Silkworm recombinant bovine zona pellucida protein 4 (bZP4) as a potential female immunocontraceptive antigen; impaired sperm-oocyte interaction and ovarian dysfunction

Autor: Ken-ichiro TATEMATSU, Mitsumi IKEDA, Yoshihiro WAKABAYASHI, Takashi YAMAMURA, Kazuhiro KIKUCHI, Junko NOGUCHI, Hideki SEZUTSU

Publikováno v: The Journal of Reproduction and Development, Vol 67, Iss 6, Pp 402-406 (2021)

Porcine zona pellucida proteins (ZPs) have been utilized as female immunocontraceptive antigens. The purpose of this study was to explore the potential use of silkworm recombinant bovine ZP4 as an alternative. When the protein was injected with monop

Externí odkaz: https://doaj.org/article/0a883557e11c4315b80bddbc87c122f3

Silkworm recombinant bovine zona pellucida protein 4 (bZP4) as a potential female immunocontraceptive antigen; impaired sperm-oocyte interaction and ovarian dysfunction

Autor: Hideki Sezutsu, Junko Noguchi, Yoshihiro Wakabayashi, Mitsumi Ikeda, Ken-Ichiro Tatematsu, Kazuhiro Kikuchi, Takashi Yamamura

Publikováno v: The Journal of Reproduction and Development

Porcine zona pellucida proteins (ZPs) have been utilized as female immunocontraceptive antigens. The purpose of this study was to explore the potential use of silkworm recombinant bovine ZP4 as an alternative. When the protein was injected with monop

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85be0a4361b61bda9c1e406e71506339
https://doi.org/10.1262/jrd.2021-103

Dynamic Changes in pStat3 Are Involved in Meiotic Spindle Assembly in Mouse Oocytes

Autor: Mitsumi Ikeda, Yuji Hirao, Satoshi Akagi, Seiki Haraguchi

Publikováno v: International Journal of Molecular Sciences, Vol 21, Iss 4, p 1220 (2020)
International Journal of Molecular Sciences
SC30202006030003
NARO成果DBa
C30202004030001_9939
Volume 21
Issue 4

The signal transducer and activator of transcription 3 (Stat3) is activated upon phosphorylation at Y705 (pStat3) and serves the dual function of signal transduction and transcription activation. Our previous study suggested that pStat3 is functional

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::231cd88889ceccd12c45a49cdf9828c7
https://www.mdpi.com/1422-0067/21/4/1220

Correction of a Disease Mutation using CRISPR/Cas9-assisted Genome Editing in Japanese Black Cattle

Autor: Koji Kimura, Katsuhiro Ohkoshi, Misa Hosoe, Mitsumi Ikeda, Shiori Minabe, Shuichi Matsuyama, Sho Nakamura, Satoshi Akagi

Publikováno v: Scientific Reports
Scientific Reports, Vol 7, Iss 1, Pp 1-9 (2017)
SC30201804130018
NARO成果DBa
C30201712210003_3158.pdf

Isoleucyl-tRNA synthetase (IARS) syndrome is a recessive disease of Japanese Black cattle caused by a single nucleotide substitution. To repair the mutated IARS gene, we designed clustered regularly interspaced short palindromic repeats (CRISPR)/CRIS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfdda7eaa2912250be79aeff4c722df8
http://europepmc.org/articles/PMC5736618

Publisher Correction: Correction of a Disease Mutation using CRISPR/Cas9-assisted Genome Editing in Japanese Black Cattle

Autor: Mitsumi Ikeda, Katsuhiro Ohkoshi, Misa Hosoe, Shuichi Matsuyama, Sho Nakamura, Satoshi Akagi, Shiori Minabe, Koji Kimura

Publikováno v: Scientific Reports, Vol 8, Iss 1, Pp 1-1 (2018)
Scientific Reports

Isoleucyl-tRNA synthetase (IARS) syndrome is a recessive disease of Japanese Black cattle caused by a single nucleotide substitution. To repair the mutated IARS gene, we designed clustered regularly interspaced short palindromic repeats (CRISPR)/CRIS

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4ef65a47ce45ecfa31ee85c202ed77eb
http://link.springer.com/article/10.1038/s41598-018-19725-z