Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Mitsuko Ohno"'
Autor:
Yoshimi Hirasawa, Mitsuko Ohno, Shigetaka Nishino, Yasuhiro Kita, Masayuki Kato, Yasuko Kato, Shinichi Fukuyama
Publikováno v:
Drug Development Research. 61:37-43
FR 146801 (±)-N-[(E)-4-ethyl-3-[(Z)-hydroxyimino]-6-methyl-5-nitro-3-heptenyl]-3-pyridinecarboxamide is a novel nitric oxide (NO) donating agent. In the present study, we examined the effect of FR146801, a slow NO releaser, on intimal thickening of
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7de2dce57d3700fdaa9d3e84a24ec712
https://doi.org/10.1002/ddr.10335
https://doi.org/10.1002/ddr.10335
Autor:
Yousuke Katsura, Mitsuko Ohno, Hirohumi Ishikawa, Kazuo Sakane, Shigetaka Nishino, Chizu Morinaga, Hisashi Takasugi, Yoshimi Matsumoto
Publikováno v:
Journal of Medicinal Chemistry. 42:2920-2926
A series of 2-[(arylalkyl)guanidino]-4-[(5-acetamidomethyl)furan-2-yl]thiazole s and some 4-acetamidomethyl positional isomers were synthesized and evaluated for antimicrobial activity against Helicobacter pylori. Among the compounds that had potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::df3a6961206a99be453a2a762c6eaf64
https://doi.org/10.1021/jm9900671
https://doi.org/10.1021/jm9900671
Autor:
Yasuko Kato, Shigetaka Nishino, Mitsuko Ohno, Jiro Seki, Yasuhiro Kita, Kazuhiro Maeda, Shinichi Fukuyama, Masayuki Kato, Hiroyuki Takamatu, Toshiko Sugimoto, Yoshimi Hirasawa
Publikováno v:
European Journal of Pharmacology. 303:55-59
The aim of this study was to compare the antianginal effects of two compounds that release nitric oxide (NO) spontaneously, i.e. (+/-)-N-[(E)-4-ethyl-3-[(Z-hydroxyimino]-5-nitro-3-hexenyl] -3-pyridinecarboxamide (FR144420) and (+/-)-(E)-ethyl-2-[(E)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b6f612a40cf26d6eea6bcea580cca65
https://doi.org/10.1016/0014-2999(96)00105-7
https://doi.org/10.1016/0014-2999(96)00105-7
Autor:
Masayuki Kato, Isao Nakanishi, Yasuhiro Kita, Shigetaka Nishino, Mitsuko Ohno, Shinichi Fukuyama, Kazuo Sakane, Hisashi Takasugi, Yoshimi Hirasawa
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 6:33-38
The synthesis and structure-stability relationships of a series of novel FK409 derivatives ( 1 , 2 , and 3 ) are described. The rates of decomposition in aqueous solution (pH 8.0, 30 °C) were parallel with those of spontaneous NO release measured by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::af5eec3966a9e22e051bc6526f5d43d5
https://doi.org/10.1016/0960-894x(95)00547-7
https://doi.org/10.1016/0960-894x(95)00547-7
Autor:
Shigetaka Nishino, Yasuhiro Kita, Kazumi Ohkubo, Masayuki Kato, Keizo Yoshida, Mitsuko Ohno, Yoshimi Hirasawa, Yoshiki Katayama
Publikováno v:
European Journal of Pharmacology. 275:125-130
We report that (+/-)-(E)-ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexeneamide (FK409) decomposes and releases nitric oxide (NO) spontaneously in solution. (+/-)-N-[(E)-4-Ethyl-3-[(Z)-hydroxyimino]-5-nitro-3-hexen-1- yl]-3- pyridinecarboxamide (FR144420)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a780aa33babeec8d9566ad67ea6eb7d
https://doi.org/10.1016/0014-2999(94)00750-2
https://doi.org/10.1016/0014-2999(94)00750-2
Autor:
Shinichi Fukuyama, Isao Nakanishi, Yasuhiro Kita, Hisashi Takasugi, Shigetaka Nishino, Kazuo Sakane, Masayuki Kato, Mitsuko Ohno, Yoshimi Hirasawa
Publikováno v:
ChemInform. 27
The synthesis and structure-stability relationships of a series of novel FK409 derivatives ( 1 , 2 , and 3 ) are described. The rates of decomposition in aqueous solution (pH 8.0, 30 °C) were parallel with those of spontaneous NO release measured by
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1e346b244a3999a3b8537ff0a229420e
https://doi.org/10.1002/chin.199617062
https://doi.org/10.1002/chin.199617062
Autor:
Yasuhiro Kita, Masayuki Kato, Shigetaka Nishino, Shinichi Fukuyama, Mitsuko Ohno, Yoshimi Hirasawa, Yasuko Kato
Publikováno v:
Thrombosis and haemostasis. 79(3)
SummaryIn the present study, we examined the antiplatelet effects of the two nitric oxide (NO)-donating agents, (±)-N -[(E)-4-ethyl-3-[(Z)hydroxyimino]-6-methyl-5-nitro-3-heptenyl]-3-pyridinecarboxamide (FR146801), a more stable analog of FK409 ((±
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f3075e4b9dc445b406f066a9d586a1a
https://pubmed.ncbi.nlm.nih.gov/9531052
https://pubmed.ncbi.nlm.nih.gov/9531052
Autor:
Shinichi Fukuyama, Masayuki Kato, Yasuko Kato, Kazumi Ohkubo, Yoshimi Hirasawa, Yasuhiro Kita, Sigetaka Nishino, Mitsuko Ohno
Publikováno v:
Journal of cardiovascular pharmacology. 30(2)
The aim of this study was to compare the hemodynamic effects of three nitric oxide (NO) donors [i.e., (+/-)-(E)-ethyl-2-[(E)-hydroxyimino]-5-nitro-3-hexenamide (FK409), (+/-)-N-[(E)-4-ethyl-3-[(Z)-hydroxyimino]-6-methyl-5-nitro-3-he ptenyl]-3-pyridin
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::240af2c87eaf4d2b120b8a048886ee26
https://pubmed.ncbi.nlm.nih.gov/9269950
https://pubmed.ncbi.nlm.nih.gov/9269950
Autor:
Yoshimi Hirasawa, Yasuko Kato, Shinichi Fukuyama, Mitsuko Ohno, Shigetaka Nishino, Masayuki Kato, Yasuhiro Kita
Publikováno v:
Drug Development Research; Jan2004, Vol. 61 Issue 1, p37-43, 7p