Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Mitsuko Kosaka"'
Autor:
Seijiro Koshimune, Mitsuko Kosaka, Nobuhiko Mizuno, Hiromasa Yamamoto, Tomoyuki Miyamoto, Kohta Ebisui, Shinichi Toyooka, Aiji Ohtsuka
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)
Abstract Background Octamer-binding transcription factor 4A (OCT4A) is essential for cell pluripotency and reprogramming both in humans and mice. To date, however, the function of human OCT4 in somatic and/or tumour tissues is largely unknown. Method
Externí odkaz:
https://doaj.org/article/c49046ca89614d1e9b8906dc6f82f864
Autor:
Mitsuko Kosaka, Shinichi Toyooka, Nobuhiko Mizuno, Aiji Ohtsuka, Seijiro Koshimune, Kohta Ebisui, Tomoyuki Miyamoto, Hiromasa Yamamoto
Publikováno v:
BMC Cancer, Vol 20, Iss 1, Pp 1-13 (2020)
BMC Cancer
BMC Cancer
Background Octamer-binding transcription factor 4A (OCT4A) is essential for cell pluripotency and reprogramming both in humans and mice. To date, however, the function of human OCT4 in somatic and/or tumour tissues is largely unknown. Methods RT-PCR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a2bfd42c4d5c32a1349b2687d2383978
http://link.springer.com/article/10.1186/s12885-020-06969-0
http://link.springer.com/article/10.1186/s12885-020-06969-0
Autor:
Kyohei Irie, Nobuhiko Mizuno, Tomoyuki Miyamoto, Aiji Ohtsuka, Hiromasa Yamamoto, Shinichi Toyooka, Hisashi Masuyama, Mitsuko Kosaka
Publikováno v:
Cancer Research. 82:5125-5125
Background: It is largely unclear whether octamer-binding transcription factor 4A (OCT4A, OCT3/4A) functions physiologically or pathologically in adult somatic tissues and related cancers. We have recently identified OCT4A translation in a human canc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9ef8c4740d0ede9b2a2e79fdc9ff8103
https://doi.org/10.1158/1538-7445.am2022-5125
https://doi.org/10.1158/1538-7445.am2022-5125
Publikováno v:
Stem Cells. 36:1341-1354
The role of octamer-binding transcription factor 4 (OCT4) in human cancer is still debated. Although many studies have been published on human OCT4, determining which of the findings are accurate or which are false-positives is currently challenging.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0abb6375a7a1dc2166da505a5f39caa1
https://doi.org/10.1002/stem.2851
https://doi.org/10.1002/stem.2851
Autor:
Nobuhiko Mizuno, Mitsuko Kosaka
Publikováno v:
Journal of Biological Chemistry. 283:30997-31004
It has been suggested that Oct-3/4 may regulate self-renewal in somatic stem cells, as it does in embryonic stem cells. However, recent reports raise the possibility that detection of human Oct-3/4 expression by RT-PCR is prone to artifacts generated
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44031c984bfa441abef58406329f725c
https://doi.org/10.1074/jbc.m802992200
https://doi.org/10.1074/jbc.m802992200
Publikováno v:
Developmental Biology. 304(1):433-446
The regeneration of lens tissue from the iris of newts has become a classical model of developmental plasticity, although little is known about the corresponding plasticity of the mammalian iris. We here demonstrate and characterize multipotent cells
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::afe4258b507b21bb23c37bce077af2b7
Publikováno v:
Biochemical and Biophysical Research Communications. 316:1-5
We investigated the ability of adult human RPE cells to differentiate into neurons. Two cell lines were evaluated. The cells were cultured in medium with 8% serum, transferred to a neural stem cell maintenance culture, and induced to differentiate wi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::16c9eae42db4578bdc8dfb74bb140110
https://doi.org/10.1016/j.bbrc.2004.01.172
https://doi.org/10.1016/j.bbrc.2004.01.172
Publikováno v:
Experimental Cell Research. 245:245-251
Dissociated cells of the iris-pigmented epithelium (IPE) from a 1-day-old chick grew in monolayer culture and stably maintained their differentiated state when cultured with standard culture medium. After replacement of the control medium by EdFPH me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d8d915f7447c180fd2dcc3cc0d950b25
https://doi.org/10.1006/excr.1998.4211
https://doi.org/10.1006/excr.1998.4211
Autor:
Lars Royall, Mitsuko Kosaka, Satoshi Kagiwada, Tamami Matsushita, Ai Fujihara, Masasuke Araki
Publikováno v:
Experimental eye research. 123
A simple culture method that was recently developed in our laboratory was applied to the chick iris tissues to characterize neural stem/progenitor-like cells. Iris tissue is a non-neuronal tissue and does not contain any neuronal cells. In the presen
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0b1c0c5d5af2dab4e1f0a2d0eece1b7b
https://pubmed.ncbi.nlm.nih.gov/24747800
https://pubmed.ncbi.nlm.nih.gov/24747800
Autor:
Ichiro Naito, Ryuichi Nakahara, Eri Shiratsuchi, Mitsuko Kosaka, Kanae Kumagishi, Ryusuke Momota, Akira Shinaoka, Aiji Ohtsuka
Publikováno v:
Microscopy and microanalysis : the official journal of Microscopy Society of America, Microbeam Analysis Society, Microscopical Society of Canada. 19(2)
Most blood vessels contain elastin that provides the vessels with the resilience and flexibility necessary to control hemodynamics. Pathophysiological hemodynamic changes affect the remodeling of elastic components, but little is known about their st
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7cf18a175c59afbf8ee5a883bd8cc472
https://pubmed.ncbi.nlm.nih.gov/23453051
https://pubmed.ncbi.nlm.nih.gov/23453051