Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Mitsumasa, Kurita"'
HDAC2-dependent Antipsychotic-like Effects of Chronic Treatment with the HDAC Inhibitor SAHA in Mice
Autor:
Daisuke Ibi, Terrell Holloway, Maryum K. Ijaz, Rudy Toneatti, Jeremy Seto, Mikhail G. Dozmorov, Li Shen, Travis Cuddy, Javier González-Maeso, Mario de la Fuente Revenga, Mitsumasa Kurita, Justin M. Saunders
Publikováno v:
Neuroscience. 388:102-117
Antipsychotic drugs, including both typical such as haloperidol and atypical such as clozapine, remain the current standard for schizophrenia treatment. These agents are relatively effective in treating hallucinations and delusions. However, cognitiv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0425c36a7ea495f0ae8f88195b5978c
https://doi.org/10.1016/j.neuroscience.2018.07.010
https://doi.org/10.1016/j.neuroscience.2018.07.010
Autor:
Michael F. Miles, Travis Cuddy, Mario de la Fuente Revenga, Rudy Toneatti, Jennifer T. Wolstenholme, Daisuke Ibi, Maryum K. Ijaz, Javier González-Maeso, Mitsumasa Kurita
Publikováno v:
Neuropsychopharmacology. 44:443-454
Preclinical findings in rodent models pointed toward activation of metabotropic glutamate 2/3 (mGlu2/3) receptors as a new pharmacological approach to treat psychosis. However, more recent studies failed to show clinical efficacy of mGlu2/3 receptor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcf78b6c656e6c8678d78435cccfc0c5
https://doi.org/10.1038/s41386-018-0143-4
https://doi.org/10.1038/s41386-018-0143-4
Autor:
Yan Jiang, Carolina Muguruza, Daisuke Ibi, Carlos R. Escalante, Maryum K. Ijaz, Daniel J. Christoffel, Schahram Akbarian, Alexey Kozlenkov, Scott J. Russo, Nebojsa Kezunovic, Vishaka Santosh, Jeremy Seto, Javier González-Maeso, Terrell Holloway, Supriya A Gaitonde, Luis F. Callado, J. Javier Meana, Mario de la Fuente Revenga, José L. Moreno, Stella Dracheva, Mitsumasa Kurita, Grace E. Mosley, George W. Huntley, Juan F. López-Giménez, Aintzane García-Bea, Yongchao Ge, Justin M. Saunders
Publikováno v:
Digital.CSIC. Repositorio Institucional del CSIC
instname
instname
Ibi, Daisuke et al.
Antipsychotic drugs remain the standard for schizophrenia treatment. Despite their effectiveness in treating hallucinations and delusions, prolonged exposure to antipsychotic medications leads to cognitive deficits in both sc
Antipsychotic drugs remain the standard for schizophrenia treatment. Despite their effectiveness in treating hallucinations and delusions, prolonged exposure to antipsychotic medications leads to cognitive deficits in both sc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::66464623ccb19b82f6f131f694dde974
https://pubmed.ncbi.nlm.nih.gov/28783139
https://pubmed.ncbi.nlm.nih.gov/28783139
Autor:
Mario de la Fuente Revenga, Daisuke Ibi, Travis Cuddy, Rudy Toneatti, Mitsumasa Kurita, Maryum K. Ijaz, Michael F. Miles, Jennifer T. Wolstenholme, Javier González-Maeso
Publikováno v:
Neuropsychopharmacology. 44:455-456
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22c45b3b748349540b4b1116513a8a82
https://doi.org/10.1038/s41386-018-0255-x
https://doi.org/10.1038/s41386-018-0255-x
Autor:
Aintzane García-Bea, Eric J. Nestler, James B. Hanks, José L. Moreno, Terrell Holloway, Rachael L. Neve, Mitsumasa Kurita, Giuseppe Mocci, Scott J. Russo, Alexey Kozlenkov, Javier González-Maeso
Publikováno v:
Molecular Pharmacology. 83:1166-1175
Serotonin 5-HT(2A) and metabotropic glutamate 2 (mGlu2) are G protein-coupled receptors suspected in the pathophysiology of psychiatric disorders, such as schizophrenia, depression, and suicide. Previous findings demonstrate that mGlu2 mRNA expressio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::be61e79e0bcab3cd0f3f669dfaea37b0
https://doi.org/10.1124/mol.112.084582
https://doi.org/10.1124/mol.112.084582
Publikováno v:
The Medical Basis of Psychiatry ISBN: 9781493925278
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9da824dcfd9f973a7b8ec390f17d0731
https://doi.org/10.1007/978-1-4939-2528-5_30
https://doi.org/10.1007/978-1-4939-2528-5_30
Autor:
Javier González-Maeso, Mitsumasa Kurita, Richard Cadagan, José L. Moreno, Adolfo García-Sastre, Luis Martinez-Sobrido, Terrell Holloway, Javier López
Publikováno v:
The Journal of Neuroscience. 31:1863-1872
Epidemiological studies indicate that maternal influenza viral infection increases the risk for schizophrenia in the adult offspring. The serotonin and glutamate systems are suspected in the etiology of schizophrenia, as well as in the mechanism of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::88e028f4f049b9b83aa485753c87fcdf
https://doi.org/10.1523/jneurosci.4230-10.2011
https://doi.org/10.1523/jneurosci.4230-10.2011
Publikováno v:
Nucleic Acids Research
Transcriptional repression of the silent mating-type loci HMLalpha and HMRa in Saccharomyces cerevisiae is regulated by chromatin structure. Sas2p is a catalytic subunit of the SAS histone acetyltransferase (HAT) complex. Although many HATs seem to r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01bd9a857878cf3c70dce668ff032987
https://doi.org/10.1093/nar/gki560
https://doi.org/10.1093/nar/gki560
Publikováno v:
Expert review of neurotherapeutics. 13(1)
One of the main characteristics of treatment of psychiatric disorders, such as schizophrenia and depression, is the chronic administration (weeks, months or even years) of therapeutic compounds. A ...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5cf093557fba819a77554efb93bbe63c
https://pubmed.ncbi.nlm.nih.gov/23253383
https://pubmed.ncbi.nlm.nih.gov/23253383
Autor:
José L, Moreno, Mitsumasa, Kurita, Terrell, Holloway, Javier, López, Richard, Cadagan, Luis, Martínez-Sobrido, Adolfo, García-Sastre, Javier, González-Maeso
Publikováno v:
The Journal of neuroscience : the official journal of the Society for Neuroscience. 31(5)
Epidemiological studies indicate that maternal influenza viral infection increases the risk for schizophrenia in the adult offspring. The serotonin and glutamate systems are suspected in the etiology of schizophrenia, as well as in the mechanism of a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::00f012617b3f46d2e8ee198b2b14ff80
https://pubmed.ncbi.nlm.nih.gov/21289196
https://pubmed.ncbi.nlm.nih.gov/21289196