Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Mitsumasa Sakamoto"'
Autor:
Keith W. Ward, Chun-Yue I. Lee, Sarabjit S Gahir, Mitsumasa Sakamoto, Scott A. Reisman, Joel W. Proksch
Publikováno v:
Drug Design, Development and Therapy. 13:1259-1270
Background Omaveloxolone is a synthetic oleanane triterpenoid that pharmacologically activates Nrf2, a master transcription factor that regulates genes with antioxidative, anti-inflammatory, and mitochondrial bioenergetic properties, and is being eva
Autor:
Scott A, Reisman, Sarabjit S, Gahir, Chun-Yue I, Lee, Joel W, Proksch, Mitsumasa, Sakamoto, Keith W, Ward
Publikováno v:
Drug Design, Development and Therapy
Background Omaveloxolone is a synthetic oleanane triterpenoid that pharmacologically activates Nrf2, a master transcription factor that regulates genes with antioxidative, anti-inflammatory, and mitochondrial bioenergetic properties, and is being eva
Publikováno v:
The Journal of Immunology. 200:175.22-175.22
RTA 1701 is an orally-bioavailable, selective RORγt inhibitor. RORγt orchestrates the differentiation of Th17 cells and contributes to autoimmune disease pathogenesis. Inhibition of RORγt suppresses Th17 cells and the associated secretion of the e
Autor:
Keiichi Hasegawa, Kiyoshi Ando, Mitsumasa Sakamoto, Koichi Okita, Yukio Fukushima, Shouji Kitade
Publikováno v:
TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series A. 61:1707-1712
Welded joint structural failure has been observed in the LE-7 engine main injector, which is subjected to high thermal stress during an engine start and stop sequence. Failure analysis showed that these failures were caused by extremely-low-cycle fat
Autor:
Keiichi Hasegawa, Yukio Fukushima, Shouji Kitade, Mitsumasa Sakamoto, Kiyoshi Ando, Koichi Okita
Publikováno v:
TRANSACTIONS OF THE JAPAN SOCIETY OF MECHANICAL ENGINEERS Series A. 61:1713-1718
The LE-7 rocket engine main injector has undergone a few occurrences of welded joint structural failure because it is subjected to high thermal stress during the engine start and stop sequence. The low-cycle fatigue test and high-strain fatigue test
Publikováno v:
Transactions of the Iron and Steel Institute of Japan. 25:513-520
Diffusion welding is one of the most promising fabrication methods in the aircraft industry. It realizes the complex, hollow and near-net shape structures from stock plates instead of forging materials, and the metallurgical properties of the base me