Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Mitsuko Isaji"'
Autor:
Arvind K. Singh Chandel, Seiichi Ohta, Machiko Taniguchi, Hiromi Yoshida, Daichi Tanaka, Kiyohiko Omichi, Atsushi Shimizu, Mitsuko Isaji, Kiyoshi Hasegawa, Taichi Ito
Publikováno v:
Biomaterials advances. 137
In surgery, both antiperitoneal adhesion barriers and hemostats with high efficiency and excellent handling are necessary. However, antiadhesion and hemostasis have been examined separately. In this study, six different ultrapure alginate bilayer spo
Autor:
Hiroyuki Wakabayashi, Masaaki Naotsuka, Tomohiro Mega, Toshinori Kanamori, Shunji Natsuka, Kiyoshi Sakai, Naoki Otsuki, Sadatoshi Koyama, Mitsuko Isaji, Sumihiro Hase
Publikováno v:
Journal of Biological Chemistry. 274:5436-5442
O-linked sugar chains with xylose as a reducing end linked to human urinary soluble thrombomodulin were studied. Sugar chains were liberated by hydrazinolysis followed by N-acetylation and tagged with 2-aminopyridine. Two fractions containing pyridyl
Autor:
Akio Uemura, Jiro Hirose, Toshiko Ozawa, Yuji Nagao, Toshihisa Miura, Mitsuko Isaji, Atsushi Nii, Katsuaki Kato, Kazuya Yamashiro
Publikováno v:
Biological and Pharmaceutical Bulletin. 21:651-656
Urinary trypsin inhibitor (UTI) is a physiological protease inhibitor and inter-alpha-trypsin inhibitor (ITI) is regarded as a precursor of UTI. The purpose of this study is to determine the mechanism of the UTI release from ITI. To examine this, ITI
Autor:
Keisuke Sugihara, Hideaki Morishita, Toshinori Kanamori, Hideaki Umeyama, Jiro Hirose, Mitsuko Isaji, Tomokazu Matsusue, Toshihisa Miura, Yoshifumi Horisawa, Toru Yamakawa, Atsushi Nii
Publikováno v:
The Journal of Biochemistry. 115:1107-1112
The second domain (R-020) of human urinary trypsin inhibitor (UTI) exerts similar inhibitory activities on trypsin, alpha-chymotrypsin, leukocyte elastase, and plasmin to those of UTI itself, and additionally inhibits coagulation factor Xa (FXa) and
Autor:
Tetsuya Masuda, Hideki Sasaki, Tohru Inoue, Kazuharu Kato, Kiyoshi Takatsuki, Jiro Hirose, Mitsuko Isaji, Hiromitsu Matsuzaki, Yuji Yonemura, Makoto Kawakita, Koji Fujimoto
Publikováno v:
Biochemical and Biophysical Research Communications. 174:1163-1168
We purified a protein possessing a potent ability to induce the differentiation of a murine megakaryoblastic cell line, L8057, from the supernatant of a human fibrous histiocytoma cell line, KHM-5M. The protein, a homodimer of a molecular weight of 2
Autor:
Kouichi Noda, Takeshi Kusuyama, Yoshifumi Horisawa, Hiromi Ogino, Tetsuya Asami, Hidemi Ohta, Mitsuko Isaji, Ryo Tanaka
Publikováno v:
Japanese Journal of Thrombosis and Hemostasis. 2:461-468
Purified natural human fibroblast-derived interleukin-6 (nhlL-6) was obtained from a culture of a normal human fibroblast cell strain, and its effect on the platelet number in normal mice was examined.The platelet number in female BDF1 mice given sub
Autor:
Mitsuko Isaji, Naohiko Koshikawa, Takashi Nakamura, Naoto Tsuchiya, Hidetaro Yasumitsu, Kaoru Miyazaki, Makoto Umeda
Publikováno v:
Journal of biochemistry. 119(2)
Our previous studies have shown that some human cancer cell lines produce pancreatic trypsinogen, plasminogen, and tissue-type kallikrein. To understand the regulatory mechanism of these proteinases, serine proteinase inhibitors secreted by human gli
Autor:
Rie Sameshima-Aruga, Yasukazu Nagase, Tomokazu Matsusue, Masahiro Nobuhara, Toru Yamakawa, Atsushi Nii, Sadatoshi Koyama, Jiro Hirose, Reiko Horisawa-Nakano, Masaaki Naotsuka, Mitsuko Isaji, Toshihisa Miura, Hideaki Morishita, Ryo Tanaka, Takeshi Kusuyama, Toshinori Kanamori
Publikováno v:
Thrombosis research. 73(3-4)
Urinary trypsin inhibitor is a glycoprotein with a structure in which two Kunitz-type inhibitory domains are linked in a row. We isolated two genes encoding the 70 amino acid sequence from the 78th amino acid (Thr) to the C-terminal and the 68 amino