Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Mitsukuni Yoshida"'
Autor:
Jonathan B. Lin, Shunsuke Kubota, Norimitsu Ban, Mitsukuni Yoshida, Andrea Santeford, Abdoulaye Sene, Rei Nakamura, Nicole Zapata, Miyuki Kubota, Kazuo Tsubota, Jun Yoshino, Shin-ichiro Imai, Rajendra S. Apte
Publikováno v:
Cell Reports, Vol 17, Iss 1, Pp 69-85 (2016)
Photoreceptor death is the endpoint of many blinding diseases. Identifying unifying pathogenic mechanisms in these diseases may offer global approaches for facilitating photoreceptor survival. We found that rod or cone photoreceptor-specific deletion
Externí odkaz:
https://doaj.org/article/ad5b3619cf5149aa8ea7fff5633aedfd
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Phenotypic and genetic intra-tumor heterogeneity have an important role in cancer progression and therapeutic resistance. Here, the authors show that phenotypically variable tumor subpopulations exhibit higher metastatic potential and display enhance
Externí odkaz:
https://doaj.org/article/7e299b798cc044399ba376b2b8746bde
Autor:
Mitsukuni Yoshida
Publikováno v:
Review of Japanese Culture and Society. 32:63-70
Autor:
Andrea Santeford, Shin-ichiro Imai, Kazuo Tsubota, Mitsukuni Yoshida, Jun Yoshino, Shunsuke Kubota, Miyuki Kubota, Nicole Zapata, Abdoulaye Sene, Norimitsu Ban, Rei Nakamura, Rajendra S. Apte, Jonathan B. Lin
Publikováno v:
Cell Reports, Vol 17, Iss 1, Pp 69-85 (2016)
Summary Photoreceptor death is the endpoint of many blinding diseases. Identifying unifying pathogenic mechanisms in these diseases may offer global approaches for facilitating photoreceptor survival. We found that rod or cone photoreceptor-specific
Autor:
Maria Angulo-Ibanez, Johan Auwerx, Katrin F. Chua, William Giblin, David Gius, Leonard Guarente, Angela H. Guo, Marcia C. Haigis, Sylvana Hassanieh, Kathleen A. Hershberger, Matthew D. Hirschey, Shin-ichiro Imai, Alice E. Kane, Elena Katsyuba, Aleksey G. Kazantsev, Hening Lin, David B. Lombard, Sébastien Moniot, Raul Mostoslavsky, Tiago F. Outeiro, David A. Sinclair, Clemens Steegborn, Adam B. Stein, Éva M. Szegő, Robert A.H. van de Ven, Athanassios Vassilopoulos, Rui-Hong Wang, Wen Yang, Mitsukuni Yoshida, Weijie You
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::43cec83b0e139b92c8d36f2a223b81f4
https://doi.org/10.1016/b978-0-12-813499-3.00018-6
https://doi.org/10.1016/b978-0-12-813499-3.00018-6
Autor:
Shin-ichiro Imai, Mitsukuni Yoshida
In recent years, nicotinamide adenine dinucleotide (NAD + ) biology has been increasingly drawing significant attention within the scientific community and providing its vast implication for various age-associated pathophysiologies and disease condit
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::5a5c5f53bba8299239858bbdc6680157
https://doi.org/10.1016/b978-0-12-813499-3.00002-2
https://doi.org/10.1016/b978-0-12-813499-3.00002-2
SIRT1-Mediated eNAMPT Secretion from Adipose Tissue Regulates Hypothalamic NAD+ and Function in Mice
Autor:
Shin-ichiro Imai, Akiko Takikawa, Isao Usui, Kazuyuki Tobe, Myeong Jin Yoon, Mitsukuni Yoshida, Jun Yoshino, Sean Johnson, Takashi Nakagawa
Publikováno v:
Cell Metabolism. 21(5):706-717
Summary Nicotinamide phosphoribosyltransferase (NAMPT), the key NAD + biosynthetic enzyme, has two different forms, intra- and extracellular (iNAMPT and eNAMPT), in mammals. However, the significance of eNAMPT secretion remains unclear. Here we demon
Autor:
Yo Sasaki, Nicholas Rensing, Jonathan B. Lin, Michael Wong, Rajendra S. Apte, Akiko Satoh, Kathryn F. Mills, Shin-ichiro Imai, Mitsukuni Yoshida
Publikováno v:
Cell Metab
Aging is a significant risk factor for impaired tissue functions and chronic diseases. Age-associated decline in systemic NAD(+) availability plays a critical role in regulating the aging process across many species. Here we show that the circulating
Publikováno v:
Goodarzi, Hani; Nguyen, A; Yoshida, M; & Tavazoie, SF. (2016). Highly variable cancer subpopulations that exhibit enhanced transcriptome variability and metastatic fitness.. UC San Francisco: Retrieved from: http://www.escholarship.org/uc/item/5cs065c2
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Nature Communications
Nature Communications, Vol 7, Iss 1, Pp 1-13 (2016)
Nature Communications
Individual cells within a tumour can exhibit distinct genetic and molecular features. The impact of such diversification on metastatic potential is unknown. Here we identify clonal human breast cancer subpopulations that display different levels of m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29f9f4596331e947a1ad7818f71c12c0
http://www.escholarship.org/uc/item/5cs065c2
http://www.escholarship.org/uc/item/5cs065c2
Publikováno v:
Genes & development, vol 30, iss 4
Post-transcriptional deregulation is a defining feature of metastatic cancer. While many microRNAs have been implicated as regulators of metastatic progression, less is known about the roles and mechanisms of RNA-binding proteins in this process. We
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8cb8a6318442d4b6b37710ebe9cd1825
https://europepmc.org/articles/PMC4762424/
https://europepmc.org/articles/PMC4762424/