Zobrazeno 1 - 10
of 154
pro vyhledávání: '"Mitsunari, Nakajima"'
Publikováno v:
NeuroSci, Vol 3, Iss 3, Pp 387-394 (2022)
(1) Background: The findings of our recent in vivo study indicated that the oral administration of oenothein B, a unique macrocyclic ellagitannin, activated extracellular signal-regulated kinase (ERK) 2 and cAMP response element-binding protein (CREB
Externí odkaz:
https://doaj.org/article/7e29a41c4f4e4aee9e1db7fb2554c1d7
Publikováno v:
Antioxidants, Vol 12, Iss 3, p 779 (2023)
“Frailty” caused by a decline in physiological reserve capacity, chronic inflammation, and oxidative stress in the elderly has recently become a major social issue. The present study examined the effects of the peel of Citrus kawachiensis (CK), w
Externí odkaz:
https://doaj.org/article/7f988887c5474823bc7ff8b34e7efadc
Publikováno v:
FASEB Journal; 3/15/2024, Vol. 38 Issue 5, p1-16, 16p
Autor:
Satoshi Okuyama, Yoshiko Furukawa, Morio Yoshimura, Yoshiaki Amakura, Mitsunari Nakajima, Takashi Yoshida
Publikováno v:
Plants, Vol 10, Iss 5, p 1030 (2021)
(1) Background: Oenothein B, a cyclic dimeric ellagitannin present in various medicinal plants, has been reported to exert diverse effects that are beneficial for the treatment and prevention of diseases, including cancer and infections. We recently
Externí odkaz:
https://doaj.org/article/fe8171fc23de45c087d3b4950ff396c9
Autor:
Satoshi Okuyama, Maho Kotani, Fuga Ninomiya, Atsushi Sawamoto, Mina Fujitani, Yoshitaka Ano, Taro Kishida, Mitsunari Nakajima, Yoshiko Furukawa
Publikováno v:
Nutraceuticals; Volume 2; Issue 2; Pages: 91-101
We previously reported that the dried peel powder of Citrus kawachiensis, a citrus product of Japan, exerted anti-inflammatory and neuroprotective effects in the brains of transient global cerebral ischemia model mice. It also ameliorated the hyperph
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d18a1e82feb15c594a65f44a8916e5d9
https://doi.org/10.3390/nutraceuticals2020007
https://doi.org/10.3390/nutraceuticals2020007
Autor:
Yoshiko Furukawa, Yu-suke Washimi, Ryu-ichi Hara, Mizuki Yamaoka, Satoshi Okuyama, Atsushi Sawamoto, Mitsunari Nakajima
Publikováno v:
Molecules, Vol 25, Iss 5, p 1117 (2020)
(1) Background: Our published data have indicated that (1) auraptene (AUR), a citrus ingredient, has neuroprotective effects on the mouse brain, owing to its ability to suppress inflammation, such as causing a reduction in hyperactivation of microgli
Externí odkaz:
https://doaj.org/article/4780c2cae5c84fc0993d3c4a715ab66b
Autor:
Satoshi Okuyama, Mayu Morita, Miki Kaji, Yoshiaki Amakura, Morio Yoshimura, Koji Shimamoto, Yu Ookido, Mitsunari Nakajima, Yoshiko Furukawa
Publikováno v:
Molecules, Vol 20, Iss 11, Pp 20230-20239 (2015)
The anti-inflammatory activity of auraptene (AUR), a citrus coumarin, in peripheral tissues is well-known, and we previously demonstrated that AUR exerts anti-inflammatory effects in the ischemic brain; the treatment of mice with AUR for eight days i
Externí odkaz:
https://doaj.org/article/f71516ad137341f5b55c223df1128e7e
Autor:
Satoshi Okuyama, Mayu Morita, Atsushi Sawamoto, Tsukasa Terugo, Mitsunari Nakajima, Yoshiko Furukawa
Publikováno v:
Pharmaceuticals, Vol 8, Iss 2, Pp 176-185 (2015)
Edaravone, a clinical drug used to treat strokes, protects against neuronal cell death and memory loss in the ischemic brains of animal models through its antioxidant activity. In the present study, we subcutaneously administrated edaravone to mice (
Externí odkaz:
https://doaj.org/article/1d651c4fdf2644d08378a9b3c00706f3
Autor:
Satoshi Okuyama, Kazuhiro Miyoshi, Yuichi Tsumura, Yoshiaki Amakura, Morio Yoshimura, Takashi Yoshida, Mitsunari Nakajima, Yoshiko Furukawa
Publikováno v:
Brain Sciences, Vol 5, Iss 2, Pp 118-129 (2015)
Citrus polymethoxylated flavones (PMFs) have recently been shown to suppress inflammation in peripheral tissues. In the present study, we investigated the effects of 3,5,6,7,8,3′,4′-heptamethoxyflavone (HMF), one of the PMFs, on inflammation in t
Externí odkaz:
https://doaj.org/article/21b275d485614caeb77cbaf6f485f94e
Publikováno v:
YAKUGAKU ZASSHI. 141:819-824
Citrus kawachiensis (Kawachi Bankan), is a citrus species grown in Ehime, Japan, and its peel is abundant in 3,5,6,7,8,3',4'-heptamethoxyflavone (HMF). We have recently revealed that HMF, one of the citrus flavonoids, has anti-inflammatory activity a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::357de611f880911bf34b3b8f150d3065
https://doi.org/10.1248/yakushi.20-00251-1
https://doi.org/10.1248/yakushi.20-00251-1