Výsledky vyhledávání - "Mitsuno Shindo"

Fatty acyl-gramicidin S derivatives with both high antibiotic activity and low hemolytic activity

Autor: Kenta Fujinuma, Mitsuno Shindo, Makoto Tamaki, Yoshiki Uchida, Takuji Harada, Masahiro Kimura, Kazumasa Takanashi

Publikováno v: Bioorganic & Medicinal Chemistry Letters. 22:106-109

In the present study, novel eight GS derivatives having the octanoyl-(Lys)n- moieties, cyclo{-Val-Orn-Leu- d -Phe-Pro(4β-NH-X)-Val-Orn-Leu- d -Phe-Pro-} {X = −H (1), and -(Lys)n-CO(CH2)6CH3 n = 0 (2), 1 (3), 2 (4), and 3 (5)} and cyclo{-Val-Orn-Le

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::873eb0a270f4364f5002b0b0d53da757
https://doi.org/10.1016/j.bmcl.2011.11.062

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Synthesis of Novel Fatty-Acyl Gratisin Derivatives

Autor: Kenta Fujinuma, Takuji Harada, Yoshiki Uchida, Makoto Tamaki, Masahiro Kimura, Kazumasa Takanashi, Mitsuno Shindo

Publikováno v: Chemical and Pharmaceutical Bulletin. 60:743-746

To find candidates with high antimicrobial and low hemolytic activities, many gratisin (GR) analogues have been designed and synthesized. In the present account, we synthesized novel derivatives of GR having both the polycationic and fatty acyl group

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25e4912a266d57c88dfbe243b56ad713
https://doi.org/10.1248/cpb.60.743

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Polycationic Gramicidin S Analogues with Both High Antibiotic Activity and Very Low Hemolytic Activity

Autor: Masahiro Kimura, Kazumasa Takanashi, Yoshiki Uchida, Makoto Tamaki, Kenta Fujinuma, Takuji Harada, Mitsuno Shindo

Publikováno v: Chemical and Pharmaceutical Bulletin. 60:1134-1138

The substitution of each constituent amino acid residue of gramicidin S (GS), cyclo(-Val(1,1')-Orn(2,2')-Leu(3,3')-D-Phe(4,4')-Pro(5,5')-)(2) with Lys residue indicated that each side chain structure of the constituent amino acid residues affect larg

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b90e8be30b042b3ce63e4e0446496d75
https://doi.org/10.1248/cpb.c12-00290

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Novel Cycloundecapeptides Related to Gramicidin S with Both High Antibiotic Activity and Low Hemolytic Activity

Autor: Takuji Harada, Yoshiki Uchida, Kenta Fujinuma, Mitsuno Shindo, Makoto Tamaki, Masahiro Kimura, Kazumasa Takanashi

Publikováno v: Chemical and Pharmaceutical Bulletin. 59:1481-1484

To find candidates with high antimicrobial and low hemolytic activities, many gramicidin S (GS) analogs of various ring sizes have been designed and synthesized. However, syntheses of antimicrobially active analogues of GS having a disordered symmetr

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::70cc2cdb3fef48ff44d0f43b12ee2fe6
https://doi.org/10.1248/cpb.59.1481

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Antibacterial Activity of Short Peptides Based on Pleurocidin and Their Interaction with Phospholipid Membranes

Autor: Nobuaki Tsuda, Setsuko Ando, Haruhiko Aoyagi, Yoshiki Uchida, Tomomitsu Hatakeyama, Yukari Koba, Mitsuno Shindo

Publikováno v: Bulletin of the Chemical Society of Japan. 81:1299-1303

We have studied antibacterial activities of model peptides based on Pleurocidin (Ple). In this study, to investigate the effect of the C-terminal portion of these model peptides on antibacterial activity, we synthesized several short peptides which a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::1f8aa90187f8f3d1be4984407adee408
https://doi.org/10.1246/bcsj.81.1299

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Study of food coal-tar dyes (X) : Effects of chelate compounds on the discoloration of dye hues caused by metal ions (2)

Autor: Mitsuno, SHINDO, Yoshiki, UCHIDA

Publikováno v: 大阪樟蔭女子大学学芸学部論集. 45:95-111

金属イオンによる食用タール色素の変色、退色に対するEDTA2Na、PDTA、EDTAAM、NTA3NaおよびHEDTA の添加効果を検討した。銅イオン添加で影響を受けたアゾ系色素、インジゴイド系色素におい�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=jairo_______::9a90ec30ba3d41d26b9a281b88815459
http://id.nii.ac.jp/1072/00002099/

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Study of Food Coal-Tar Dyes (VI) : Effects of Phosphates on the Discoloration of Dye Hues Caused by Metal Ions (3)

Autor: Mitsuno, SHINDO, Yoshiki, UCHIDA

Publikováno v: 大阪樟蔭女子大学学芸学部論集. 41:99-115

本報では、銅、鉄、すず、アルミニウムイオンによる食用タール色素の変色・退色に対するNH_4H_2PO_4、(NH_4)_2HPO_4、(NH_4)_3PO_4、CaHPO_4、Ca(H_2PO_4)_2、Ca_3(PO_4)_2の添加効果を検討した。銅イオ�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=jairo_______::935aef41211eee9e136ba3ad161f233c
http://id.nii.ac.jp/1072/00001894/

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Study of Food Coal-Tar Dyes (V) : Effects of Phosphates on the Discoloration of Dye Hues Caused by Metal Ions (2)

Autor: Mitsuno, SHINDO, Yoshiki, UCHIDA

Publikováno v: 大阪樟蔭女子大学学芸学部論集. 40:69-85

本報では、銅、鉄、すず、アルミニウムイオンによる食用タールの変色・退色に対するりん酸塩(ピロりん酸カリウム、ピロりん酸ナトリウム、ピロりん酸二水素二ナトリウム、メタりん

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=jairo_______::284e0796864f4b9f3ccb8c0ea018f075
http://id.nii.ac.jp/1072/00001816/

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Study of Food Coal-Tar Dyes (IV) : Effects of Phosphates on the Discoloration of Dye Hues Caused by Metal Ions (1)

Autor: Mitsuno, SHINDO, Yoshiki, UCHIDA

Publikováno v: 大阪樟蔭女子大学学芸学部論集. 39:79-92

本報では,銅,鉄,すず,アルミニウムイオンによる食用タール色素の変色・退色に対するりん酸のナトリウム塩(りん酸一ナトリウム,りん酸二ナトリウム,りん酸三ナトリウム)およびカリウ�

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=jairo_______::673a4b53263674ff69210cfde680862a
http://id.nii.ac.jp/1072/00001731/

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Salusin-β, an antimicrobially active peptide against Gram-positive bacteria

Autor: Toshiyuki Moriizumi, Masahiro Kimura, Ikuo Kato, Aya Fujinami, Yoshiki Uchida, Noriko Tagawa, Mitsuno Shindo

Publikováno v: Chemicalpharmaceutical bulletin. 62(6)

Salusin-β has been detected in numerous mammalian tissues and has been shown to have various effects on the cardiovascular system. In this study, we showed that salusin-β exhibited potent antibacterial activity against Gram-positive microorganisms

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00545468a6c99f5c3ec23217366358c4
https://pubmed.ncbi.nlm.nih.gov/24881665

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