Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Mitsuko Ishihara-Sugano"'
Autor:
Asako Murayama, Nao Sugiyama, Seiko Yoshimura, Mitsuko Ishihara-Sugano, Takahiro Masaki, Sulyi Kim, Takaji Wakita, Shunji Mishiro, Takanobu Kato
Publikováno v:
PLoS ONE, Vol 7, Iss 12, p e52697 (2012)
Hepatitis C virus (HCV) cell culture system with JFH-1 strain and HuH-7 cells enabled us to produce infectious HCV particles in vitro, and such system is useful to explore the anti-HCV compounds and to develop the vaccine against HCV. In the present
Externí odkaz:
https://doaj.org/article/968475d952d14e68a9db156dba57fca4
Autor:
Shoji Saito, Mitsuko Ishihara-Sugano, Eiichi Akahoshi, Yozo Nakazawa, Ikumi Nakashima, Aiko Hasegawa, Shigeki Yagyu
Publikováno v:
Blood. 136:21-22
Introduction : Treatment options for relapsed T cell leukemia are limited, and the prognosis remains dismal. Therefore, the development of new therapies is crucial. A liposomal delivery system has been increasingly recognized as a promising strategy
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cf466f6388b7ec897131efd9683d24f9
https://doi.org/10.1182/blood-2020-139020
https://doi.org/10.1182/blood-2020-139020
Autor:
Youhei Mantani, Yuria Umemura, Tetsushi Hirano, Mitsuko Ishihara-Sugano, Toshifumi Yokoyama, Shogo Yanai, Natsumi Masuda, Hideto Yuasa, Takuya Omotehara, Kiichi Minami, Yoshihiro Kobayashi, Naoto Kubota, Nobuhiko Hoshi, Rie Hashimoto, Hiroshi Kitagawa
Publikováno v:
The Journal of Veterinary Medical Science
Dioxins are widespread persistent environmental contaminants with adverse impacts on humans and experimental animals. Behavioral and cognitive functions are impaired by 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) exposure. TCDD exerts its toxicity via
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee98ff4291675da464d2d47fcfe391d6
https://doi.org/10.1292/jvms.15-0238
https://doi.org/10.1292/jvms.15-0238
Autor:
Junko Tokumoto, Michiko Saito, Daichi Nagahara, Mitsuko Ishihara-Sugano, Nobuhiko Hoshi, Megumi Danjo, Eiichi Akahoshi, Takashi Tanida, Hiroshi Kitagawa, Shigehisa Kawata, Ken Tasaka, Youhei Mantani, Mitsuhiro Kawata, Toshifumi Yokoyama, Yoshiaki Tabuchi
Publikováno v:
Journal of Applied Toxicology. 34:117-126
Fetal exposure to dioxins and related compounds is known to disrupt normal development of the midbrain dopaminergic system, which regulates behavior, cognition and emotion. The toxicity of these chemicals is mediated mainly by aryl hydrocarbon recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b0da3c616541963a4800bcd2c49977df
https://doi.org/10.1002/jat.2839
https://doi.org/10.1002/jat.2839
Autor:
Satoshi Sawamura, Eri Yoshikawa, Satoshi Itoh, Mitsuko Ishihara-Sugano, Satoshi Miyagi, Kenichi Dedachi, Noriyuki Kurita
Publikováno v:
International Journal of Quantum Chemistry. 112:289-299
Aryl hydrocarbon receptor (AhR) regulates expression of genes in a ligand-dependent manner. Although AhR was found to contain basic helix-loop-helix and Per-Arnt-Sim (PAS) domains, three-dimensional structures of AhR and its complex with ligand have
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f747f4fc3e4a2ea52ce85bcf3df5ffa0
https://doi.org/10.1002/qua.23212
https://doi.org/10.1002/qua.23212
Autor:
Satoshi Itoh, Eri Yoshikawa, Kenichi Dedachi, Satoshi Miyagi, Noriyuki Kurita, Mitsuko Ishihara-Sugano
Publikováno v:
Journal of Computer Aided Chemistry. 10:63-75
芳香族炭化水素受容体(AhR: Arylhydrocarbon receptor)は、内分泌撹乱物質等の外来異物が生体内に取り込まれた時に、これらを結合し、その情報を核に伝え、代謝酵素の発現を誘導することが明
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::499a1f1dce5f7752fb559b729bdb797e
https://doi.org/10.2751/jcac.10.63
https://doi.org/10.2751/jcac.10.63
Autor:
Seiko Yoshimura, Noriyuki Kurita, Saeko Uruno, Kazuya Sashino, Satoshi Miyagi, Kyoshiro Murata, Mitsuko Ishihara-Sugano, Eiichi Akahoshi, Satoshi Itoh, Satoshi Sawamura
Aryl hydrocarbon receptor (AhR) plays critical roles in cell differentiation, and its mechanism is controlled by exogenous and endogenous ligands. However, structures of AhR and its complex with ligand have not been determined by experimental structu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e628ba0cee648f5153117d3353c54715
Autor:
Takanobu Kato, Shunji Mishiro, Takaji Wakita, Takahiro Masaki, Nao Sugiyama, Seiko Yoshimura, Sulyi Kim, Mitsuko Ishihara-Sugano, Asako Murayama
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 12, p e52697 (2012)
PLoS ONE, Vol 7, Iss 12, p e52697 (2012)
Hepatitis C virus (HCV) cell culture system with JFH-1 strain and HuH-7 cells enabled us to produce infectious HCV particles in vitro, and such system is useful to explore the anti-HCV compounds and to develop the vaccine against HCV. In the present
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab48174ff4b8a534a11fa30c829e00aa
http://europepmc.org/articles/PMC3527576
http://europepmc.org/articles/PMC3527576
Autor:
Takashi, Tanida, Ken, Tasaka, Eiichi, Akahoshi, Mitsuko, Ishihara-Sugano, Michiko, Saito, Shigehisa, Kawata, Megumi, Danjo, Junko, Tokumoto, Youhei, Mantani, Daichi, Nagahara, Yoshiaki, Tabuchi, Toshifumi, Yokoyama, Hiroshi, Kitagawa, Mitsuhiro, Kawata, Nobuhiko, Hoshi
Publikováno v:
Journal of applied toxicology : JAT. 34(2)
Fetal exposure to dioxins and related compounds is known to disrupt normal development of the midbrain dopaminergic system, which regulates behavior, cognition and emotion. The toxicity of these chemicals is mediated mainly by aryl hydrocarbon recept
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::16157a093c87414cf7c83af968262dfc
https://pubmed.ncbi.nlm.nih.gov/23296914
https://pubmed.ncbi.nlm.nih.gov/23296914
Publikováno v:
Toxicology mechanisms and methods. 22(6)
Tyrosine hydroxylase (TH) assay is a novel bioassay for screening aryl hydrocarbon receptor (AhR)-active compounds with diverse toxicities. The TH assay employs reporter genes to evaluate TH promoter activity, which is linked to dopamine synthesis an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::269bdfc32fce599aab6ea383fe681b29
https://pubmed.ncbi.nlm.nih.gov/22394336
https://pubmed.ncbi.nlm.nih.gov/22394336