hirayama, Mitsunobu Doi, Masakazu Tanaka
Publikováno v:
Molecules, Vol 29, Iss 18, p 4340 (2024)
Conformational freedom-restricted peptides, such as stapled peptides, play a crucial role in the advancement of functional peptide development. We synthesized stapled octapeptides using α-carbocyclic α,α-disubstituted α-amino acids, particularly
Externí odkaz:
https://doaj.org/article/fcd2f8df06b04149ab8e38e546cc95ec
Publikováno v:
ACS Omega, Vol 8, Iss 46, Pp 44106-44111 (2023)
Externí odkaz:
https://doaj.org/article/fd47183cf162473e9dd4c96b3128edb7
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 75, Iss 5, Pp 585-588 (2019)
In the title homotripeptide {Boc-[Asp(OMe)]3-OPac}, C28H37N3O13, all peptide bonds adopt an s-trans conformation with respect to the N—H and C=O groups. In the crystal, N—H...O hydrogen bonds result in an infinite parallel β-sheet structure runn
Externí odkaz:
https://doaj.org/article/88c04977732945c98f5d6f1477b7f188
Publikováno v:
RSC Advances. 13:2458-2466
The thermodynamic parameters through NMR-based quantitation provided evidence for the CH⋯π interaction in phenyl group-incorporated ascidiacyclamide. Stabilization of the square form by CH⋯π interaction resulted in increased cytotoxicity.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::10c297d5141639a91189bbd21afa83d7
https://doi.org/10.1039/d2ra07063d
https://doi.org/10.1039/d2ra07063d
Publikováno v:
ACS Omega, Vol 3, Iss 6, Pp 6395-6399 (2018)
Externí odkaz:
https://doaj.org/article/30981a11caf24fc9b0d9f5e52a9a06f5
Publikováno v:
Chemistry Letters. 52:246-248
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::714f3ba8b9b9cbd3bead70a3ccadf8c3
https://doi.org/10.1246/cl.230063
https://doi.org/10.1246/cl.230063
Publikováno v:
Chemical and Pharmaceutical Bulletin. 70:812-817
Amphipathic cell-penetrating peptides based on the pep-1 sequence were synthesized by replacing the three hydrophilic glutamic acid residues with disubstituted, non-proteinogenic, hydrophobic amino acids. These substitutions facilitated maintenance o
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c14b52007ae75e701812b89dd8f15d9
https://doi.org/10.1248/cpb.c22-00472
https://doi.org/10.1248/cpb.c22-00472
Autor:
Takuma Kato, Mitsunobu Doi
Publikováno v:
Acta Crystallographica Section E: Crystallographic Communications, Vol 73, Iss 12, Pp 1974-1976 (2017)
The crystal structure of the title compound, C14H15BF2N2O2, which comprises a boron–dipyrromethene (BODIPY) backbone and a propionic acid group, has been determined at 100 K. The BODIPY fused-ring system is nearly planar, with a maximum deviation f
Externí odkaz:
https://doaj.org/article/a25ab0833a3440d388cffadde4e49ad5
Publikováno v:
CHIMIA, Vol 72, Iss 12 (2018)
The cyclopentene-based ?,?-disubstituted ?-amino acid Ac5c= and its homopeptides, up to nonapeptides, were synthesized. The side-chain cyclopentene was expected to become symmetric, the C?-carbon to be puckered, and other C?, C?', C?, C?'-carbons to
Externí odkaz:
https://doaj.org/article/2c5bdc05c6704d0fa028babb6acbb1c3